期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 59, 期 12, 页码 4937-4941出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201914354
关键词
[4+2] cycloaddition; asymmetric catalysis; dirhodium; vinylcarbenes
资金
- National Science Foundation [CHE 1531620, CHE 1626172]
The reaction of 2-siloxycyclo-1,3-dienes with E-vinyldiazoacetates in the presence of the bulky chiral dirhodium tetracarboxylate catalyst, Rh-2(R-p-PhTPCP)(4) results in an enantioselective [4+2] cycloaddition, in which three new stereogenic centers are formed. The [4+2] cycloadducts are generated as single diastereomers with high enantiocontrol (95-98 % ee). When the diene contains an additional stereogenic center, effective kinetic resolution can be achieved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据