Article
Chemistry, Multidisciplinary
George M. Neville, Karen J. Edler, Gareth J. Price
Summary: Fluorescently-labelled variants of poly(styrene-co-maleic acid) have been synthesized by RAFT copolymerization and shown to form nanodiscs when interacting with lipids. These novel copolymers can encapsulate lipids and membrane proteins, making them potentially useful in fluorescence-based biological studies.
Article
Biochemistry & Molecular Biology
Bikash R. Sahoo, Christopher L. Souders, Takahiro Watanabe-Nakayama, Zhou Deng, Hunter Linton, Saba Suladze, Magdalena I. Ivanova, Bernd Reif, Toshio Ando, Christopher J. Martyniuk, Ayyalusamy Ramamoorthy
Summary: This study demonstrates that synthetic copolymer derivatives can alter amylin aggregation and modulate its conformation, providing insights into the mechanism of amylin pathogenic formation.
JOURNAL OF MOLECULAR BIOLOGY
(2022)
Article
Polymer Science
Chuxuan Chen, Can Xu, Jiaxin Zhai, Yuhong Ma, Changwen Zhao, Wantai Yang
Summary: A solvent-free method was developed to prepare uniform SMI microspheres from SMA and gaseous amine, leading to improved thermal properties, enhanced solubility, and superior surface characteristics compared to SMA microspheres.
Article
Engineering, Chemical
Guijing Chen, Yuanyuan Yang, Dongdong Kang, Qingqing Qin, Jinbo Jin, Huiju Shao, Shuhao Qin
Summary: Blending styrene-maleic anhydride copolymer (SMA) with CPVC can improve the performance of ultrafiltration membranes by adjusting microstructures, increasing pure water flux and permeability, reducing irreversible fouling index, and enhancing flux recovery ratio.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Spectroscopy
Suosuo An, Shuang Meng, Jiadan Xue, Huigang Wang, Xuming Zheng, Yanying Zhao
Summary: This paper investigates the photophysical and photochemical reactions of 1,2,4-triazole-3-thione in solid, protic, and aprotic solvents, confirming the structures of microsolvation clusters and identifying the intermolecular hydrogen bonding effects through a combination of experimental and computational methods. The results show significant spectrum shifts in Raman and absorption spectra of 3TT in different solvents, indicating the importance of hydrogen bonding interactions in the photophysical and photochemical processes.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Review
Polymer Science
Sagar Bag, Soumyadeep Ghosh, Soumya Paul, Md Ezaz Hasan Khan, Priyadarsi De
Summary: S-MI/MA alternating copolymers, known for their tunable molecular weight, narrow dispersity, and precise chain-end functionality, have recently been discovered to exhibit unprecedented emissive behavior, outperforming traditional fluorophores. They are easy to synthesize, utilize cheap starting materials, can be functionalized post-polymerization, exhibit aqueous solubility, and offer greater cell viability.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Article
Chemistry, Physical
Gurleen Singh, Riddima Singh, Nancy George, Gurjaspreet Singh, Pinky Satija, Gurpreet Kaur, Harminder Singh, Jandeep Singh
Summary: This report describes the synthesis of two novel 1,2,3-triazole-based chemosensors appended with maleic hydrazide for selective recognition of Pb(II) and Cr(III) using Copper(I) catalyzed alkyne-azide cycloaddition (CuAAC) reaction. The probes were characterized and their ion sensing behavior in DMSO solvent was studied using UV-Vis spectroscopy. The association constants for the probes with Pb(II) and Cr(III) were determined, and their potential anti-inflammatory properties were investigated through docking analysis.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Polymer Science
Qing Zhang, Yongguang Gao, Baojing Luo, Yan Cui, Shili Shu, Wei Chen, Lei Wang
Summary: Poly(butylene succinate-butylene terephthalate) (PBST) and polylactic acid (PLA) were blended using styrene-maleic anhydride copolymer (PSMA) as a compatibilizer. The addition of PSMA improved the compatibility between PBST and PLA, resulting in enhanced mechanical properties. The blends exhibited shear-thinning behavior and belonged to pseudoplastic non-Newtonian fluids.
Article
Engineering, Chemical
Dongdong Kang, Huiju Shao, Guijing Chen, Xiaoliang Dong, Shuhao Qin
Summary: The study investigates the effects of matrix miscibility on membrane microstructure during NIPS process, leading to the development of PVDF/SMANa ultrafiltration membranes with superior performance. This strategy holds promise for large-scale membrane manufacturing.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Chemistry, Physical
George M. Neville, Kerrie A. Morrison, Ella R. Shilliday, James Doutch, Robert Dalgliesh, Gareth J. Price, Karen J. Edler
Summary: This study investigates the effect of end group variations on the solution behavior of SMA copolymers synthesized using RAFT polymerization. It is found that the hydrophobicity and hydrophilicity of the end group influence the self-assembly and nanodisc formation of the copolymers.
Article
Materials Science, Multidisciplinary
Can Xu, Chuxuan Chen, Jing Jiang, Changwen Zhao, Yuhong Ma, Wantai Yang
Summary: This study reports a strategy to prepare monodisperse styrene-maleic anhydride-isoprene terpolymer microspheres via self-stabilized precipitation polymerization. The prepared microspheres have uniform particle sizes and narrow size distributions. The copolymerization proceeds in an alternating way between the electron donor and electron acceptor monomers, and isoprene is incorporated into the polymer chain through 1,4 addition. The gel fraction of microspheres varies with the feeding ratio of isoprene. The Diels-Alder reaction between maleic anhydride and isoprene can be effectively inhibited by adjusting the amount of initiator or polymerization temperature.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Shihui Li, Ling Cai, Dongmei Cui
Summary: The spontaneous alternating copolymerization of maleic anhydride (MA) and styrene (St) derivatives was investigated using various Lewis acids. With the presence of alkyl aluminum or butyl magnesium, MA-St alternating copolymers with ultra-high molecular weight (M-n <= 166.5x10(4)) and high glass transition temperature (211 degrees C <= T-g <= 216 degrees C) were obtained. The microstructure of the MA-St copolymers was analyzed by H-1 and C-13 NMR spectra. Additionally, the copolymerizations of MA with St derivatives were explored using AlOctyl(3) as an activator in toluene at 50 degrees C.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Chemistry, Physical
Eyup Basaran, Zeynep Demircioglu, Gonca Ozdemir Tari, Umit Ceylan, Aysegul Karakucuk-Iyidogan, Emine Elcin Oruc-Emre, Muhittin Aygun
Summary: In this study, an enantiomerically pure triazole derivative was successfully synthesized, characterized by spectroscopic techniques and X-ray diffraction, and analyzed for various computational properties and chemical activity descriptors. The stability of the molecule, arising from hyperconjugative interactions and charge delocalization, was examined through natural bond orbital analysis, and nonlinear optical properties were explored.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Biochemistry & Molecular Biology
Laurent Gavara, Alice Legru, Federica Verdirosa, Laurent Sevaille, Lionel Nauton, Giuseppina Corsica, Paola Sandra Mercuri, Filomena Sannio, Georges Feller, Remi Coulon, Filomena De Luca, Giulia Cerboni, Silvia Tanfoni, Giulia Chelini, Moreno Galleni, Jean-Denis Docquier, Jean-Francois Hernandez
Summary: Researchers are developing compounds based on the 1,2,4-triazole-3-thione scaffold to target resistance mechanisms in Gram-negative bacteria, with promising potential for broad-spectrum inhibitors. These compounds, particularly those containing a carboxylic group at the 4-position, have shown potent inhibition against VIM-type enzymes. Further exploration is needed to improve outer membrane penetration and efficacy against other carbapenemases.
BIOORGANIC CHEMISTRY
(2021)
Article
Chemistry, Physical
Jamelah S. Al-Otaibi, Y. Sheena Mary, Y. Shyma Mary, Nivedita Acharjee, Sreejit Soman
Summary: The chemical and electronic properties of an adamantane-thione derivative, ATT, were investigated experimentally and theoretically. Solvation energies in different solvents were predicted, and acetone was found to be a better solvent. The chemical descriptors of ATT decreased in the solution phase compared to the gas phase. Molecular dynamics simulations provided solvent accessible surface area values for unbound and bound structures of ATT. (c) 2022 Elsevier B.V. All rights reserved.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Review
Biochemistry & Molecular Biology
Majid M. Heravi, Pourya Mohammadi
Summary: Layered double hydroxides (LDHs) are utilized as efficient and eco-friendly catalysts in Suzuki, Heck, Sonogashira, and Ullmann cross-coupling reactions, leading to carbon-carbon bond formations.
MOLECULAR DIVERSITY
(2022)
Article
Engineering, Chemical
Ghazaleh Jahani, Masoume Malmir, Majid M. Heravi
Summary: A novel nitrogen- and sulfur-doped graphene carbon dot-modified magnetic nanocomposite was synthesized and characterized. The catalyst, Fe3O4/g-CSNCDs, showed excellent catalytic activity and selectivity in alcohol oxidation. The carbonation of reagents and magnetic nanoparticles were found to have an impact on the catalytic performance. The Fe3O4/g-CSNCDs catalyst not only exhibited recyclability and magnetic recovery, but also showed improved catalytic activity compared to the bare g-CSNCDs.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2022)
Review
Chemistry, Multidisciplinary
Heshmatollah Sepahvand, Majid M. Heravi, Mahyar Saber, Seyyed Emad Hooshmand
Summary: Enzymes play a key role in chemical industries as biological catalysts. Immobilization of enzymes using techniques like the Ugi multicomponent reaction can enhance their stability and activity, leading to a more robust catalyst system. Immobilized enzymes through Ugi MCR show good stability and activity, with the potential for synergistic effects on enzyme activities.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Majid M. Heravi, Reihaneh Malakooti, Kosar Kafshdarzadeh, Zahra Amiri, Vahideh Zadsirjan, Hassan Atashin
Summary: An eco-friendly method for the synthesis of substituted dihydropyrano[2,3-c]pyrazole and benzylpyrazolyl coumarin derivatives has been developed through a multicomponent reaction. The method offers wide scope, high yields, short reaction times, and simple workup procedure. Furthermore, the nanocatalyst used in this method can be easily recovered and reused multiple times without significant loss in catalytic activity and performance.
RESEARCH ON CHEMICAL INTERMEDIATES
(2022)
Review
Chemistry, Applied
Yalda Rangraz, Majid M. Heravi
Summary: The development of methodologies for carbon-nitrogen bond formation is crucial in organic synthesis, as the resulting products are widely used in pharmaceuticals, biologically active compounds, and natural products. Recently, nanosized metal catalysts have gained significant attention for their excellent catalytic performance, high product yields, mild reaction conditions, and environmental sustainability. This review provides an overview of the latest progress in the fabrication of nanocatalysts and their applications in constructing carbon-nitrogen bonds via cross-coupling reactions.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Reihaneh Malakooti, Majid M. Heravi, Zahra Amiri, Kosar Kafshdarzadeh, Vahideh Zadsirjan, Zeynab Parsaee
Summary: In this study, [Cu(bpdo)(2)center dot 2H(2)O](2+)/montmorillonite nanocomposite was successfully prepared and characterized. It exhibited efficient catalytic activity in the synthesis of 2-amino-4H-chromene and 2-amino-4H-benzopyran derivatives, as well as spirochromene and spiroacenaphthylene derivatives via multicomponent reactions. The method demonstrated advantages such as efficiency, rapidness, easy operation, high yields, recyclable catalyst, and environmentally friendly conditions.
RESEARCH ON CHEMICAL INTERMEDIATES
(2022)
Article
Multidisciplinary Sciences
Mansoureh Daraie, Masoud Mirzaei, Maryam Bazargan, Vadjiheh Sadat Amiri, Bita Abdolahi Sanati, Majid M. Heravi
Summary: A series of nanocatalysts containing different lanthanide elements were synthesized and evaluated for their catalytic performance in the synthesis of bioactive isatin derivatives, with nano-Gd-B2W22 showing superior catalytic activity.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Masoume Malmir, Majid M. Heravi, Zahra Yekke-Ghasemi, Masoud Mirzaei
Summary: Polyoxometalates (POMs) are efficient catalysts that can be used for a wide range of chemical transformations. In this study, two hybrid and heterogeneous Keggin catalysts, TBA-PW11 and TBA-SiW11, were reported. The catalytic performance of these catalysts was tested in the cyanosilylation reaction under solvent-free conditions. TBA-PW11 showed better catalytic efficiency than TBA-SiW11, possibly due to its higher Lewis acidity and easier accessibility of metal centers. The recyclability and heterogeneity of both catalysts were also examined, and they remained active after at least three recycling procedures.
SCIENTIFIC REPORTS
(2022)
Review
Chemistry, Organic
Majid M. Heravi, Batoul Alipour, Vahideh Zadsirjan, Masoume Malmir
Summary: The Robinson annulation is a significant reaction for the synthesis of alpha,beta-unsaturated ketone ring that involves the generation of two C-C bonds. It has been frequently used in the total synthesis of biologically active natural products. These products and their derivatives play a major role in pharmacotherapy, especially for cancer and infectious diseases.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Mahnaz Karrabi, Masoume Malmir, Elham Shafiei toran Poshti, Majid M. Heravi, Tayebeh Hosseinnejad
Summary: In this project, a new hybrid system composed of CuO incorporated onto functionalized-Mont was designed and prepared. The application of this hybrid system as a heterogeneous catalyst for the preparation of pyrazolopyranopyrimidines was investigated. Metal-ligand interactions in the complex model were described using quantum chemistry methods.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Masoume Malmir, Majid M. Heravi, Zahra Yekke-Ghasemi, Satar Saberi, Masoud Mirzaei
Summary: A new heterogeneous catalyst, TBA8[Zr(W5O18)2]middot17H2O (Zr(W5)2), was synthesized and characterized. It was found that the catalyst had a sandwich-type structure consisting of zirconium ions and mono-lacunary Lindqvist [W5O18 ]4- anions, encapsulated by TBA+ cations. This catalyst exhibited hydrophobic properties and improved catalytic efficiency by trapping reactants on its surface. Using Zr(W5)2 as a catalyst, a series of 1,5-benzodiazepines were successfully synthesized via mild and solvent-free reactions.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Applied
Masoume Malmir, Majid M. Heravi, Ghazaleh Jahani
Summary: Metal-organic frameworks (MOFs) are viable and environmentally friendly alternatives to traditional catalysts, and the magnetic Ox-CN-Cu-MOF catalyst has shown remarkable catalytic performance due to its unique structure and Lewis acidic properties. It also exhibits excellent recyclability.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Biotechnology & Applied Microbiology
Masoumeh Bagheri Bisafar, Masoume Malmir, Majid M. Heravi
Summary: In this study, a novel magnetic MOFs-based catalyst was synthesized and showed good catalytic activity and stability for the reduction of nitroarenes and organic dyes. The catalyst can be easily separated and recovered by magnetic separation, and it can be reused for multiple cycles.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Zahra Yekke-Ghasemi, Majid M. Heravi, Masoume Malmir, Masoud Mirzaei
Summary: In this study, a tri-component composite Zr/SiW12/GO was prepared using an ultrasonic-assisted method. This composite, acting as a remarkable heterogeneous catalyst, showed exceptional catalytic performance in the oxidation reaction of sulfides to sulfoxides. The composite also demonstrated exceptional stability and could be reused up to four times without significant loss in its catalytic activity.
SCIENTIFIC REPORTS
(2023)
Review
Chemistry, Multidisciplinary
Majid M. Heravi, Azadeh Nazari
Summary: Natural product synthesis is a constantly evolving field that evaluates new synthetic methods and reagents to address the complexities of structures and functions. SmI2, a widely-used reagent in chemical synthesis, has been highlighted in this review for its recent advances and strategies used in the total synthesis of natural products since 2004.