Sudden death due to paralysis and synaptic and behavioral deficits when Hip14/Zdhhc17 is deleted in adult mice

Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers

(2015) Shaun S. Sanders et al.   PLoS Computational Biology

The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease

(2014) Stefanie L. Butland et al.   HUMAN MOLECULAR GENETICS

Striatal Synaptic Dysfunction and Hippocampal Plasticity Deficits in the Hu97/18 Mouse Model of Huntington Disease

(2014) Karolina Kolodziejczyk et al.   PLoS One

Tracking Brain Palmitoylation Change: Predominance of Glial Change in a Mouse Model of Huntington’s Disease

(2013) Junmei Wan et al.   CHEMISTRY & BIOLOGY

Bidirectional Control of Postsynaptic Density-95 (PSD-95) Clustering by Huntingtin

(2013) Matthew P. Parsons et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Local palmitoylation cycles define activity-regulated postsynaptic subdomains

(2013) Yuko Fukata et al.   JOURNAL OF CELL BIOLOGY

Dysregulated Striatal Neuronal Processing and Impaired Motor Behavior in Mice Lacking Huntingtin Interacting Protein 14 (HIP14)

(2013) Ana María Estrada-Sánchez et al.   PLoS One

Memory and synaptic deficits in Hip14/DHHC17 knockout mice

(2013) A. J. Milnerwood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A fully humanized transgenic mouse model of Huntington disease

(2012) Amber L. Southwell et al.   HUMAN MOLECULAR GENETICS

Low Levels of Human HIP14 Are Sufficient to Rescue Neuropathological, Behavioural, and Enzymatic Defects Due to Loss of Murine HIP14 in Hip14−/− Mice

(2012) Fiona B. Young et al.   PLoS One

Tamoxifen Induces Rapid, Reversible Atrophy, and Metaplasia in Mouse Stomach

(2011) Won Jae Huh et al.   GASTROENTEROLOGY

Altered palmitoylation and neuropathological deficits in mice lacking HIP14

(2011) R. R. Singaraja et al.   HUMAN MOLECULAR GENETICS

Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14

(2011) Kun Huang et al.   HUMAN MOLECULAR GENETICS

Palmitoyl Acyltransferase zD17 Mediates Neuronal Responses in Acute Ischemic Brain Injury by Regulating JNK Activation in a Signaling Module

(2011) G. Yang et al.   JOURNAL OF NEUROSCIENCE

Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease

(2011) Jeffrey B. Carroll et al.   NEUROBIOLOGY OF DISEASE

Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function

(2011) L.A. Raymond et al.   NEUROSCIENCE

Putting proteins in their place: Palmitoylation in Huntington disease and other neuropsychiatric diseases

(2011) Fiona B. Young et al.   PROGRESS IN NEUROBIOLOGY

A human MAP kinase interactome

(2010) Sourav Bandyopadhyay et al.   NATURE METHODS

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

(2010) Austen J. Milnerwood et al.   NEURON

Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease

(2010) Austen J. Milnerwood et al.   TRENDS IN NEUROSCIENCES

Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin

(2009) M. A. Pouladi et al.   BRAIN

Intrabody Gene Therapy Ameliorates Motor, Cognitive, and Neuropathological Symptoms in Multiple Mouse Models of Huntington's Disease

(2009) A. L. Southwell et al.   JOURNAL OF NEUROSCIENCE

Dual Palmitoylation of NR2 Subunits Regulates NMDA Receptor Trafficking

(2009) Takashi Hayashi et al.   NEURON

Huntingtin-interacting Proteins, HIP14 and HIP14L, Mediate Dual Functions, Palmitoyl Acyltransferase and Mg2+Transport

(2008) Angela Goytain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

(2008) M.A. Hickey et al.   NEUROSCIENCE