pH and redox dual-responsive nanoparticles based on disulfide-containing poly(β-amino ester) for combining chemotherapy and COX-2 inhibitor to overcome drug resistance in breast cancer

Endoplasmic reticulum stress: major player in size-dependent inhibition of P-glycoprotein by silver nanoparticles in multidrug-resistant breast cancer cells

(2019) Mohana Krishna Gopisetty et al.   JOURNAL OF NANOBIOTECHNOLOGY

Rack1 mediates Src binding to drug transporter P-glycoprotein and modulates its activity through regulating Caveolin-1 phosphorylation in breast cancer cells

(2019) Yanling Fan et al.   Cell Death & Disease

Rational Design of Nanoparticles to Overcome Poor Tumor Penetration and Hypoxia-Induced Chemotherapy Resistance: Combination of Optimizing Size and Self-Inducing High Level of Reactive Oxygen Species

(2019) Liandong Deng et al.   ACS Applied Materials & Interfaces

Dual pH-responsive multifunctional nanoparticles for targeted treatment of breast cancer by combining immunotherapy and chemotherapy

(2018) Yuanyuan Liu et al.   Acta Biomaterialia

Nanoscaled red blood cells facilitate breast cancer treatment by combining photothermal/photodynamic therapy and chemotherapy

(2018) Guoyun Wan et al.   BIOMATERIALS

Application of hyaluronic acid as carriers in drug delivery

(2018) Gangliang Huang et al.   DRUG DELIVERY

pH- and redox-responsive nanoparticles composed of charge-reversible pullulan-based shells and disulfide-containing poly(ß-amino ester) cores for co-delivery of a gene and chemotherapeutic agent

(2018) Sipei Zhang et al.   NANOTECHNOLOGY

Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications

(2018) Wei Wu et al.   Theranostics

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016

(2018) et al.   JAMA Oncology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Regulation of Ca2+ Signaling for Drug-Resistant Breast Cancer Therapy with Mesoporous Silica Nanocapsule Encapsulated Doxorubicin/siRNA Cocktail

(2018) Shu Wang et al.   ACS Nano

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade

(2016) Zhaolin Chen et al.   CANCER LETTERS

Stepwise pH-responsive nanoparticles containing charge-reversible pullulan-based shells and poly(β-amino ester)/poly(lactic-co-glycolic acid) cores as carriers of anticancer drugs for combination therapy on hepatocellular carcinoma

(2016) Cong Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Dual-responsive nanoparticles based on oxidized pullulan and a disulfide-containing poly(β-amino) ester for efficient delivery of genes and chemotherapeutic agents targeting hepatoma

(2016) Hemei Wang et al.   Polymer Chemistry

Hematoporphyrin and doxorubicin co-loaded nanomicelles for the reversal of drug resistance in human breast cancer cells by combining sonodynamic therapy and chemotherapy

(2016) Guoyun Wan et al.   RSC Advances

Hyaluronic acid-decorated dual responsive nanoparticles of Pluronic F127, PLGA, and chitosan for targeted co-delivery of doxorubicin and irinotecan to eliminate cancer stem-like cells

(2015) Hai Wang et al.   BIOMATERIALS

Polymeric Nanostructures for Imaging and Therapy

(2015) Mahmoud Elsabahy et al.   CHEMICAL REVIEWS

Stealth CD44-targeted hyaluronic acid supramolecular nanoassemblies for doxorubicin delivery: Probing the effect of uncovalent pegylation degree on cellular uptake and blood long circulation

(2015) Xiaopeng Han et al.   JOURNAL OF CONTROLLED RELEASE

Multi-drug resistance in cancer chemotherapeutics: Mechanisms and lab approaches

(2014) Qiong Wu et al.   CANCER LETTERS

pH-sensitive pullulan-based nanoparticle carrier for adriamycin to overcome drug-resistance of cancer cells

(2014) Hua Guo et al.   CARBOHYDRATE POLYMERS

P-glycoprotein associates with Anxa2 and promotes invasion in multidrug resistant breast cancer cells

(2013) Fei Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery

(2013) Ru Cheng et al.   BIOMATERIALS

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

Nanoparticle-based combination therapy toward overcoming drug resistance in cancer

(2012) Che-Ming Jack Hu et al.   BIOCHEMICAL PHARMACOLOGY

Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells

(2011) Feng Wang et al.   ACS Nano

COX-2 contributes to P-glycoprotein-mediated multidrug resistance via phosphorylation of c-Jun at Ser63/73 in colorectal cancer

(2011) Hua Sui et al.   CARCINOGENESIS

Glutathione-responsive nano-vehicles as a promising platform for targeted intracellular drug and gene delivery

(2011) Ru Cheng et al.   JOURNAL OF CONTROLLED RELEASE

Preventing chemoresistance of human breast cancer cell line, MCF-7 with celecoxib

(2010) Chen Chen et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Inhibition of angiogenesis- and inflammation-inducing factors in human colon cancer cells in vitro and in ovo by free and nanoparticle-encapsulated redox dye, DCPIP

(2010) Fadee G Mondalek et al.   JOURNAL OF NANOBIOTECHNOLOGY

ABC transporters: the power to change

(2009) Douglas C. Rees et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE