Review
Public, Environmental & Occupational Health
Lucy Ngaihbanglovi Pachuau, Caterina Tannous, Mansi Vijaybhai Dhami, Kingsley Emwinyore Agho
Summary: This study conducted a systematic review on the risk behaviors associated with HIV infection among HIV positive people who inject drugs (PWID) in India. The results showed significant injecting and sexual risk behaviors among HIV positive PWID in India, with increasing HIV transmission among PWID in different states, particularly in the northeastern states and metropolitan cities. It is important to conduct more studies in other regions of the country to understand the true burden of the disease.
Article
Public, Environmental & Occupational Health
Amobi Onovo, Abiye Kalaiwo, Moses Katbi, Otse Ogorry, Antoine Jaquet, Olivia Keiser
Summary: This study measured HIV seroprevalence among MSM and PWID in Nigeria and identified clustered distribution of HIV infection among them. The results showed increased HIV seroprevalence among PWID and a substantial decrease among MSM compared to a previous survey, highlighting geographical areas to prioritize for control of HIV infection. Geographical information system technology was found to be a useful tool to inform public health planning for interventions targeting epidemic control of HIV infection.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2021)
Article
Multidisciplinary Sciences
Ashwin Belludi, Allison M. McFall, Sunil Suhas Solomon, David D. Celentano, Shruti H. Mehta, A. K. Srikrishnan, M. Suresh Kumar, Suniti Solomon, Gregory M. Lucas
Summary: The study in India revealed low awareness but high willingness to use PrEP among PWID and MSM. Common reasons for unwillingness to use PrEP included perceived low risk of HIV infection, fear of being labeled as HIV-positive, and concerns about side effects. Key factors associated with increased willingness to use PrEP included sharing needles and hazardous alcohol use among PWID, and having a main male partner and injection drug use among MSM.
Article
Immunology
Steven J. Clipman, Sunil S. Solomon, Aylur K. Srikrishnan, Allison M. McFall, Selvamurthi Gomathi, Shanmugam Saravanan, Santhanam Anand, Canjeevaram K. Vasudevan, Muniratnam S. Kumar, David D. Celentano, Shruti H. Mehta, Gregory M. Lucas
Summary: Drug resistance testing is limited in HIV care in India. Prevalent drug resistance mutations are more common among MSM and PWID. Drug resistance is more common in nucleoside and nonnucleoside reverse transcriptase inhibitors, and more prevalent among MSM.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Article
Immunology
Shelley N. Facente, Sheena Patel, Jennifer Hecht, Erin Wilson, Willi McFarland, Kimberly Page, Peter Vickerman, Hannah Fraser, Katie Burk, Meghan D. Morris
Summary: In San Francisco, young people who inject drugs, men who have sex with men and inject drugs, and low-income trans women have relatively high rates of HCV diagnosis, but there is an urgent need to increase treatment initiation, especially among young people who inject drugs.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Public, Environmental & Occupational Health
Tsz Ho Kwan, Bonnie Chun Kwan Wong, Ka Hing Wong, Shui Shan Lee
Summary: People living with human immunodeficiency virus (PLHIV) are at a higher risk of hepatitis C virus (HCV) co-infection. This study examines the epidemiologic features of HIV/HCV co-infection in men who have sex with men (MSM) and non-MSM. The findings show significant differences between the two groups, which can inform intervention strategies.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Medicine, General & Internal
Kenneth H. Mayer, LaRon Nelson, Lisa Hightow-Weidman, Matthew J. Mimiaga, Leandro Mena, Sari Reisner, Demetre Daskalakis, Steven A. Safren, Chris Beyrer, Patrick S. Sullivan
Summary: Men who have sex with men (MSM) in the USA face ongoing high risk of HIV acquisition, with factors including role versatility, biological, individual, social, and structural elements affecting the epidemic. Racial and ethnic minority men may be further concentrated in high-prevalence networks due to assortative mixing and adverse life experiences. Young MSM have additional HIV risks due to impulse control issues and lack of familiarity with serostatus discussions, while digital technologies could be beneficial for prevention efforts. Older and transgender MSM also face unique challenges requiring tailored HIV prevention information and culturally responsive programmes. Training of healthcare providers in culturally competent care is essential for optimizing HIV care and prevention.
