Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL

Effects of Cerebral Blood Flow and White Matter Integrity on Cognition in CADASIL Patients

(2019) Xinzhen Yin et al.   Frontiers in Psychiatry

BOLD-based cerebrovascular reactivity vascular transfer function isolates amplitude and timing responses to better characterize cerebral small vessel disease

(2019) Sarah Atwi et al.   NMR IN BIOMEDICINE

Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

(2019) Angeliki M. Nikolakopoulou et al.   NATURE NEUROSCIENCE

Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI

(2019) Shir Filo et al.   Nature Communications

Severe White Matter Astrocytopathy in CADASIL

(2018) Yoshiki Hase et al.   BRAIN PATHOLOGY

Severity of arterial defects in the retina correlates with the burden of intracerebral haemorrhage in COL4A1-related stroke

(2018) Julien Ratelade et al.   JOURNAL OF PATHOLOGY

Pericyte degeneration causes white matter dysfunction in the mouse central nervous system

(2018) Axel Montagne et al.   NATURE MEDICINE

Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats

(2018) Rikesh M. Rajani et al.   Science Translational Medicine

Different Types of White Matter Hyperintensities in CADASIL

(2018) Edouard Duchesnay et al.   Frontiers in Neurology

Different types of white matter hyperintensities in CADASIL: Insights from 7-Tesla MRI

(2017) François De Guio et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Detection, risk factors, and functional consequences of cerebral microinfarcts

(2017) Susanne J van Veluw et al.   LANCET NEUROLOGY

Cause and prevention of demyelination in a model multiple sclerosis lesion

(2016) Roshni A. Desai et al.   ANNALS OF NEUROLOGY

Reducing Timp3 or vitronectin ameliorates disease manifestations in CADASIL mice

(2016) Carmen Capone et al.   ANNALS OF NEUROLOGY

Stroke injury, cognitive impairment and vascular dementia

(2016) Raj N. Kalaria et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Pericytes are involved in the pathogenesis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

(2015) Mitrajit Ghosh et al.   ANNALS OF NEUROLOGY

APOE ɛ2 is associated with white matter hyperintensity volume in CADASIL

(2015) Benno Gesierich et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

HANAC Syndrome Col4a1 Mutation Causes Neonate Glomerular Hyperpermeability and Adult Glomerulocystic Kidney Disease

(2015) Z. Chen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Immunolocalization of platelet-derived growth factor receptor-β (PDGFR-β) and pericytes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)

(2015) Lucinda J.L. Craggs et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

White Matter Changes in Dementia: Role of Impaired Drainage of Interstitial Fluid

(2014) Roy O. Weller et al.   BRAIN PATHOLOGY

Microvascular Pathology and Morphometrics of Sporadic and Hereditary Small Vessel Diseases of the Brain

(2014) Lucinda J.L. Craggs et al.   BRAIN PATHOLOGY

CADASIL and CARASIL

(2014) Saara Tikka et al.   BRAIN PATHOLOGY

Ablation of matrix metalloproteinase-9 gene decreases cerebrovascular permeability and fibrinogen deposition post traumatic brain injury in mice

(2014) Nino Muradashvili et al.   METABOLIC BRAIN DISEASE

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Abnormal recruitment of extracellular matrix proteins by excess Notch3ECD: a new pathomechanism in CADASIL

(2013) Marie Monet-Leprêtre et al.   BRAIN

Brain Microvascular Accumulation and Distribution of the NOTCH3 Ectodomain and Granular Osmiophilic Material in CADASIL

(2013) Yumi Yamamoto et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

White matter pathology and disconnection in the frontal lobe in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)

(2013) Lucinda J. L. Craggs et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Heterogeneity in age-related white matter changes

(2011) Reinhold Schmidt et al.   ACTA NEUROPATHOLOGICA

Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer’s disease, and dementia with Lewy bodies

(2010) Masafumi Ihara et al.   ACTA NEUROPATHOLOGICA

Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease

(2010) Anne Joutel et al.   JOURNAL OF CLINICAL INVESTIGATION

Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges

(2010) Leonardo Pantoni   LANCET NEUROLOGY

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

CADASIL

(2009) Hugues Chabriat et al.   LANCET NEUROLOGY

Neuropathological Correlates of Temporal Pole White Matter Hyperintensities in CADASIL

(2009) Yumi Yamamoto et al.   STROKE

Donepezil in patients with subcortical vascular cognitive impairment: a randomised double-blind trial in CADASIL

(2008) Martin Dichgans et al.   LANCET NEUROLOGY

Impact of MRI markers in subcortical vascular dementia: A multi-modal analysis in CADASIL

(2008) Anand Viswanathan et al.   NEUROBIOLOGY OF AGING

Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis

(2007) Andrew J. Farrall et al.   NEUROBIOLOGY OF AGING