Article
Chemistry, Multidisciplinary
Xin Yang, Xinyue Li, Junyang Jin, Junchi Ma, Jinghua Liu, Zongfu An
Summary: The article reports a direct observation method for the detection of aflatoxin B-1 using liquid crystals. The method is highly selective and sensitive, allowing for detection of the toxin in complex samples such as corn and rice powder. Additionally, the method shows high selectivity and sensitivity for other toxins and common molecules in food.
Article
Chemistry, Physical
Saroj K. Parida, Debasis Behera, Sridhar Sahu
Summary: This study investigated the quantum chemical parameters of the liquid crystal 4-cyano-4-pentylbiphenyl with water molecule, including electron transfer and polarizability calculations. Results showed that a considerable amount of electron population was transferred from 4-cyano-4-pentylbiphenyl to the water molecule, indicating strong electron attraction between the two molecules.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Analytical
Zahra Khoshbin, Hamed Zahraee, Javad Zamanian, Asma Verdian, Mohammad Ramezani, Mona Alibolandi, Khalil Abnous, Seyed Mohammad Taghdisi
Summary: We developed an aptasensing array based on liquid crystal for monitoring tobramycin antibiotic. The direction of liquid crystal molecules changed from vertical to random due to the specific aptamer's conformational changes, indicating the presence of tobramycin. The aptasensor has the advantages of a wide linear concentration range, low limit of detection, and successful determination of tobramycin in milk and chicken egg samples.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Physical
Tahir D. Ibragimov
Summary: In the study, it was found that incorporating fullerenes into liquid crystal results in a decrease in clearing temperature and order parameter, affecting dielectric permittivity. Additionally, the inclusion of fullerenes also affects electric conductivity, elastic constant, rotational viscosity, and switching times.
FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES
(2021)
Article
Chemistry, Analytical
Duy Khiem Nguyen, Chang-Hyun Jang
Summary: The LC-based aptasensor developed in this study showed high specificity and a low detection limit for malathion, and was successfully applied to environmental samples. The sensor provides a simple, rapid, and convenient platform for label-free monitoring of malathion.
Article
Chemistry, Physical
Sulayman A. Oladepo
Summary: This study investigated the fluorescence emission properties of 5CB and 6CB liquid crystals and their variations with temperature. The results showed different fluorescence intensities and wavelengths at different temperatures for both liquid crystals, with significant changes observed during phase transitions. The temperature-dependent spectral evolutions provide insights into the excimer conformations and molecular behaviors of the liquid crystals.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Multidisciplinary
Sayani Das, Przemyslaw Kula, Susanta Sinha Roy
Summary: This study reported a novel application of LC in an optical aptasensor for the sensitive detection of amoxycillin antibiotic. The developed biosensor showed a low limit of detection and high specificity, and was successfully used to detect amoxycillin in tap water and lake water samples.
Proceedings Paper
Optics
Muhamad Safuan Mat Yeng, Shahrul Kadri Ayop
Summary: This study quantifies the optical stiffness of a single 4-Cyano-4-Pentylbiphenyl (5CB) microdroplet trapped in water using optical tweezers, considering factors such as droplet size and trapping power density. It is significant for potential applications of 5CB microdroplets in microactuators and sensing.
OPTICAL MANIPULATION AND STRUCTURED MATERIALS CONFERENCE (OMC 2022)
(2022)
Article
Chemistry, Multidisciplinary
Dong Yoon Jeon, Chang-Hyun Jang
Summary: We developed a liquid crystal-based immunosensor for the detection of anti-SARS-CoV-2 nucleocapsid protein antibodies. The alignment of liquid crystal molecules on anisotropic gold nanostructures was utilized to detect the antigen-antibody reaction. The sensor showed high sensitivity to the antibody changes compared to control proteins and could detect with a small sample volume.
Article
Thermodynamics
Sana Enomoto, Miyu Umeda, Taro Yamamoto, Ewa Juszynska-Galazka, Yuji Miyazaki, Hal Suzuki
Summary: The polymorphism and thermodynamic properties of 4-cyano-3-fluorophenyl 4-pentylbenzoate were studied using adiabatic calorimetry, differential scanning calorimetry (DSC), simultaneous X-ray diffractometry and DSC (XRD-DSC), and polarized optical microscopy (POM). Seven phases were identified, including a nematic phase, glass of the nematic phase, and four crystal phases. The thermodynamic stabilities of the phases were determined, and solid-solid phase transitions and crystallization kinetics were observed.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2023)
Article
Engineering, Electrical & Electronic
Pham Thi Kim Hong, Chang-Hyun Jang
Summary: A label-free LC aptasensor was developed to detect OTA based on the change in LCs orientation. The sensor has a linear detection range from 1 to 100 ng mL(-1) with a low limit of detection of 0.9 ng mL(-1). It can effectively detect OTA in grape juice and wine with high recovery and accuracy, showing advantages of high specificity, fast response, low cost, and simple fabrication.
IEEE SENSORS JOURNAL
(2021)
Review
Materials Science, Multidisciplinary
Deepak Devadiga, T. N. Ahipa
Summary: The review highlights the diverse applications of 4-Cyano-4 '-alkylbiphenyl (nCB) and other liquid crystal materials in advanced photonic materials and electro-optical devices beyond traditional display applications. It emphasizes the molecular structure, synthesis, crystal data, and liquid crystal properties of various nCB materials. Furthermore, the latest applications of nCB materials in sensors, smart windows, liquid crystal lenses, PV cells, supercapacitors, and drug delivery have been extensively covered in the review.
MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS
(2022)
Article
Chemistry, Analytical
Jin Zhang, Dianping Tang
Summary: A one-step aptasensing protocol based on 4-NP-loaded MMSNs was developed for the spectrometric determination of CEA, showing good linear relationship and high specificity for analyzing human serum specimens.
Article
Chemistry, Multidisciplinary
Praveen Kumar Singh, Himanshu Verma, Prashant Dubey, Roman Dabrowski, Ravindra Dhar
Summary: Graphene oxide dispersed nanocomposites show increased transition temperatures, enthalpies, and order parameters. Graphene oxide has an increased optical band gap, while reduced graphene oxide has a decreased optical band gap. The dielectric anisotropy is increased for graphene oxide dispersed nanocomposites, while the opposite property is observed for reduced graphene oxide dispersed system. The relaxation frequency has increased for graphene oxide dispersed system, while remaining unchanged for reduced graphene oxide dispersed system. Conductivity has increased by three orders of magnitude for reduced graphene oxide dispersed nanocomposites, but has decreased for graphene oxide dispersed system. Both GO/rGO dispersed systems show a decrease in threshold voltage, elastic constant, and rotational viscosity. The graphene oxide dispersed nanocomposite seems to be more effective due to its enhanced molecular polarizability.
Article
Chemistry, Multidisciplinary
Praveen Kumar Singh, Prashant Dubey, Ravindra Dhar, Roman Dabrowski
Summary: In this study, a small concentration of reduced graphene oxide was dispersed in the liquid crystalline media. The thermodynamic study showed a reduction in the transition temperature, enthalpy, and entropy of the dispersed nanocomposite. Optical study revealed a decrease in the optical bandgap of the dispersed nanocomposite compared to the pure sample. Dielectric spectroscopic measurement showed a decrease in dielectric anisotropy and an increase in ionic conductivity for the dispersed nanocomposite. The activation energy for DC conductivity was reduced in the dispersed nanocomposite, leading to an increase in conductivity. The cut-off region of DC conductivity also increased in the dispersed nanocomposite. Electro-optical studies indicated a reduction in the threshold voltage, splay elastic constant, and rotational viscosity for the dispersed nanocomposite.