Article
Immunology
Ying Guo, Xiaojie Huang, Xintong Sun, Yixi Yu, Yan Wang, Baojin Zhang, Jie Cao, Shuo Wen, Yuchen Li, Xin Wang, Siyu Cai, Wei Xia, Feili Wei, Junyi Duan, Haozhi Dong, Shan Guo, Fengqiu Zhang, Dongxiang Zheng, Zheng Sun
Summary: The study aimed to investigate salivary virome composition and functional genes in HIV-negative and -positive MSM individuals. Results showed that salivary virobiota composition in individuals with mild immunosuppression was most similar to that in healthy individuals, while severe immunosuppression resulted in suppressed virus genera. Analysis revealed changes in KEGG Pathways related to HIV progression, immune function, and oral health in different HIV infection stages.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Medicine, General & Internal
Wilson M. Compton, Christopher M. Jones
Summary: Among men who have sex with men, bisexual men have a higher rate of substance use compared to other subgroups, and methamphetamine use is associated with high-risk sexual behaviors and HIV transmission.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Clinical Neurology
Sara N. Levintow, Brian W. Pence, Kimberly A. Powers, Alexander Breskin, Teerada Sripaipan, Tran Viet Ha, Viet Anh Chu, Vu Minh Quan, Carl A. Latkin, Vivian F. Go
Summary: The study found that severe depressive symptoms decreased the cumulative incidence of ART initiation among PWID living with HIV, but had no significant impact on viral suppression. Future research should further investigate the antagonistic effect of depression on treatment uptake in order to improve HIV clinical outcomes and reduce transmission among PWID.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Multidisciplinary Sciences
Lucy Ngaihbanglovi Pachuau, Caterina Tannous, Richard Lalramhluna Chawngthu, Kingsley Emwinyore Agho
Summary: This study aimed to estimate the prevalence and associated factors of HIV among people who inject drugs (PWID) in Mizoram, Northeast India. The study found a high prevalence of HIV among PWID, with positive associations observed in females, those over 35 years old, married, divorced/separated/widowed individuals, and those who shared needles/syringes. The use of condoms and reduced alcohol consumption were found to be related to a lower risk of HIV infection.
Article
Immunology
Cassie G. Ackerley, S. Abigail Smith, Phillip M. Murray, Praveen K. Amancha, Robert A. Arthur, Zhengyi Zhu, Ann Chahroudi, Rama R. Amara, Yi-Juan Hu, Colleen F. Kelley
Summary: Young men who have sex with men (YMSM) in the US are at a particularly high risk for HIV acquisition. This could be attributed to differences in the rectal mucosal immune environment associated with earlier sexual debut and less lifetime exposure to receptive anal intercourse. Additionally, the microbiome composition of YMSM is enriched for anaerobic bacteria associated with HIV acquisition risk.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Pedro Mateu-Gelabert, Nasim S. Sabounchi, Honoria Guarino, Courtney Ciervo, Kellie Joseph, Benjamin J. Eckhardt, Chunki Fong, Shashi N. Kapadia, Terry T. K. Huang
Summary: Injection drug use is the main risk factor for hepatitis C virus transmission in the U.S., particularly among young people who inject drugs (YPWID). This study found that around one-third of YPWID in New York City had been exposed to HCV, with certain risk factors such as sharing drug paraphernalia, long-term drug use, homelessness, and multiple incarcerations significantly associated with HCV status. A qualitative system dynamics model was developed to better understand how these risk factors interact and inform potential interventions for reducing HCV infections.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Sonjelle Shilton, Ketevan Stvilia, Maia Japaridze, Nino Tsereteli, Dali Usharidze, Shota Phevadze, Miranda Jghenti, Antons Mozalevskis, Jessica Markby, Niklas Luhmann, Cheryl Johnson, Pamela Nabeta, Stefano Ongarello, Elena Ivanova Reipold, Amiran Gamkrelidze
Summary: This study aims to improve the access and uptake of HCV testing through an online program delivering HCV self-testing kits to homes in Georgia. The study will compare different delivery methods and evaluate the feasibility, acceptability, and cost of HCV testing among men who have sex with men and people who inject drugs.
Article
Public, Environmental & Occupational Health
Suraj Pal, Praveen Kumar Pathak, Margubur Rahaman
Summary: This study explores the association between physical-mental well-being and awareness of HIV/STIs among Men who have Sex with Men in India. The findings indicate that a significant proportion of respondents suffer from long-term and short-term illnesses, disordered eating behavior, mood swings, and suicidal thoughts. Additionally, there is a lack of awareness regarding STIs and preventive measures for HIV/AIDS among this population. Therefore, there is a need to strengthen sexual and reproductive health education and improve healthcare services to reduce the vulnerability to HIV/STIs among Men who have Sex with Men.
Article
Immunology
Javier A. Cepeda, Sunil S. Solomon, Aylur K. Srikrishnan, Allison M. McFall, Muniratnam Suresh Kumar, Canjeevaram K. Vasudevan, Santhanam Anand, David D. Celentano, Gregory M. Lucas, Shruti H. Mehta
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
(2017)
Article
Immunology
Kerry M. Sheets, Mohamed G. Atta, Derek M. Fine, Katie Zook, Allison M. Mcfall, Michelle M. Estrella, George J. Schwartz, Gregory M. Lucas
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
(2017)
Article
Gastroenterology & Hepatology
S. S. Solomon, M. S. Sulkowski, P. Amrose, A. K. Srikrishnan, A. M. McFall, B. Ramasamy, M. S. Kumar, S. Anand, D. L. Thomas, S. H. Mehta
JOURNAL OF VIRAL HEPATITIS
(2018)
Article
Multidisciplinary Sciences
Bushra Sabri, Allison M. McFall, Sunil S. Solomon, Aylur K. Srikrishnan, Canjeevaram K. Vasudevan, Santhanam Anand, David D. Celentano, Shruti H. Mehta, Suresh Kumar, Gregory M. Lucas
Article
Medicine, General & Internal
Sunil S. Solomon, Allison M. McFall, Gregory M. Lucas, Aylur K. Srikrishnan, Muniratnam S. Kumar, Santhanam Anand, Thomas C. Quinn, David D. Celentano, Shruti H. Mehta
Article
Public, Environmental & Occupational Health
Cecilia Tomori, Allison M. McFall, Sunil S. Solomon, Aylur K. Srikrishnan, Santhanam Anand, P. Balakrishnan, Shruti H. Mehta, David D. Celentano
SOCIAL SCIENCE & MEDICINE
(2018)
Article
Multidisciplinary Sciences
Ramnath Subbaraman, Beena E. Thomas, Senthil Sellappan, Chandra Suresh, Lavanya Jayabal, Savari Lincy, Agnes L. Raja, Allison McFall, Sunil Suhas Solomon, Kenneth H. Mayer, Soumya Swaminathan
Letter
Gastroenterology & Hepatology
Sunil Suhas Solomon, Allison M. McFall, Gregory M. Lucas, Shruti H. Mehta
JOURNAL OF HEPATOLOGY
(2020)
Article
Gastroenterology & Hepatology
Sunil Suhas Solomon, Thomas C. Quinn, Suniti Solomon, Allison M. McFall, Aylur K. Srikrishnan, Vinita Verma, Muniratnam S. Kumar, Oliver Laeyendecker, David D. Celentano, Syed H. Iqbal, Santhanam Anand, Canjeevaram K. Vasudevan, Shanmugam Saravanan, David L. Thomas, Kuldeep Singh Sachdeva, Gregory M. Lucas, Shruti H. Mehta
JOURNAL OF HEPATOLOGY
(2020)
Article
Immunology
Allison M. McFall, Neia Prata Menezes, Aylur K. Srikrishnan, Sunil S. Solomon, Santhanam Anand, Jiban J. Baishya, Gregory M. Lucas, David D. Celentano, Shruti H. Mehta
Summary: The COVID-19 pandemic has had a significant impact on HIV-related service utilization among MSM and PWID in India, potentially leading to increased transmission of HIV and more advanced disease presentations among these key populations.
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
(2022)
Article
Health Policy & Services
Neia S. Prata Menezes, Sunil S. Solomon, Allison M. Mcfall, Aylur K. Srikrishnan, Canjeevaram K. Vasudevan, M. Suresh Kumar, David D. Celentano, Shruti H. Mehta, Gregory M. Lucas
Summary: Monitoring the progress of key populations towards the UNAIDS 90-90-90 targets is crucial for controlling the HIV/AIDS epidemic. A study in India showed that men who have sex with men (MSM) had significant improvements in the HIV care continuum compared to people who inject drugs (PWID).
AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV
(2023)
Article
Substance Abuse
M. Kumi Smith, Sunil S. Solomon, Derek A. T. Cummings, Aylur K. Srikrishnan, M. Suresh Kumar, C. K. Vasudevan, Allison M. McFall, Gregory M. Lucas, David D. Celentano, Shruti H. Mehta
INTERNATIONAL JOURNAL OF DRUG POLICY
(2018)
Article
Substance Abuse
Eshan U. Patel, Sunil S. Solomon, Allison M. McFall, Aylur K. Srikrishnan, Amrose Pradeep, Paneerselvam Nandagopal, Oliver Laeyendecker, Aaron A. R. Tobian, David L. Thomas, Mark S. Sulkowski, M. Suresh Kumar, Shruti H. Mehta
INTERNATIONAL JOURNAL OF DRUG POLICY
(2018)
Article
Substance Abuse
Allison M. McFall, Sunil S. Solomon, Greg M. Lucas, David D. Celentano, Aylur K. Srikrishnan, Muniratnam S. Kumar, Shruti H. Mehta
Article
Public, Environmental & Occupational Health
Cecilia Tomori, Allison M. McFall, Aylur K. Srikrishnan, Shruti H. Mehta, Sunil S. Solomon, Santhanam Anand, Canjeevaram K. Vasudevan, Suniti Solomon, David D. Celentano