Development and characterization of an inducible Dicer conditional knockout mouse model of Parkinson’s disease: validation of the antiparkinsonian effects of a sigma-1 receptor agonist and dihydromyricetin

Dysregulation of miRNA and its potential therapeutic application in schizophrenia

(2018) Ting Cao et al.   CNS Neuroscience & Therapeutics

JNK-mediated microglial DICER degradation potentiates inflammatory responses to induce dopaminergic neuron loss

(2018) Qing Wang et al.   Journal of Neuroinflammation

Detecting Alpha Synuclein Seeding Activity in Formaldehyde-Fixed MSA Patient Tissue by PMCA

(2018) Katelyn Becker et al.   MOLECULAR NEUROBIOLOGY

Parkinson's disease: A review

(2018) Vinay Goyal et al.   NEUROLOGY INDIA

miRNA-3473b contributes to neuroinflammation following cerebral ischemia

(2018) Xiaoyu Wang et al.   Cell Death & Disease

Recent Update on the Pharmacological Effects and Mechanisms of Dihydromyricetin

(2018) Jingyao Zhang et al.   Frontiers in Pharmacology

Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain

(2017) Diana Varol et al.   IMMUNITY

Activation of AMPK/mTORC1-Mediated Autophagy by Metformin Reverses Clk1 Deficiency-Sensitized Dopaminergic Neuronal Death

(2017) Qiuting Yan et al.   MOLECULAR PHARMACOLOGY

Dihydromyricetin protects against cerebral ischemia/reperfusion injury via suppressing microglia-mediated neuroinflammation and activation of ERK1/2-CREB signaling pathway

(2017) Yafei Zhao et al.   Journal of Functional Foods

Dicer and microRNAs protect adult dopamine neurons

(2017) Piotr Chmielarz et al.   Cell Death & Disease

The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission

(2017) Danielle O. Sambo et al.   Nature Communications

Dihydromyricetin protects neurons in an MPTP-induced model of Parkinson's disease by suppressing glycogen synthase kinase-3 beta activity

(2016) Zhao-xiang Ren et al.   ACTA PHARMACOLOGICA SINICA

Allosteric Modulation of Sigma-1 Receptors Elicits Rapid Antidepressant Activity

(2016) Yun Wang et al.   CNS Neuroscience & Therapeutics

MicroRNA let-7c-5p protects against cerebral ischemia injury via mechanisms involving the inhibition of microglia activation

(2015) Jingshu Ni et al.   BRAIN BEHAVIOR AND IMMUNITY

MiR-124 Regulates Apoptosis and Autophagy Process in MPTP Model of Parkinson's Disease by Targeting to Bim

(2015) Huiqing Wang et al.   BRAIN PATHOLOGY

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Sigma-1 receptor deficiency reduces MPTP-induced parkinsonism and death of dopaminergic neurons

(2015) J Hong et al.   Cell Death & Disease

Neuroinflammation in Parkinson’s disease and its potential as therapeutic target

(2015) Qinqin Wang et al.   Translational Neurodegeneration

Pharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism

(2014) Veronica Francardo et al.   BRAIN

Age-dependent neuron loss is associated with impaired adult neurogenesis in forebrain neuron-specific Dicer conditional knockout mice

(2014) Shanshan Cheng et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Dicer expression is essential for adult midbrain dopaminergic neuron maintenance and survival

(2013) Xueyan Pang et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

MicroRNAs in Parkinson's disease

(2012) M. Maral Mouradian   NEUROBIOLOGY OF DISEASE

MicroRNAs in neuronal function and dysfunction

(2012) Heh-In Im et al.   TRENDS IN NEUROSCIENCES

Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

(2010) Sébastien S. Hébert et al.   HUMAN MOLECULAR GENETICS

Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus

(2008) T. H. Davis et al.   JOURNAL OF NEUROSCIENCE