Identification and classification of small molecule kinases: insights into substrate recognition and specificity

Unmasking Determinants of Specificity in the Human Kinome

(2015) Pau Creixell et al.   CELL

Mitochondrial ADCK3 Employs an Atypical Protein Kinase-like Fold to Enable Coenzyme Q Biosynthesis

(2015) Jonathan A. Stefely et al.   MOLECULAR CELL

Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway

(2015) Joana Fraga et al.   Scientific Reports

The Structure of an NDR/LATS Kinase–Mob Complex Reveals a Novel Kinase–Coactivator System and Substrate Docking Mechanism

(2015) Gergő Gógl et al.   PLOS BIOLOGY

Involvement of aph(3′)-IIa in the formation of mosaic aminoglycoside resistance genes in natural environments

(2015) Markus Woegerbauer et al.   Frontiers in Microbiology

Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity

(2014) Catherine Chen et al.   MOLECULAR CELL

Allosteric enhancement of MAP kinase p38α's activity and substrate selectivity by docking interactions

(2014) Yuji Tokunaga et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Protein folding creates structure-based, noncontiguous consensus phosphorylation motifs recognized by kinases

(2014) M. L. Duarte et al.   Science Signaling

The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192

(2014) S. Granum et al.   Science Signaling

Signal Transduction: From the Atomic Age to the Post-Genomic Era

(2014) J. Thorner et al.   Cold Spring Harbor Perspectives in Biology

Receptor Tyrosine Kinases: Legacy of the First Two Decades

(2014) J. Schlessinger   Cold Spring Harbor Perspectives in Biology

Insights into the binding specificity and catalytic mechanism ofN-acetylhexosamine 1-phosphate kinases through multiple reaction complexes

(2014) Kuei-Chen Wang et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance

(2013) Peter J. Stogios et al.   BIOCHEMICAL JOURNAL

Signalling change: signal transduction through the decades

(2013) Nancy E. Hynes et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pfam: the protein families database

(2013) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Protein structure alignment beyond spatial proximity

(2013) Sheng Wang et al.   Scientific Reports

Aminoglycoside 2′′-Phosphotransferase IIIa (APH(2′′)-IIIa) Prefers GTP over ATP

(2012) Clyde A. Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Design principles underpinning the regulatory diversity of protein kinases

(2012) K. Oruganty et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Secreted Kinase Phosphorylates Extracellular Proteins That Regulate Biomineralization

(2012) V. S. Tagliabracci et al.   SCIENCE

Discovery of cellular substrates for protein kinase A using a peptide array screening protocol

(2011) F. Donelson Smith et al.   BIOCHEMICAL JOURNAL

Interactive Tree Of Life v2: online annotation and display of phylogenetic trees made easy

(2011) I. Letunic et al.   NUCLEIC ACIDS RESEARCH

Rapid detection, classification and accurate alignment of up to a million or more related protein sequences

(2009) Andrew F. Neuwald   BIOINFORMATICS

Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases

(2009) Tara L. Davis et al.   FEBS Journal

Structure-based Mechanism of CMP-2-keto-3-deoxymanno-octulonic Acid Synthetase

(2009) Derren J. Heyes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selectivity of Docking Sites in MAPK Kinases

(2009) A. Jane Bardwell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Computational Study of the Phosphorylation Mechanism of the Insulin Receptor Tyrosine Kinase

(2009) Baojing Zhou et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Genomics, evolution, and crystal structure of a new family of bacterial spore kinases

(2009) Eric D. Scheeff et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Twice upon a time: PI3K's secret double life exposed

(2009) Emilio Hirsch et al.   TRENDS IN BIOCHEMICAL SCIENCES

Matt: Local Flexibility Aids Protein Multiple Structure Alignment

(2008) Matthew Menke et al.   PLoS Computational Biology

Multiple structural alignment by secondary structures: Algorithm and applications

(2003) Oranit Dror et al.   PROTEIN SCIENCE