Article
Biochemical Research Methods
Saranya Krishnan, Shina Sasi, Preshobha Kodakkattumannil, Salima Al Senaani, Geetha Lekshmi, Martin Kottackal, Khaled M. A. Amiri
Summary: This study aimed to develop an efficient DNA extraction protocol suitable for diverse plant species and tissues. A reliable and consistent protocol was described for the extraction of high-quality DNA from difficult-to-extract plant species. The optimized protocol was successful in extracting high-quality DNA from various plant species and tissues, making it useful for genomic studies of recalcitrant plants.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Eisaku Hokazono, Saori Fukumoto, Takeshi Uchiumi, Susumu Osawa
Summary: This study proposes a method for detecting nucleic acid amplification using pyrophosphate, which requires only two reagents and an automated analyzer. The technique has high sensitivity and reproducibility, and can detect pyrophosphate within 10 minutes. Therefore, this method has the potential to be a new, rapid, and simple detection technique for amplified nucleic acids.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Drew S. Sowersby, L. Kevin Lewis
Summary: SURE electrophoresis is a new method for concentrating samples in gels, which allows efficient detection of highly dilute DNA samples. This approach generates single bands with enhanced signal intensities and minimal band broadening.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Hongyi Liang, Guoliang Yin, Guangxi Shi, Zhiyong Liu, Xiaofei Liu, Jingwei Li
Summary: The mechanism of Echinacoside (ECH) in treating breast cancer (BC) was explored through network pharmacology and experimental validation. It was found that ECH plays an important role in anti-BC by regulating the PI3K/AKT/HIF-1 alpha/VEGF signaling pathway, and it exhibits multi-target and multi-pathway effects.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Daniel S. Kantner, Emily Megill, Anna Bostwick, Vicky Yang, Carmen Bekeova, Alexandria Van Scoyk, Erin L. Seifert, Michael W. Deininger, Nathaniel W. Snyder
Summary: This study compared the results of different methods for measuring the amount of acetyl-Coenzyme A. The colorimetric ELISA kit did not produce interpretable results, while the fluorometric enzymatic kit showed comparable results to the LC-MS-based methods depending on the matrix and extraction conditions. LC-MS/MS and LC-HRMS methods produced well-aligned results, especially when using stable isotope-labeled internal standards.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Jingyan Xu, Hanying Tan, Xionghui Ma, Linjing Su, Zhi Zhang, Yuhao Xiong
Summary: This study investigates the co-catalytic capabilities of MoO3 nanosheets in enhancing the enzyme-like catalytic activity of a two-dimensional ultrathin Fe(III)-modified covalent triazine framework (Fe-CTF) under neutral pH conditions. The Fe-CTF/MoO3 co-catalytic system exhibits enzyme-mimicking activity and enables the development of a colorimetric method for glucose detection. Furthermore, a straightforward one-pot colorimetric method is established for screening XOD inhibitors.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Lichao Zhang, Kang Xiao, Xueting Wang, Liang Kong
Summary: A novel fusion technology was designed to identify FAD-binding sites, achieving the best results on two independent test datasets and outperforming existing methods significantly. The high performance and certainty of the method were demonstrated through statistical tests and cross-entropy loss analysis.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Abdulkadir Kilic, Mehmet Aslan, Abdulkadir Levent
Summary: This study developed a simple, rapid, sensitive, and selective voltammetric technique for the electrochemical characterization and detection of the highly risky drug Edoxaban. The optimized voltammetric method showed good analytical working range and was successfully applied to urine and tablet samples.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Su Hyun Kim, Nara Shin, Jong-Min Jeon, Jeong-Jun Yoon, Jeong Chan Joo, Hee Taek Kim, Shashi Kant Bhatia, Yung-Hun Yang
Summary: To address environmental issues caused by traditional plastics, bioplastics have gained attention as alternatives. Although bioplastics have better degradability, their degradation still takes longer than anticipated. This study proposes a novel screening method to identify bioplastic degraders faster, saving time and providing more quantitative data.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Irem Okman Kocoglu, Pinar Esra Erden, Esma Kilic
Summary: In this study, an electrochemical biosensor based on carbon nanofibers and ionic liquid modification was constructed for tyramine detection. The biosensor showed linear response, low detection limit, high sensitivity, and exhibited good reproducibility, stability, and anti-interference ability.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Liana U. Akhmetzianova, Timur M. Davletkulov, Assol R. Sakhabutdinova, Alexey Chemeris, Irek M. Gubaydullin, Ravil R. Garafutdinov
Summary: A new program called LAMPrimers iQ has been developed for high-quality LAMP primer design, and its advantages in providing higher specificity and reliable detection of viral RNA were validated using SARS-CoV-2 coronavirus RNA as a model target.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Tommaso Pileri, Alberto Sinibaldi, Agostino Occhicone, Norbert Danz, Elena Giordani, Matteo Allegretti, Frank Sonntag, Peter Munzert, Patrizio Giacomini, Francesco Michelotti
Summary: This study developed a biosensing device based on one-dimensional photonic crystal to detect HER2 in breast cancer. The device combines label-free and fluorescence operation modes, allowing for real-time and accurate detection in less than 20 minutes. It offers a promising technique for combined label-free and fluorescence detection in disease diagnosis and therapeutic monitoring.
ANALYTICAL BIOCHEMISTRY
(2024)