Neutrophil extracellular traps drive inflammatory pathogenesis in malaria

Renal control of disease tolerance to malaria

(2019) Susana Ramos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dnase1 -deficient mice spontaneously develop a systemic lupus erythematosus-like disease

(2019) Elaine F. Kenny et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neutrophil Extracellular Traps Confine Pseudomonas aeruginosa Ocular Biofilms and Restrict Brain Invasion

(2019) Ajitha Thanabalasuriar et al.   Cell Host & Microbe

Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death

(2019) Carlos Silvestre-Roig et al.   NATURE

Antibodies to ICAM1-binding PfEMP1-DBLβ are biomarkers of protective immunity to malaria in a cohort of young children from Papua New Guinea

(2018) Sofonias K Tessema et al.   INFECTION AND IMMUNITY

The bacterial pigment pyocyanin inhibits the NLRP3 inflammasome through intracellular reactive oxygen and nitrogen species

(2018) Sebastian Virreira Winter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

(2018) Hyun Jae Lee et al.   Science Translational Medicine

Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina

(2018) Valentina Barrera et al.   eLife

Thrombin and Plasmin Alter the Proteome of Neutrophil Extracellular Traps

(2018) Chun Hwee Lim et al.   Frontiers in Immunology

Circulating Neutrophil Extracellular Traps and Neutrophil Activation Are Increased in Proportion to Disease Severity in Human Malaria

(2018) Steven Kho et al.   JOURNAL OF INFECTIOUS DISEASES

Countries must steer new response to turn the malaria tide

(2018) Tedros Adhanom Ghebreyesus et al.   LANCET

Neutrophils and Malaria

(2018) Elizabeth H. Aitken et al.   Frontiers in Immunology

Alarmins and immunity

(2017) De Yang et al.   IMMUNOLOGICAL REVIEWS

Severe malaria: what’s new on the pathogenesis front?

(2017) Samuel Crocodile Wassmer et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

ICAM-1 is a key receptor mediating cytoadherence and pathology in the Plasmodium chabaudi malaria model

(2017) Deirdre A. Cunningham et al.   MALARIA JOURNAL

Neutrophil alterations in pregnancy-associated malaria and induction of neutrophil chemotaxis by Plasmodium falciparum

(2017) S. Boström et al.   PARASITE IMMUNOLOGY

Necroptosis controls NET generation and mediates complement activation, endothelial damage, and autoimmune vasculitis

(2017) Adrian Schreiber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host DNases prevent vascular occlusion by neutrophil extracellular traps

(2017) Miguel Jiménez-Alcázar et al.   SCIENCE

Diverse stimuli engage different neutrophil extracellular trap pathways

(2017) Elaine F Kenny et al.   eLife

Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria

(2017) Jing-wen Lin et al.   Scientific Reports

Emerging roles for hemostatic dysfunction in malaria pathogenesis

(2016) J. M. OSullivan et al.   BLOOD

Alterations in Systemic Extracellular Heme and Hemopexin Are Associated With Adverse Clinical Outcomes in Ugandan Children With Severe Malaria

(2016) Robyn E. Elphinstone et al.   JOURNAL OF INFECTIOUS DISEASES

Activated Neutrophils Are Associated with Pediatric Cerebral Malaria Vasculopathy in Malawian Children

(2016) Catherine Manix Feintuch et al.   mBio

Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation

(2016) Gerben Marsman et al.   Cell Death & Disease

Targeting Neutrophils to Prevent Malaria-Associated Acute Lung Injury/Acute Respiratory Distress Syndrome in Mice

(2016) Michelle K. Sercundes et al.   PLoS Pathogens

Neutrophil Extracellular Trap Formation Is Independent of De Novo Gene Expression

(2016) Gabriel Sollberger et al.   PLoS One

Neutrophil oxidative burst activates ATM to regulate cytokine production and apoptosis

(2015) C. J. Harbort et al.   BLOOD

The role of neutrophils in the pathogenesis of systemic lupus erythematosus

(2015) Carolyne K. Smith et al.   CURRENT OPINION IN RHEUMATOLOGY

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

(2015) A. Warnatsch et al.   SCIENCE

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

(2015) Elzbieta Kolaczkowska et al.   Nature Communications

Type I Interferon Transcriptional Signature in Neutrophils and Low-Density Granulocytes Are Associated with Tissue Damage in Malaria

(2015) Bruno Coelho Rocha et al.   Cell Reports

Effects of Malaria Parasite Density on Blood Cell Parameters

(2015) Manas Kotepui et al.   PLoS One

Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease

(2014) G. Chen et al.   BLOOD

Cerebral malaria in children: using the retina to study the brain

(2014) Ian J. C. MacCormick et al.   BRAIN

Liver changes in severe Plasmodium falciparum malaria: histopathology, apoptosis and nuclear factor kappa B expression

(2014) Parnpen Viriyavejakul et al.   MALARIA JOURNAL

Alterations in cytokines and haematological parameters during the acute and convalescent phases of Plasmodium falciparum and Plasmodium vivax infections

(2014) Rodrigo Nunes Rodrigues-da-Silva et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Increased Severity and Mortality in Adults Co-Infected with Malaria and HIV in Maputo, Mozambique: A Prospective Cross-Sectional Study

(2014) Aase Berg et al.   PLoS One

In Vivo Characterization of Neutrophil Extracellular Traps in Various Organs of a Murine Sepsis Model

(2014) Koji Tanaka et al.   PLoS One

Hemozoin Induces Hepatic Inflammation in Mice and Is Differentially Associated with Liver Pathology Depending on the Plasmodium Strain

(2014) Katrien Deroost et al.   PLoS One

CD36 and malaria: friends or foes? A decade of data provides some answers

(2014) Ana Cabrera et al.   TRENDS IN PARASITOLOGY

Heme on innate immunity and inflammation

(2014) Fabianno F. Dutra et al.   Frontiers in Pharmacology

Thrombosis: tangled up in NETs

(2013) K. Martinod et al.   BLOOD

Sequestration and histopathology inPlasmodium chabaudimalaria are influenced by the immune response in an organ-specific manner

(2013) Thibaut Brugat et al.   CELLULAR MICROBIOLOGY

Neutrophil counts in persons of African origin

(2013) Christina F. Thobakgale et al.   CURRENT OPINION IN HEMATOLOGY

Malaria biology and disease pathogenesis: insights for new treatments

(2013) Louis H Miller et al.   NATURE MEDICINE

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice

(2013) K. Martinod et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Automatic quantification of in vitro NET formation

(2013) Volker Brinkmann et al.   Frontiers in Immunology

Opposition between PKC isoforms regulates histone deimination and neutrophil extracellular chromatin release

(2013) Indira Neeli et al.   Frontiers in Immunology

Plasmodium falciparum Histones Induce Endothelial Proinflammatory Response and Barrier Dysfunction

(2012) Mark R. Gillrie et al.   AMERICAN JOURNAL OF PATHOLOGY

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Respiratory Manifestations of Malaria

(2012) Walter R.J. Taylor et al.   CHEST

Cerebral malaria pathogenesis: revisiting parasite and host contributions

(2012) Georges Emile Raymond Grau et al.   Future Microbiology

Prolonged Neutrophil Dysfunction after Plasmodium falciparum Malaria Is Related to Hemolysis and Heme Oxygenase-1 Induction

(2012) A. J. Cunnington et al.   JOURNAL OF IMMUNOLOGY

Icy: an open bioimage informatics platform for extended reproducible research

(2012) Fabrice de Chaumont et al.   NATURE METHODS

A Plasma Survey Using 38 PfEMP1 Domains Reveals Frequent Recognition of the Plasmodium falciparum Antigen VAR2CSA among Young Tanzanian Children

(2012) Andrew V. Oleinikov et al.   PLoS One

Hematologic Parameters in Pediatric Uncomplicated Plasmodium falciparum Malaria in Sub-Saharan Africa

(2011) Piero Olliaro et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Host fibrinogen stably bound to hemozoin rapidly activates monocytes via TLR-4 and CD11b/CD18-integrin: a new paradigm of hemozoin action

(2011) V. Barrera et al.   BLOOD

Sickle Hemoglobin Confers Tolerance to Plasmodium Infection

(2011) Ana Ferreira et al.   CELL

Impact of Plasmodium falciparum infection on haematological parameters in children living in Western Kenya

(2011) Robert N Maina et al.   MALARIA JOURNAL

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Genome-Wide Association Study of White Blood Cell Count in 16,388 African Americans: the Continental Origins and Genetic Epidemiology Network (COGENT)

(2011) Alexander P. Reiner et al.   PLoS Genetics

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

(2010) Pingxin Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

(2010) Abdul Hakkim et al.   Nature Chemical Biology

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Upstream Open Reading Frame Controls Translation of var2csa, a Gene Implicated in Placental Malaria

(2009) Borko Amulic et al.   PLoS Pathogens

Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin

(2008) Kai Kessenbrock et al.   JOURNAL OF CLINICAL INVESTIGATION

Cytokine-associated neutrophil extracellular traps and antinuclear antibodies in Plasmodium falciparum infected children under six years of age

(2008) Virginia S Baker et al.   MALARIA JOURNAL