Therapeutic Anabolic and Anticatabolic Benefits of Natural Chinese Medicines for the Treatment of Osteoporosis

Curculigoside exerts significant anti‑arthritic effects in�vivo and in�vitro via regulation of the JAK/STAT/NF‑κB signaling pathway

(2019) Shirui Tan et al.   Molecular Medicine Reports

Osthole alleviates MPTP-induced Parkinson’s disease mice by suppressing Notch signaling pathway

(2019) Yu Wang et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

mTORC1 Activation in Osteoclasts Prevents Bone Loss in a Mouse Model of Osteoporosis

(2019) Manami Hiraiwa et al.   Frontiers in Pharmacology

Tanshinone IIA Exerts Anti-Inflammatory and Immune-Regulating Effects on Vulnerable Atherosclerotic Plaque Partially via the TLR4/MyD88/NF-κB Signal Pathway

(2019) Zhuo Chen et al.   Frontiers in Pharmacology

Integrated pathological cell fishing and network pharmacology approach to investigate main active components of Er-Xian decotion for treating osteoporosis

(2019) Nani Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Du-Zhong (Eucommia ulmoides Oliv.) Cortex Extract Alleviates Lead Acetate-Induced Bone Loss in Rats

(2018) Shanshan Qi et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

The ethanol extraction of prepared Psoralea corylifolia induces apoptosis and autophagy and alteres genes expression assayed by cDNA microarray in human prostate cancer PC-3 cells

(2018) Chia-Hsin Lin et al.   ENVIRONMENTAL TOXICOLOGY

Antioxidative and anti-proliferative potential of Curculigo orchioides Gaertn in oxidative stress induced cytotoxicity: In vitro , ex vivo and in silico studies

(2018) Iram Iqbal Hejazi et al.   FOOD AND CHEMICAL TOXICOLOGY

Glucocorticoids inhibit notch target gene expression in osteoblasts

(2018) Stefano Zanotti et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cistanche deserticola polysaccharide attenuates osteoclastogenesis and bone resorption via inhibiting RANKL signaling and reactive oxygen species production

(2018) Dezhi Song et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cistanches Herba: An overview of its chemistry, pharmacology, and pharmacokinetics property

(2018) Zhifei Fu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Puerarin inhibits TRPM3/miR-204 to promote MC3T3-E1 cells proliferation, differentiation and mineralization

(2018) Xiangwei Zeng et al.   PHYTOTHERAPY RESEARCH

Eucommia ulmoides Ameliorates Glucotoxicity by Suppressing Advanced Glycation End-Products in Diabetic Mice Kidney

(2018) Moon Do et al.   Nutrients

Structural elucidation and anti-osteoporosis activities of polysaccharides obtained from Curculigo orchioides

(2018) Xueqian Wang et al.   CARBOHYDRATE POLYMERS

Psoralen and Bakuchiol Ameliorate M-CSF Plus RANKL-Induced Osteoclast Differentiation and Bone Resorption Via Inhibition of AKT and AP-1 Pathways in Vitro

(2018) Lijuan Chai et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Investigation of inulins from the roots of Morinda officinalis for potential therapeutic application as anti-osteoporosis agent

(2018) Keming Jiang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Simultaneous Determination of Ten Bioactive Components in Raw and Processed Radix Dipsaci by UPLC-Q-TOF-MS

(2018) Yi Tao et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Rubiadin-1-methyl ether from Morinda officinalis How. Inhibits osteoclastogenesis through blocking RANKL-induced NF-κB pathway

(2018) Yu-Qiong He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Efficacy of Chinese herb Cistanche Yishen granules in treatment of tinnitus for patients with chronic nephritis

(2018) Xiaoli Fan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Radix Salviae miltiorrhizae improves bone microstructure and strength through Wnt/β-catenin and osteoprotegerin/receptor activator for nuclear factor-κB ligand/cathepsin K signaling in ovariectomized rats

(2018) Haixia Liu et al.   PHYTOTHERAPY RESEARCH

Bergapten suppresses RANKL-induced osteoclastogenesis and ovariectomy-induced osteoporosis via suppression of NF-κB and JNK signaling pathways

(2018) Guiping Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metabolites of curculigoside in rats and their antiosteoporotic activities in osteoblastic MC3T3-E1 cells

(2017) Liang Wang et al.   FITOTERAPIA

Bajijiasu Abrogates Osteoclast Differentiation via the Suppression of RANKL Signaling Pathways through NF-κB and NFAT

(2017) Guoju Hong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Icariin ameliorates dexamethasone‑induced bone deterioration in an experimental mouse model via activation of microRNA‑186 inhibition of cathepsin K

(2017) Yongsheng Ma et al.   Molecular Medicine Reports

Therapeutic Effect of Cistanoside A on Bone Metabolism of Ovariectomized Mice

(2017) Xiaoxue Xu et al.   MOLECULES

The effect of icariin on bone metabolism and its potential clinical application

(2017) Z. Wang et al.   OSTEOPOROSIS INTERNATIONAL

Oral administration of kaempferol inhibits bone loss in rat model of ovariectomy-induced osteopenia

(2017) Beata Nowak et al.   Pharmacological Reports

A Chinese patent medicine Salvia miltiorrhiza depside salts for infusion combined with conventional treatment for patients with angina pectoris: A systematic review and meta-analysis of randomized controlled trials

(2017) Yili Zhang et al.   PHYTOMEDICINE

Cnidium officinale Makino extract induces apoptosis through activation of caspase-3 and p53 in human liver cancer HepG2 cells

(2017) Heeok Hong et al.   Experimental and Therapeutic Medicine

Icariin improves osteoporosis, inhibits the expression of PPARγ, C/EBPα, FABP4 mRNA, N1ICD and jagged1 proteins, and increases Notch2 mRNA in ovariectomized rats

(2017) Hengrui Liu et al.   Experimental and Therapeutic Medicine

Osthole Enhances Osteogenesis in Osteoblasts by Elevating Transcription Factor Osterix via cAMP/CREB Signaling In Vitro and In Vivo

(2017) Zhong-Rong Zhang et al.   Nutrients

Prebiotic Effect of Fructooligosaccharides from Morinda officinalis on Alzheimer’s Disease in Rodent Models by Targeting the Microbiota-Gut-Brain Axis

(2017) Diling Chen et al.   Frontiers in Aging Neuroscience

Salvia miltiorrhizaRoots against Cardiovascular Disease: Consideration of Herb-Drug Interactions

(2017) Feng Chen et al.   Biomed Research International

Pharmacological Therapy of Osteoporosis: A Systematic Current Review of Literature

(2017) Vito Pavone et al.   Frontiers in Pharmacology

New insights into the tonifying kidney-yin herbs and formulas for the treatment of osteoporosis

(2017) Jian-Bo He et al.   Archives of Osteoporosis

Isobavachalcone Attenuates MPTP-Induced Parkinson's Disease in Mice by Inhibition of Microglial Activation through NF-κB Pathway

(2017) Haoran Jing et al.   PLoS One

The Chemical Constituents and Bioactivities of Psoralea corylifolia Linn.: A Review

(2016) Xuenong Zhang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Epidemiology of fractures in the United Kingdom 1988–2012: Variation with age, sex, geography, ethnicity and socioeconomic status

(2016) Elizabeth M. Curtis et al.   BONE

Implications of the Interaction Between miRNAs and Autophagy in Osteoporosis

(2016) Gengyang Shen et al.   CALCIFIED TISSUE INTERNATIONAL

Drospirenone plus estradiol and the risk of serious cardiovascular events in postmenopausal women

(2016) J. Dinger et al.   CLIMACTERIC

Impact of estrogen type on cardiovascular safety of combined oral contraceptives

(2016) Jürgen Dinger et al.   CONTRACEPTION

Health-Promoting Properties ofEucommia ulmoides: A Review

(2016) Tarique Hussain et al.   Evidence-based Complementary and Alternative Medicine

Comparison of the Effect of Velvet Antler from Different Sections on Longitudinal Bone Growth of Adolescent Rats

(2016) Hye Kyung Kim et al.   Evidence-based Complementary and Alternative Medicine

Monotropein isolated from the roots of Morinda officinalis increases osteoblastic bone formation and prevents bone loss in ovariectomized mice

(2016) Zhiguo Zhang et al.   FITOTERAPIA

Puerariamirificaalleviates cortical bone loss in naturally menopausal monkeys

(2016) Donlaporn Kittivanichkul et al.   JOURNAL OF ENDOCRINOLOGY

Echinacoside and Cistanche tubulosa (Schenk) R. wight ameliorate bisphenol A-induced testicular and sperm damage in rats through gonad axis regulated steroidogenic enzymes

(2016) Zhihui Jiang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-osteoporosis effect of Epimedium via an estrogen-like mechanism based on a system-level approach

(2016) Feifei Xu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Extract from Eucommia ulmoides Oliv. ameliorates arthritis via regulation of inflammation, synoviocyte proliferation and osteoclastogenesis in vitro and in vivo

(2016) Jian-Ying Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of salvianolate on bone metabolism in glucocorticoid-treated lupus-prone B6.MRL-Faslpr/J mice

(2016) Yanzhi Liu et al.   Drug Design Development and Therapy

Icariside II activates EGFR-Akt-Nrf2 signaling and protects osteoblasts from dexamethasone

(2016) Weidong Liu et al.   Oncotarget

Tanshinol stimulates bone formation and attenuates dexamethasone-induced inhibition of osteogenesis in larval zebrafish

(2016) Shiying Luo et al.   Journal of Orthopaedic Translation

Cnidium monnieri: A Review of Traditional Uses, Phytochemical and Ethnopharmacological Properties

(2015) Yi-Min Li et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Icariin protects against titanium particle-induced osteolysis and inflammatory response in a mouse calvarial model

(2015) Hongguo Shao et al.   BIOMATERIALS

LC/MS/MS determination and pharmacokinetic study of iridoid glycosides monotropein and deacetylasperulosidic acid isomers in rat plasma after oral administration ofMorinda officinalisextract

(2015) Chunmin Li et al.   BIOMEDICAL CHROMATOGRAPHY

Icariin induces osteogenic differentiation of bone mesenchymal stem cells in a MAPK-dependent manner

(2015) Yuqiong Wu et al.   CELL PROLIFERATION

Shen (Kidney)-tonifying principle for primary osteoporosis: to treat both the disease and the Chinese medicine syndrome

(2015) Bing Shu et al.   Chinese Journal of Integrative Medicine

Herba Epimedii: An Ancient Chinese Herbal Medicine in the Prevention and Treatment of Osteoporosis

(2015) Lili Wang et al.   CURRENT PHARMACEUTICAL DESIGN

Corrigendum to ‘Eucommia ulmoides Oliv. bark aqueous extract inhibits osteoarthritis in a rat model of osteoarthritis’

(2015) Guo-ping Xie et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effect of bajijiasu isolated from Morinda officinalis F. C. how on sexual function in male mice and its antioxidant protection of human sperm

(2015) Ze-Qing Wu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Osteoporosis: the evolution of a diagnosis

(2015) M. Lorentzon et al.   JOURNAL OF INTERNAL MEDICINE

Positive skeletal effect of two ingredients of Psoralea corylifolia L. on estrogen deficiency-induced osteoporosis and the possible mechanisms of action

(2015) Ze-Bin Weng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Radix Dipsaci total saponins stimulate MC3T3-E1 cell differentiation via the bone morphogenetic protein-2/MAPK/Smad-dependent Runx2 pathway

(2015) YIN-BO NIU et al.   Molecular Medicine Reports

Puerarin enhances proliferation and osteoblastic differentiation of human bone marrow stromal cells via a nitric oxide/cyclic guanosine monophosphate signaling pathway

(2015) HAIHONG LV et al.   Molecular Medicine Reports

Anti-osteoporotic activity of puerarin 6″-O-xyloside on ovariectomized mice and its potential mechanism

(2015) Hai Li et al.   PHARMACEUTICAL BIOLOGY

Effect of serum from postmenopausal women with osteoporosis exhibiting the Kidney-Yang deficiency pattern on bone formation in an hFOB 1.19 human osteoblastic cell line

(2015) YACHAN LI et al.   Experimental and Therapeutic Medicine

Salvianolic acid B promotes bone formation by increasing activity of alkaline phosphatase in a rat tibia fracture model: a pilot study

(2015) Xufeng He et al.   BMC Complementary and Alternative Medicine

Icariin recovers the osteogenic differentiation and bone formation of bone marrow stromal cells from a rat model of estrogen deficiency-induced osteoporosis

(2015) ZHIQIANG LUO et al.   Molecular Medicine Reports

Du-Zhong (Eucommia ulmoides) Prevents Disuse-Induced Osteoporosis in Hind Limb Suspension Rats

(2014) Yalei Pan et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Phytoandrogenic properties ofEurycoma longifoliaas natural alternative to testosterone replacement therapy

(2014) A. George et al.   ANDROLOGIA

Salvia miltiorrhiza: An ancient Chinese herbal medicine as a source for anti-osteoporotic drugs

(2014) Yubo Guo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of total lignans from Eucommia ulmoides barks prevent bone loss in vivo and in vitro

(2014) Rong Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cuscuta chinensis Lam.: A systematic review on ethnopharmacology, phytochemistry and pharmacology of an important traditional herbal medicine

(2014) Sineeporn Donnapee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Confocal mirco-Raman spectroscopic analysis of the antioxidant protection mechanism of the oligosaccharides extracted from Morinda officinalis on human sperm DNA

(2014) Di-Ling Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Inhibitory effect of icariin on Ti-induced inflammatory osteoclastogenesis

(2014) Jingfu Cui et al.   JOURNAL OF SURGICAL RESEARCH

Treatment of Radix Dipsaci extract prevents long bone loss induced by modeled microgravity in hindlimb unloading rats

(2014) Yinbo Niu et al.   PHARMACEUTICAL BIOLOGY

Chinese herbal medicine for bone health

(2014) Emmanuel Mukwaya et al.   PHARMACEUTICAL BIOLOGY

Synergistic inhibitory effect of Icariside II with Icaritin from Herba Epimedii on pre-osteoclastic RAW264.7 cell growth

(2014) Yan-Qiu Liu et al.   PHYTOMEDICINE

Puerarin concurrently stimulates osteoprotegerin and inhibits receptor activator of NF-κB ligand (RANKL) and interleukin-6 production in human osteoblastic MG-63 cells

(2014) Yue Wang et al.   PHYTOMEDICINE

Effects ofEucommia ulmoidesExtract on Longitudinal Bone Growth Rate in Adolescent Female Rats

(2014) Ji Young Kim et al.   PHYTOTHERAPY RESEARCH

Mechanisms of “kidney governing bones” theory in traditional Chinese medicine

(2014) Dahong Ju et al.   Frontiers of Medicine

Icariin Protects Against Glucocorticoid-Induced Osteoporosis In Vitro and Prevents Glucocorticoid-Induced Osteocyte Apoptosis In Vivo

(2013) Rongjie Feng et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Icariin induces osteoblast proliferation, differentiation and mineralization through estrogen receptor-mediated ERK and JNK signal activation

(2013) Lige Song et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Icariin Augments Bone Formation and Reverses the Phenotypes of Osteoprotegerin-Deficient Mice through the Activation of Wnt/β-Catenin-BMP Signaling

(2013) Xiao-Feng Li et al.   Evidence-based Complementary and Alternative Medicine

Antiresorptive Activity ofBacillus-Fermented Antler Extracts: Inhibition of Osteoclast Differentiation

(2013) Sik-Won Choi et al.   Evidence-based Complementary and Alternative Medicine

Phenolic glycosides from Curculigo orchioides Gaertn.

(2013) Zhen-Hui Wang et al.   FITOTERAPIA

Medicinal plants of genus Curculigo: Traditional uses and a phytochemical and ethnopharmacological review

(2013) Yan Nie et al.   JOURNAL OF ETHNOPHARMACOLOGY

The anti-osteoporotic effect of velvet antler polypeptides from Cervus elaphus Linnaeus in ovariectomized rats

(2013) Lian-Zhu Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cuscuta chinensis seeds water extraction protecting murine osteoblastic MC3T3-E1 cells against tertiary butyl hydroperoxide induced injury

(2013) Jian-mei Gao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effect of the RW-Cb and its active ingredient like P-acid and P-aldehyde on primary rat osteoblasts

(2013) Gang Xu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Comparison of chemical compositions and osteoprotective effects of different sections of velvet antler

(2013) Sung-Hui Tseng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Bioactive components of velvet antlers and their pharmacological properties

(2013) Zhigang Sui et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Curculigoside promotes osteogenic differentiation of bone marrow stromal cells from ovariectomized rats

(2013) Qingping Shen et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Puerarin stimulates proliferation and differentiation and protects against cell death in human osteoblastic MG-63 cells via ER-dependent MEK/ERK and PI3K/Akt activation

(2013) Yue Wang et al.   PHYTOMEDICINE

Antiosteoporotic activity of echinacoside in ovariectomized rats

(2013) Fei Li et al.   PHYTOMEDICINE

Osteoblasts proliferation and differentiation stimulating activities of the main components of Fructus Psoraleae corylifoliae

(2013) Wei D. Li et al.   PHYTOMEDICINE

Icariin Induces Osteoblast Differentiation and Mineralization without Dexamethasone in Vitro

(2013) Xiao-Ni Ma et al.   PLANTA MEDICA

Curculigoside Improves Osteogenesis of Human Amniotic Fluid-Derived Stem Cells

(2013) Meimei Liu et al.   STEM CELLS AND DEVELOPMENT

Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway

(2013) Ling-juan Liu et al.   International Journal of Endocrinology

Curculigoside isolated from Curculigo orchioides prevents hydrogen peroxide-induced dysfunction and oxidative damage in calvarial osteoblasts

(2012) Y. Wang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Eucommia Leaf Extract (ELE) Prevents OVX-Induced Osteoporosis and Obesity in Rats

(2012) Wenping Zhang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Therapeutic effects of radix dipsaci, pyrola herb, and cynomorium songaricum on bone metabolism of ovariectomized rats

(2012) Meijie Liu et al.   BMC Complementary and Alternative Medicine

Echinacoside promotes bone regeneration by increasing OPG/RANKL ratio in MC3T3-E1 cells

(2012) Fei Li et al.   FITOTERAPIA

Icariin promotes bone formation via the BMP-2/Smad4 signal transduction pathway in the hFOB 1.19 human osteoblastic cell line

(2012) WENNA LIANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Puerarin stimulates osteoblasts differentiation and bone formation through estrogen receptor, p38 MAPK, and Wnt/β-catenin pathways

(2012) Pan-Pan Wang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19)

(2012) Lijuan Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Deer antler base as a traditional Chinese medicine: A review of its traditional uses, chemistry and pharmacology

(2012) Feifei Wu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cistanche deserticolaextract increases bone formation in osteoblasts

(2012) Te-Mao Li et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The osteoprotective effect of psoralen in ovariectomy-induced osteoporotic rats via stimulating the osteoblastic differentiation from bone mesenchymal stem cells

(2012) Zhu Yang et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Cistanches Herba aqueous extract affecting serum BGP and TRAP and bone marrow Smad1 mRNA, Smad5 mRNA, TGF-β1 mRNA and TIEG1 mRNA expression levels in osteoporosis disease

(2012) Hai-Dong Liang et al.   MOLECULAR BIOLOGY REPORTS

Effects of Velvet Antler with Blood on Bone in Ovariectomized Rats

(2012) Sung-Hui Tseng et al.   MOLECULES

The beneficial effect of Radix Dipsaci total saponins on bone metabolism in vitro and in vivo and the possible mechanisms of action

(2012) Y. B. Niu et al.   OSTEOPOROSIS INTERNATIONAL

Neobavaisoflavone stimulates osteogenesis via p38-mediated up-regulation of transcription factors and osteoid genes expression in MC3T3-E1 cells

(2012) Ming-Jaw Don et al.   PHYTOMEDICINE

The Chinese Pueraria root extract (Pueraria lobata) ameliorates impaired glucose and lipid metabolism in obese mice

(2012) Jeevan K. Prasain et al.   PHYTOMEDICINE

Salvianolic Acid B Prevents Bone Loss in Prednisone-Treated Rats through Stimulation of Osteogenesis and Bone Marrow Angiogenesis

(2012) Liao Cui et al.   PLoS One

Effects of the Dichloromethane Fraction of Dipsaci Radix on the Osteoblastic Differentiation of Human Alveolar Bone Marrow-Derived Mesenchymal Stem Cells

(2011) Beom-Su KIM et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Anthraquinone compounds from Morinda officinalis inhibit osteoclastic bone resorption in vitro

(2011) Leilei Bao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Icariin stimulates MC3T3-E1 cell proliferation and differentiation through up-regulation of bone morphogenetic protein-2

(2011) Ying Zhang   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Effect of Cistanches Herba Aqueous Extract on Bone Loss in Ovariectomized Rat

(2011) Haidong Liang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anti-osteoporosis activity of Cibotium barometz extract on ovariectomy-induced bone loss in rats

(2011) Xiong Zhao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antiosteoporotic compounds from seeds of Cuscuta chinensis

(2011) Lijuan Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of medicinal herb salvia miltiorrhiza on osteoblastic cells in vitro

(2011) Alice Chin et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

The Dose-Effect of Icariin on the Proliferation and Osteogenic Differentiation of Human Bone Mesenchymal Stem Cells

(2011) Jun-Jun Fan et al.   MOLECULES

Osthol, a Coumarin Isolated from Common Cnidium Fruit, Enhances the Differentiation and Maturation of Osteoblasts in vitro

(2011) Lei-Guo Ming et al.   PHARMACOLOGY

Effect of Total Glycosides from Eucommia ulmoides Seed on Bone Microarchitecture in Rats

(2011) Yang Li et al.   PHYTOTHERAPY RESEARCH

Asperosaponin VI, A Saponin Component fromDipsacus asperWall, induces Osteoblast Differentiation through Bone Morphogenetic Protein-2/p38 and Extracellular Signal-regulated Kinase 1/2 Pathway

(2011) Yinbo Niu et al.   PHYTOTHERAPY RESEARCH

Androgens and osteoporosis

(2011) Peter R Ebeling   Current Opinion in Endocrinology Diabetes and Obesity

Tanshinone IIA enhances BMP-2-stimulated commitment of C2C12 cells into osteoblasts via p38 activation

(2010) Hye Joo Kim et al.   AMINO ACIDS

Puerarin Inhibits C-Reactive Protein Expression via Suppression of Nuclear Factor κB Activation in Lipopolysaccharide-Induced Peripheral Blood Mononuclear Cells of Patients with Stable Angina Pectoris

(2010) Xiangjun Yang et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Icariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells

(2010) Sao-Keng Mok et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of bone resorption by Tanshinone VI isolated from Salvia miltiorrhiza Bunge

(2010) V. Nicolin et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Effect of icariin on bone formation during distraction osteogenesis in the rabbit mandible

(2010) H. Wei et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Icariin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro

(2010) Hui-Ping Ma et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Stimulation of osteoblastic differentiation and mineralization in MC3T3-E1 cells by antler and fermented antler using Cordyceps militaris

(2010) Hyun-Sun Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Icariin inhibits osteoclast differentiation and bone resorption by suppression of MAPKs/NF-κB regulated HIF-1α and PGE2 synthesis

(2010) Tsai-Pei Hsieh et al.   PHYTOMEDICINE

Osteogenic effects of D(+)β-3,4-dihydroxyphenyl lactic acid (salvianic acid A, SAA) on osteoblasts and bone marrow stromal cells of intact and prednisone-treated rats

(2009) Liao Cui et al.   ACTA PHARMACOLOGICA SINICA

Epimedium-derived flavonoids promote osteoblastogenesis and suppress adipogenesis in bone marrow stromal cells while exerting an anabolic effect on osteoporotic bone

(2009) Peng Songlin et al.   BONE

The constituents of Cibotium barometz and their permeability in the human Caco-2 monolayer cell model

(2009) Qi Wu et al.   JOURNAL OF ETHNOPHARMACOLOGY

The osteoprotective effect of Radix Dipsaci extract in ovariectomized rats

(2009) Zhen-Guo Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cuscuta chinensis Extract Promotes Osteoblast Differentiation and Mineralization in Human Osteoblast-Like MG-63 Cells

(2009) Hyun Mo Yang et al.   JOURNAL OF MEDICINAL FOOD

Inhibitors of Osteoclast Formation from Rhizomes ofCibotium barometz

(2009) Nguyen Xuan Cuong et al.   JOURNAL OF NATURAL PRODUCTS

Antiosteoporotic Activity of Anthraquinones from Morinda officinalis on Osteoblasts and Osteoclasts

(2009) Yan-Bin Wu et al.   MOLECULES

Inhibitory Effects of Morinda officinalis Extract on Bone Loss in Ovariectomized Rats

(2009) Nan Li et al.   MOLECULES

Puerarinprotects against ischemic brain injury in a rat model of transient focal ischemia

(2009) Li Gao et al.   NEUROLOGICAL RESEARCH

Antiosteoporotic activity of phenolic compounds from Curculigo orchioides

(2009) Lei Jiao et al.   PHYTOMEDICINE

Antiosteoporotic activity of icariin in ovariectomized rats

(2009) H. Nian et al.   PHYTOMEDICINE

Icariin isolated from Epimedium pubescens regulates osteoblasts anabolism through BMP-2, SMAD4, and Cbfa1 expression

(2009) Tsai-Pei Hsieh et al.   PHYTOMEDICINE

Icariin induces osteogenic differentiation in vitro in a BMP- and Runx2-dependent manner

(2008) Jiyuan Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bavachalcone inhibits osteoclast differentiation through suppression of NFATc1 induction by RANKL

(2008) Cheol Kyu Park et al.   BIOCHEMICAL PHARMACOLOGY

Du-Zhong (Eucommia ulmoides Oliv.) cortex extract prevent OVX-induced osteoporosis in rats

(2008) R. Zhang et al.   BONE

Ethanol extract of Psoralea corylifolia L. and its main constituent, bakuchiol, reduce bone loss in ovariectomised Sprague–Dawley rats

(2008) Sun-Hye Lim et al.   BRITISH JOURNAL OF NUTRITION

The Correlation ofSalvia miltiorrhizaExtract–Induced Regulation of Osteoclastogenesis with the Amount of Components Tanshinone I, Tanshinone IIA, Cryptotanshinone, and Dihydrotanshinone

(2008) Hae-Kyung Kim et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Protective effect of polysaccharides from morinda officinalis on bone loss in ovariectomized rats

(2008) Zhu MengYong et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Curculigo orchioides, a traditional Chinese medicinal plant, prevents bone loss in ovariectomized rats

(2008) D.P. Cao et al.   MATURITAS

Effects and safety of Pueraria mirifica on lipid profiles and biochemical markers of bone turnover rates in healthy postmenopausal women

(2008) Jittima Manonai et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY