标题
Destined to Die: Apoptosis and Pediatric Cancers
作者
关键词
-
出版物
Cancers
Volume 11, Issue 11, Pages 1623
出版商
MDPI AG
发表日期
2019-10-25
DOI
10.3390/cancers11111623
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The small molecule Bcl-2/Mcl-1 inhibitor TW-37 shows single-agent cytotoxicity in neuroblastoma cell lines
- (2019) Stefanie Klenke et al. BMC CANCER
- BCL-x L -selective BH3 mimetic sensitizes rhabdomyosarcoma cells to chemotherapeutics by activation of the mitochondrial pathway of apoptosis
- (2018) Sara Fatima Faqar-Uz-Zaman et al. CANCER LETTERS
- The role of XIAP in resistance to TNF-related apoptosis-inducing ligand (TRAIL) in Leukemia
- (2018) Raedeh Saraei et al. BIOMEDICINE & PHARMACOTHERAPY
- Sensitization of neuroblastoma for vincristine-induced apoptosis by Smac mimetic LCL161 is attended by G2 cell cycle arrest but is independent of NFκB, RIP1 and TNF-α
- (2017) Doerte Langemann et al. Oncotarget
- Small Molecule Survivin Inhibitor YM155 Displays Potent Activity Against Human Osteosarcoma Cells
- (2016) Shufeng Zhang et al. CANCER INVESTIGATION
- Cotreatment with Smac mimetics and demethylating agents induces both apoptotic and necroptotic cell death pathways in acute lymphoblastic leukemia cells
- (2016) Steve Gerges et al. CANCER LETTERS
- Intrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia
- (2016) M Schirmer et al. Cell Death & Disease
- XAF1 promotes neuroblastoma tumor suppression and is required for KIF1Bβ-mediated apoptosis
- (2016) Zhang'e Choo et al. Oncotarget
- Prognostic value of the Hippo pathway transcriptional coactivators YAP/TAZ and β1-integrin in conventional osteosarcoma
- (2016) Corinne Bouvier et al. Oncotarget
- Akt and Hippo Pathways in Ewing's Sarcoma Tumors and Their Prognostic Significance
- (2015) Atif A. Ahmed et al. Journal of Cancer
- Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma
- (2015) Katherine K. Slemmons et al. PLoS One
- XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells
- (2015) Daniel Moreno-Martínez et al. Oncotarget
- Childhood and adolescent cancer statistics, 2014
- (2014) Elizabeth Ward et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Embelin Sensitizes Acute Myeloid Leukemia Cells to TRAIL through XIAP Inhibition and NF-κB Inactivation
- (2014) Tianxin Yang et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 against Pediatric Acute Lymphoblastic Leukemia Xenografts
- (2014) S. Suryani et al. CLINICAL CANCER RESEARCH
- TNF and TNF-receptors: From mediators of cell death and inflammation to therapeutic giants – past, present and future
- (2014) Lisa M. Sedger et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Expression and prognostic significance of livin/BIRC7 in childhood acute lymphoblastic leukemia
- (2014) Lamia Ibrahim et al. MEDICAL ONCOLOGY
- RNA Helicase A Is a Downstream Mediator of KIF1B Tumor-Suppressor Function in Neuroblastoma
- (2014) Z. X. Chen et al. Cancer Discovery
- Death receptors as targets in cancer
- (2013) O Micheau et al. BRITISH JOURNAL OF PHARMACOLOGY
- Pan-Mammalian Target of Rapamycin (mTOR) Inhibitor AZD8055 Primes Rhabdomyosarcoma Cells for ABT-737-induced Apoptosis by Down-regulating Mcl-1 Protein
- (2013) Ellen Preuss et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- BIRC5(survivin) splice variant expression correlates with refractory disease and poor outcome in pediatric acute myeloid leukemia: A report from the Children's Oncology Group
- (2013) Andrew S. Moore et al. PEDIATRIC BLOOD & CANCER
- Involvement of substance P and the NK-1 receptor in cancer progression
- (2013) Miguel Muñoz et al. PEPTIDES
- Mechanisms of Action of Bcl-2 Family Proteins
- (2013) A. Shamas-Din et al. Cold Spring Harbor Perspectives in Biology
- The Bcl-2/Bax and Ras/Raf/MEK/ERK signaling pathways: implications in pediatric leukemia pathogenesis and new prospects for therapeutic approaches
- (2013) Orsola Vitagliano et al. Expert Review of Hematology
- Mitochondrial Bcl-2 Family Dynamics Define Therapy Response and Resistance in Neuroblastoma
- (2012) K. C. Goldsmith et al. CANCER RESEARCH
- Smac Mimetic LBW242 Sensitizes XIAP-Overexpressing Neuroblastoma Cells for TNF- -Independent Apoptosis
- (2012) G. Eschenburg et al. CANCER RESEARCH
- Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies
- (2012) Haibo Bai et al. HUMAN PATHOLOGY
- Phase I Trial and Pharmacokinetic Study of Lexatumumab in Pediatric Patients With Solid Tumors
- (2012) Melinda S. Merchant et al. JOURNAL OF CLINICAL ONCOLOGY
- Functional polymorphisms inFAS, FASLandCASP8 genes and risk of childhood acute lymphoblastic leukemia: a case–control study
- (2012) Na Tong et al. LEUKEMIA & LYMPHOMA
- Targeting IAP proteins for therapeutic intervention in cancer
- (2012) Simone Fulda et al. NATURE REVIEWS DRUG DISCOVERY
- BIRC5 expression is a poor prognostic marker in Ewing sarcoma
- (2012) Pooja Hingorani et al. PEDIATRIC BLOOD & CANCER
- Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells
- (2011) Aiguo Liu et al. CANCER SCIENCE
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Synergistic Activity of Fenretinide and the Bcl-2 Family Protein Inhibitor ABT-737 against Human Neuroblastoma
- (2011) H. Fang et al. CLINICAL CANCER RESEARCH
- BIRC6/Apollon gene expression in childhood acute leukemia: impact on therapeutic response and prognosis
- (2011) Eman Abdel Rahman Ismail et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Apoptosis in cancer: from pathogenesis to treatment
- (2011) Rebecca SY Wong JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis
- (2011) S Löder et al. LEUKEMIA
- Down-regulation of XIAP by AEG35156 in paediatric tumour cells induces apoptosis and sensitises cells to cytotoxic agents
- (2011) Makin ONCOLOGY REPORTS
- Initial testing (stage 1) of LCL161, a SMAC mimetic, by the pediatric preclinical testing program
- (2011) Peter J. Houghton et al. PEDIATRIC BLOOD & CANCER
- Hedgehog pathway activity in pediatric embryonal rhabdomyosarcoma and undifferentiated sarcoma: A report from the Children's Oncology Group
- (2011) Joseph G. Pressey et al. PEDIATRIC BLOOD & CANCER
- Sensitization of Osteosarcoma Cell Line SaOS-2 to Chemotherapy by Downregulating Survivin
- (2010) Jun Zou et al. ARCHIVES OF MEDICAL RESEARCH
- Hedgehog beyond medulloblastoma and basal cell carcinoma
- (2010) Stephan Teglund et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists
- (2010) Brian J. Lestini et al. CANCER BIOLOGY & THERAPY
- Increased expression of the hedgehog signaling pathway in pediatric solid malignancies
- (2010) Takaharu Oue et al. JOURNAL OF PEDIATRIC SURGERY
- Influence of high expression of Smac/DIABLO protein on the clinical outcome in acute myeloid leukemia patients
- (2010) Agnieszka Pluta et al. LEUKEMIA RESEARCH
- Mitochondria and cell death: outer membrane permeabilization and beyond
- (2010) Stephen W. G. Tait et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2 proteins and enhanced mitochondrial apoptosis
- (2010) A Bender et al. ONCOGENE
- microRNA-143, down-regulated in osteosarcoma, promotes apoptosis and suppresses tumorigenicity by targeting Bcl-2
- (2010) Ji ONCOLOGY REPORTS
- XIAP expression is post-transcriptionally upregulated in childhood ALL and is associated with glucocorticoid response in T-cell ALL
- (2010) Patrick Hundsdoerfer et al. PEDIATRIC BLOOD & CANCER
- Smac mimetics as new cancer therapeutics
- (2009) Derrick J. Chen et al. ANTI-CANCER DRUGS
- BH3 response profiles from neuroblastoma mitochondria predict activity of small molecule Bcl-2 family antagonists
- (2009) K C Goldsmith et al. CELL DEATH AND DIFFERENTIATION
- The Many Roles of FAS Receptor Signaling in the Immune System
- (2009) Andreas Strasser et al. IMMUNITY
- Following TRAIL’s path in the immune system
- (2009) Christina Falschlehner et al. IMMUNOLOGY
- Small molecule XIAP inhibitors sensitize childhood acute leukemia cells for CD95-induced apoptosis
- (2009) Sandra Loeder et al. INTERNATIONAL JOURNAL OF CANCER
- Survivin minigene DNA vaccination is effective against neuroblastoma
- (2009) Stefan Fest et al. INTERNATIONAL JOURNAL OF CANCER
- Neuronal apoptosis by prolyl hydroxylation: implication in nervous system tumours and the Warburg conundrum
- (2009) Susanne Schlisio JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Phase I/II Trial of AEG35156 X-Linked Inhibitor of Apoptosis Protein Antisense Oligonucleotide Combined With Idarubicin and Cytarabine in Patients With Relapsed or Primary Refractory Acute Myeloid Leukemia
- (2009) Aaron D. Schimmer et al. JOURNAL OF CLINICAL ONCOLOGY
- Overexpression of X-linked Inhibitor of Apoptosis Protein (XIAP) is an Independent Unfavorable Prognostic Factor in Childhood de Novo Acute Myeloid Leukemia
- (2009) Ki Woong Sung et al. JOURNAL OF KOREAN MEDICAL SCIENCE
- The Bcl-2 Homology Domain 3 Mimetic ABT-737 Targets the Apoptotic Machinery in Acute Lymphoblastic Leukemia Resulting in Synergistic in Vitro and in Vivo Interactions with Established Drugs
- (2009) L. M. High et al. MOLECULAR PHARMACOLOGY
- Initial testing (stage 1) of mapatumumab (HGS-ETR1) by the pediatric preclinical testing program
- (2009) Malcolm A. Smith et al. PEDIATRIC BLOOD & CANCER
- Inhibitor of apoptosis proteins and apoptosis
- (2008) Yunbo Wei et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Notch Signaling in Leukemia
- (2008) Jon C. Aster et al. Annual Review of Pathology-Mechanisms of Disease
- Bcl-2 family members as molecular targets in cancer therapy
- (2008) Isabel Marzo et al. BIOCHEMICAL PHARMACOLOGY
- Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance
- (2008) M. Fakler et al. BLOOD
- ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor
- (2008) C. Tse et al. CANCER RESEARCH
- The mitochondrial serine protease HtrA2/Omi: an overview
- (2008) L Vande Walle et al. CELL DEATH AND DIFFERENTIATION
- Critical Role of Notch Signaling in Osteosarcoma Invasion and Metastasis
- (2008) P. Zhang et al. CLINICAL CANCER RESEARCH
- Blocking the hedgehog pathway inhibits hepatoblastoma growth
- (2008) Melanie Eichenmüller et al. HEPATOLOGY
- To kill a tumor cell: the potential of proapoptotic receptor agonists
- (2008) Avi Ashkenazi et al. JOURNAL OF CLINICAL INVESTIGATION
- Medulloblastoma Stem Cells
- (2008) Xing Fan et al. JOURNAL OF CLINICAL ONCOLOGY
- Mechanism of Synergy of N-(4-Hydroxyphenyl)Retinamide and ABT-737 in Acute Lymphoblastic Leukemia Cell Lines: Mcl-1 Inactivation
- (2008) Min H. Kang et al. JNCI-Journal of the National Cancer Institute
- Notch signaling in pediatric malignancies
- (2008) Patrick A. Zweidler-McKay Current Oncology Reports
- Initial testing (stage 1) of the BH3 mimetic ABT-263 by the pediatric preclinical testing program
- (2007) Richard Lock et al. PEDIATRIC BLOOD & CANCER
- Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways
- (2003) Sai Latha Shankar et al. JOURNAL OF NEUROCHEMISTRY
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