Unambiguous Intracellular Localization and Quantification of a Potent Iridium Anticancer Compound by Correlative 3D Cryo X-Ray Imaging

Intracellular localization of an osmocenyl-tamoxifen derivative in breast cancer cells revealed by synchrotron radiation X-ray fluorescence nanoimaging

(2019) Florin FUS et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Intracellular Chemistry: Integrating Molecular Inorganic Catalysts with Living Systems

(2018) Anh H. Ngo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Exploring the Effect of Polypyridyl Ligands on the Anticancer Activity of Phosphorescent Iridium(III) Complexes: From Proteosynthesis Inhibitors to Photodynamic Therapy Agents

(2018) Jitka Pracharova et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cyclometalated iridium(III) complexes for life science

(2018) Chiara Caporale et al.   COORDINATION CHEMISTRY REVIEWS

Reversible pH-Responsive Behavior of Ruthenium(II) Arene Complexes with Tethered Carboxylate

(2018) Francisco Martínez-Peña et al.   INORGANIC CHEMISTRY

Imaging of a clickable anticancer iridium catalyst

(2018) Xiuxiu Wang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action

(2018) Jessica M. Hearn et al.   Metallomics

Different approaches to modeling analysis of mitochondrial swelling

(2018) Sabzali Javadov et al.   MITOCHONDRION

Nanoscopic X-ray fluorescence imaging and quantification of intracellular key-elements in cryofrozen Friedreich’s ataxia fibroblasts

(2018) Björn De Samber et al.   PLoS One

Novel and Versatile Imine-N-Heterocyclic Carbene Half-Sandwich Iridium(III) Complexes as Lysosome-Targeted Anticancer Agents

(2018) Yuliang Yang et al.   INORGANIC CHEMISTRY

Lipid Droplets in Cancer: Guardians of Fat in a Stressful World

(2018) Toni Petan et al.   MOLECULES

Correlative 3D x-ray fluorescence and ptychographic tomography of frozen-hydrated green algae

(2018) Junjing Deng et al.   Science Advances

Structure-activity relationships for highly potent half-sandwich organoiridium(III) anticancer complexes with C^N-chelated ligands

(2018) Yuliang Yang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Efficient concentration of high-energy x-rays for diffraction-limited imaging resolution

(2017) Julio Cesar da Silva et al.   Optica

Unraveling heme detoxification in the malaria parasite by in situ correlative X-ray fluorescence microscopy and soft X-ray tomography

(2017) Sergey Kapishnikov et al.   Scientific Reports

Endoplasmic Reticulum-Localized Iridium(III) Complexes as Efficient Photodynamic Therapy Agents via Protein Modifications

(2016) Jung Seung Nam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multimodality hard-x-ray imaging of a chromosome with nanoscale spatial resolution

(2016) Hanfei Yan et al.   Scientific Reports

Cryo-soft X-ray tomography as a quantitative three-dimensional tool to model nanoparticle:cell interaction

(2016) Michele Chiappi et al.   JOURNAL OF NANOBIOTECHNOLOGY

Cyclometalated Iridium(III) Complexes as AIE Phosphorescent Probes for Real-Time Monitoring of Mitophagy in Living Cells

(2016) Chengzhi Jin et al.   Scientific Reports

Antioxidant Role for Lipid Droplets in a Stem Cell Niche of Drosophila

(2015) Andrew P. Bailey et al.   CELL

NanoSIMS analysis of an isotopically labelled organometallic ruthenium(ii) drug to probe its distribution and state in vitro

(2015) Ronald F. S. Lee et al.   CHEMICAL COMMUNICATIONS

Azide vs Alkyne Functionalization in Pt(II) Complexes for Post-treatment Click Modification: Solid-State Structure, Fluorescent Labeling, and Cellular Fate

(2015) Regina Wirth et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Contrasting Anticancer Activity of Half-Sandwich Iridium(III) Complexes Bearing Functionally Diverse 2-Phenylpyridine Ligands

(2015) Adam J. Millett et al.   ORGANOMETALLICS

MISTRAL: a transmission soft X-ray microscopy beamline for cryo nano-tomography of biological samples and magnetic domains imaging

(2015) Andrea Sorrentino et al.   JOURNAL OF SYNCHROTRON RADIATION

Organoiridium Complexes: Anticancer Agents and Catalysts

(2014) Zhe Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Potent Oxidant Anticancer Activity of Organoiridium Catalysts

(2014) Zhe Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism of cellular accumulation of an iridium(iii) pentamethylcyclopentadienyl anticancer complex containing a C,N-chelating ligand

(2014) Vojtech Novohradsky et al.   Metallomics

NanoSIMS combined with fluorescence microscopy as a tool for subcellular imaging of isotopically labeled platinum-based anticancer drugs

(2014) Anton A. Legin et al.   Chemical Science

Efficient Cisplatin Pro-Drug Delivery Visualized with Sub-100 nm Resolution: Interfacing Engineered Thermosensitive Magnetomicelles with a Living System

(2014) Elina A. Vitol et al.   Advanced Materials Interfaces

NanoSIMS multi-element imaging reveals internalisation and nucleolar targeting for a highly-charged polynuclear platinum compound

(2013) Louise E. Wedlock et al.   CHEMICAL COMMUNICATIONS

Cytoplasmic vacuolization during exposure to drugs and other substances

(2012) Toshihiko Aki et al.   CELL BIOLOGY AND TOXICOLOGY

Contrasting Reactivity and Cancer Cell Cytotoxicity of Isoelectronic Organometallic Iridium(III) Complexes

(2011) Zhe Liu et al.   INORGANIC CHEMISTRY

Organometallic Half-Sandwich Iridium Anticancer Complexes

(2011) Zhe Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Nonemissive Iridium(III) Complex That Specifically Lights-Up the Nuclei of Living Cells

(2011) Chunyan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visualising gold inside tumour cells following treatment with an antitumour gold(i) complex

(2011) Louise E. Wedlock et al.   Metallomics

Organometallic Iridium(III) Cyclopentadienyl Anticancer Complexes Containing C,N-Chelating Ligands

(2011) Zhe Liu et al.   ORGANOMETALLICS

Secondary necrosis: The natural outcome of the complete apoptotic program

(2010) Manuel T. Silva   FEBS LETTERS

Three-dimensional cellular ultrastructure resolved by X-ray microscopy

(2010) Gerd Schneider et al.   NATURE METHODS

Quantitative 3D elemental microtomography of Cyclotella meneghiniana at 400-nm resolution

(2010) M. D. de Jonge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell death: Insights into the ultrastructure of mitochondria

(2010) C. Ulivieri   TISSUE & CELL

Exploring the cellular accumulation of metal complexes

(2009) Cindy A. Puckett et al.   DALTON TRANSACTIONS

Cytotoxicity, Hydrophobicity, Uptake, and Distribution of Osmium(II) Anticancer Complexes in Ovarian Cancer Cells

(2009) Sabine H. van Rijt et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cryo-X-ray tomography of vaccinia virus membranes and inner compartments

(2009) José L. Carrascosa et al.   JOURNAL OF STRUCTURAL BIOLOGY

A soft X-ray beamline for transmission X-ray microscopy at ALBA

(2009) E. Pereiro et al.   JOURNAL OF SYNCHROTRON RADIATION

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY