Aberrant activation of Notch signaling in extrahepatic cholangiocarcinoma: clinicopathological features and therapeutic potential for cancer stem cell-like properties
出版年份 2016 全文链接
标题
Aberrant activation of Notch signaling in extrahepatic cholangiocarcinoma: clinicopathological features and therapeutic potential for cancer stem cell-like properties
作者
关键词
Notch signaling, Cholangiocarcinoma, Hes-1, Cancer stem cell
出版物
BMC CANCER
Volume 16, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-11-07
DOI
10.1186/s12885-016-2919-4
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Genomic spectra of biliary tract cancer
- (2015) Hiromi Nakamura et al. NATURE GENETICS
- EGFR Blockade Enriches for Lung Cancer Stem-like Cells through Notch3-Dependent Signaling
- (2014) R. R. Arasada et al. CANCER RESEARCH
- The roles of Notch1 expression in the migration of intrahepatic cholangiocarcinoma
- (2013) Qi Zhou et al. BMC CANCER
- A Critical Role for Notch Signaling in the Formation of Cholangiocellular Carcinomas
- (2013) Steffen Zender et al. CANCER CELL
- Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer
- (2013) Shinichi Yabuuchi et al. CANCER LETTERS
- Preclinical and Clinical Studies of Gamma Secretase Inhibitors with Docetaxel on Human Breast Tumors
- (2013) A. F. Schott et al. CLINICAL CANCER RESEARCH
- Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma
- (2013) Sumera Rizvi et al. GASTROENTEROLOGY
- Notch-1 Signaling Regulates Microglia Activation via NF-κB Pathway after Hypoxic Exposure In Vivo and In Vitro
- (2013) Linli Yao et al. PLoS One
- Activation of Notch Signaling Is Required for Cholangiocarcinoma Progression and Is Enhanced by Inactivation of p53 In Vivo
- (2013) Mona El Khatib et al. PLoS One
- Constitutive Notch2 signaling induces hepatic tumors in mice
- (2012) Michael T. Dill et al. HEPATOLOGY
- Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes
- (2012) Sayaka Sekiya et al. JOURNAL OF CLINICAL INVESTIGATION
- Phase I Pharmacologic and Pharmacodynamic Study of the Gamma Secretase (Notch) Inhibitor MK-0752 in Adult Patients With Advanced Solid Tumors
- (2012) Ian Krop et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase I Study of RO4929097, a Gamma Secretase Inhibitor of Notch Signaling, in Patients With Refractory Metastatic or Locally Advanced Solid Tumors
- (2012) Anthony W. Tolcher et al. JOURNAL OF CLINICAL ONCOLOGY
- Potential utility of eGFP-expressing NOG mice (NOG-EGFP) as a high purity cancer sampling system
- (2012) Kentaro Shima et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The Gamma Secretase Inhibitor MRK-003 Attenuates Pancreatic Cancer Growth in Preclinical Models
- (2012) M. Mizuma et al. MOLECULAR CANCER THERAPEUTICS
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Risk factors for cholangiocarcinoma
- (2011) Gia L. Tyson et al. HEPATOLOGY
- Clinicopathological significance of altered Notch signaling in extrahepatic cholangiocarcinoma and gallbladder carcinoma
- (2011) Hyun Ah Yoon WORLD JOURNAL OF GASTROENTEROLOGY
- Gemcitabine alone or in combination with cisplatin in patients with biliary tract cancer: a comparative multicentre study in Japan
- (2010) T Okusaka et al. BRITISH JOURNAL OF CANCER
- Isolation and characterization of tumorigenic extrahepatic cholangiocarcinoma cells with stem cell-like properties
- (2010) Min Wang et al. INTERNATIONAL JOURNAL OF CANCER
- Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer
- (2010) Juan Valle et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion
- (2009) J Chen et al. BRITISH JOURNAL OF CANCER
- The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
- (2009) Raphael Kopan et al. CELL
- Ligand-dependent Notch Signaling Is Involved in Tumor Initiation and Tumor Maintenance in Pancreatic Cancer
- (2009) M. E. Mullendore et al. CLINICAL CANCER RESEARCH
- Major hepatectomy for perihilar cholangiocarcinoma
- (2009) Michiaki Unno et al. Journal of Hepato-Biliary-Pancreatic Sciences
- A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development
- (2009) A. Jimeno et al. MOLECULAR CANCER THERAPEUTICS
- Cancer stem cells: implications for the progression and treatment of metastatic disease
- (2008) A.K Croker et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Rational targeting of Notch signaling in cancer
- (2008) P Rizzo et al. ONCOGENE
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