1,3-Difunctionalizations of [1.1.1]Propellane via 1,2-Metallate Rearrangements of Boronate Complexes

Synthesis of Enantioenriched α-Chiral Bicyclo[1.1.1]pentanes

(2019) Marie L. J. Wong et al.   ORGANIC LETTERS

Reactions of 2-Aryl-1,3-Dithianes and [1.1.1]Propellane

(2019) Nisalak Trongsiriwat et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aminoalkylation of [1.1.1]Propellane Enables Direct Access to High-Value 3-Alkylbicyclo[1.1.1]pentan-1-amines

(2019) Jonathan M. E. Hughes et al.   ORGANIC LETTERS

A General Route to Bicyclo[1.1.1]pentanes through Photoredox Catalysis

(2019) Jeremy Nugent et al.   ACS Catalysis

Synthesis and applications of highly functionalized 1-halo-3-substituted bicyclo[1.1.1]pentanes

(2018) Dimitri F. J. Caputo et al.   Chemical Science

A General Amino Acid Synthesis Enabled by Innate Radical Cross-Coupling

(2018) Phil S. Baran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of BCP Benzylamines From 2-Azaallyl Anions and [1.1.1]Propellane

(2018) Russell A. Shelp et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonconjugated Hydrocarbons as Rigid-Linear Motifs: Isosteres for Material Sciences and Bioorganic and Medicinal Chemistry

(2018) Gemma M. Locke et al.   CHEMISTRY-A EUROPEAN JOURNAL

Branch-Selective Addition of Unactivated Olefins into Imines and Aldehydes

(2018) Jeishla L. M. Matos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Advances in the Synthetic Chemistry of Bicyclo[1.1.1]pentane

(2018) Junichiro Kanazawa et al.   SYNLETT

Copper-Catalyzed Enantioselective Hydroboration of Unactivated 1,1-Disubstituted Alkenes

(2017) Won Jun Jang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Merging Photoredox with 1,2-Metallate Rearrangements: The Photochemical Alkylation of Vinyl Boronate Complexes

(2017) Mattia Silvi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Conjunctive Cross-Coupling between Grignard-Derived Boron “Ate” Complexes and C(sp2) Halides or Triflates: NaOTf as a Grignard Activator and Halide Scavenger

(2017) Gabriel J. Lovinger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical Multicomponent Carboamination of [1.1.1]Propellane

(2017) Junichiro Kanazawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Functionalized Alkenes by a Transition-Metal-Free Zweifel Coupling

(2017) Roly J. Armstrong et al.   ORGANIC LETTERS

50 Years of Zweifel Olefination: A Transition-Metal-Free Coupling

(2017) Varinder Aggarwal et al.   SYNTHESIS-STUTTGART

Toward Resolving the Resveratrol Conundrum: Synthesis and in Vivo Pharmacokinetic Evaluation of BCP–Resveratrol

(2017) Yi Ling Goh et al.   ACS Medicinal Chemistry Letters

Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space

(2016) Nicholas A. Meanwell   CHEMICAL RESEARCH IN TOXICOLOGY

A practical metal-free homolytic aromatic alkylation protocol for the synthesis of 3-(pyrazin-2-yl)bicyclo[1.1.1]pentane-1-carboxylic acid

(2016) Navanita T. Thirumoorthi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Strain-release amination

(2016) R. Gianatassio et al.   SCIENCE

Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA2 Inhibitor

(2016) Nicholas D. Measom et al.   ACS Medicinal Chemistry Letters

Expedient synthesis of 3-phenylbicyclo[1.1.1]pentan-1-amine via metal-free homolytic aromatic alkylation of benzene

(2015) Navanita T. Thirumoorthi et al.   CHEMICAL COMMUNICATIONS

Stereospecific Coupling of Boronic Esters with N-Heteroaromatic Compounds

(2015) Josep Llaveria et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Assembly-line synthesis of organic molecules with tailored shapes

(2014) Matthew Burns et al.   NATURE

Enantiospecific sp2–sp3 coupling of secondary and tertiary boronic esters

(2014) Amadeu Bonet et al.   Nature Chemistry

Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

(2012) Antonia F. Stepan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Scalable Synthesis of 1-Bicyclo[1.1.1]pentylamine via a Hydrohydrazination Reaction

(2011) Kevin D. Bunker et al.   ORGANIC LETTERS