期刊
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 60
卷 60, 期 -, 页码 591-614出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev-pharmtox-010919-023253
关键词
neuromodulation; psychiatric disorders; devices; neural circuits
资金
- Intramural Research Program of the National Institute of Mental Health [ZIAMH002955]
- Brain & Behavior Research Foundation
- NATIONAL INSTITUTE OF MENTAL HEALTH [ZIAMH002955] Funding Source: NIH RePORTER
Device-based neuromodulation of brain circuits is emerging as a promising new approach in the study and treatment of psychiatric disorders. This work presents recent advances in the development of tools for identifying neurocircuits as therapeutic targets and in tools for modulating neurocircuits. We review clinical evidence for the therapeutic efficacy of circuit modulation with a range of brain stimulation approaches, including subthreshold, subconvulsive, convulsive, and neurosurgical techniques. We further discuss strategies for enhancing the precision and efficacy of neuromodulatory techniques. Finally, we survey cutting-edge research in therapeutic circuit modulation using novel paradigms and next-generation devices.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据