A Fluorescent Probe for Rapid, High-Contrast Visualization of Folate-Receptor-Expressing Tumors In Vivo

Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease

(2018) Miles A. Miller et al.   CHEMICAL COMMUNICATIONS

MORAb-202, an antibody drug conjugate utilizing humanized anti-human FRa farletuzumab and the microtubule-targeting agent eribulin, has potent anti-tumor activity

(2018) Xin Cheng et al.   MOLECULAR CANCER THERAPEUTICS

A Novel Tumor-Specific Agent for Intraoperative Near-Infrared Fluorescence Imaging: A Translational Study in Healthy Volunteers and Patients with Ovarian Cancer

(2016) C. E. S. Hoogstins et al.   CLINICAL CANCER RESEARCH

Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors: a patent evaluation of US20160011199A1

(2016) Jean-Yves Winum   EXPERT OPINION ON THERAPEUTIC PATENTS

Development of background-free tame fluorescent probes for intracellular live cell imaging

(2016) Samira Husen Alamudi et al.   Nature Communications

Optimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression

(2015) Eunha Kim et al.   BIOCONJUGATE CHEMISTRY

IMGN853, a Folate Receptor-  (FR )-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FR -Expressing Tumors

(2015) O. Ab et al.   MOLECULAR CANCER THERAPEUTICS

Red Si–rhodamine drug conjugates enable imaging in GFP cells

(2014) Eunha Kim et al.   CHEMICAL COMMUNICATIONS

The folate receptor as a rational therapeutic target for personalized cancer treatment

(2014) Yehuda G. Assaraf et al.   DRUG RESISTANCE UPDATES

Development of Tumor-Targeted Near Infrared Probes for Fluorescence Guided Surgery

(2013) Lindsay E. Kelderhouse et al.   BIOCONJUGATE CHEMISTRY

Clinical recognition and aspects of the cerebral folate deficiency syndromes

(2013) Vincent Ramaekers et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Structural basis for molecular recognition of folic acid by folate receptors

(2013) Chen Chen et al.   NATURE

Targeted zwitterionic near-infrared fluorophores for improved optical imaging

(2013) Hak Soo Choi et al.   NATURE BIOTECHNOLOGY

A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins

(2013) Gražvydas Lukinavičius et al.   Nature Chemistry

Image-guided cancer surgery using near-infrared fluorescence

(2013) Alexander L. Vahrmeijer et al.   Nature Reviews Clinical Oncology

Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results

(2011) Gooitzen M van Dam et al.   NATURE MEDICINE

Folate-Targeted Therapies for Cancer

(2010) Wei Xia et al.   JOURNAL OF MEDICINAL CHEMISTRY

Folate-targeted therapeutic and imaging agents for cancer

(2009) Philip Stewart Low et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Folate receptor alpha as a tumor target in epithelial ovarian cancer

(2008) Kimberly R. Kalli et al.   GYNECOLOGIC ONCOLOGY

Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes

(2008) Yasuteru Urano et al.   NATURE MEDICINE

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY