Targeted delivery of antibiotics to the infected pulmonary tissues using ROS-responsive nanoparticles

Vibrio cholerae OmpU Mediates CD36-Dependent Reactive Oxygen Species Generation Triggering an Additional Pathway of MAPK Activation in Macrophages

(2019) G. V. R. Krishna Prasad et al.   JOURNAL OF IMMUNOLOGY

Strongly Enhanced Antibacterial Action of Copper Oxide Nanoparticles with Boronic Acid Surface Functionality

(2019) Ahmed F. Halbus et al.   ACS Applied Materials & Interfaces

PEGylated Self-Assembled Nano-Bacitracin A: Probing the Antibacterial Mechanism and Real-Time Tracing of Target Delivery in Vivo

(2018) Wei Hong et al.   ACS Applied Materials & Interfaces

PEGylation of Tobramycin Improves Mucus Penetration and Antimicrobial Activity against Pseudomonas aeruginosa Biofilms in Vitro

(2018) Tania F. Bahamondez-Canas et al.   MOLECULAR PHARMACEUTICS

Advances in targeting the folate receptor in the treatment/imaging of cancers

(2018) Marcos Fernández et al.   Chemical Science

BAR-encapsulated nanoparticles for the inhibition and disruption of Porphyromonas gingivalis–Streptococcus gordonii biofilms

(2018) Mohamed Y. Mahmoud et al.   JOURNAL OF NANOBIOTECHNOLOGY

Oxidation-Responsive Materials: Biological Rationale, State of the Art, Multiple Responsiveness, and Open Issues

(2018) Farah El-Mohtadi et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Role of Reactive Oxygen Species (ROS) in Therapeutics and Drug Resistance in Cancer and Bacteria

(2017) Allimuthu T. Dharmaraja   JOURNAL OF MEDICINAL CHEMISTRY

Promoting Vaginal Distribution of E7 and MCL-1 siRNA-Silencing Nanoparticles for Cervical Cancer Treatment

(2017) Anna Lechanteur et al.   MOLECULAR PHARMACEUTICS

The Role of Reactive Oxygen Species in Antibiotic-Mediated Killing of Bacteria

(2017) Heleen Van Acker et al.   TRENDS IN MICROBIOLOGY

Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

(2017) Craig S. Schneider et al.   Science Advances

A superoxide dismutase/catalase mimetic nanomedicine for targeted therapy of inflammatory bowel disease

(2016) Qixiong Zhang et al.   BIOMATERIALS

Biofilms: an emergent form of bacterial life

(2016) Hans-Curt Flemming et al.   NATURE REVIEWS MICROBIOLOGY

Mechanisms of bacterial persistence during stress and antibiotic exposure

(2016) Alexander Harms et al.   SCIENCE

Effect of PEG and water-soluble chitosan coating on moxifloxacin-loaded PLGA long-circulating nanoparticles

(2016) Sanaul Mustafa et al.   Drug Delivery and Translational Research

Folate Receptor-Targeted Diagnostics and Therapeutics for Inflammatory Diseases

(2016) Young-Su Yi   Immune Network

Transcription Factors That Defend Bacteria Against Reactive Oxygen Species

(2015) James A. Imlay   Annual Review of Microbiology

Antimicrobial efficacy of tobramycin polymeric nanoparticles for Pseudomonas aeruginosa infections in cystic fibrosis: Formulation, characterisation and functionalisation with dornase alfa (DNase)

(2015) Jill Deacon et al.   JOURNAL OF CONTROLLED RELEASE

Current Approaches for Improving Intratumoral Accumulation and Distribution of Nanomedicines

(2015) Mikhail O Durymanov et al.   Theranostics

Topical Ocular Drug Delivery to the Back of the Eye by Mucus-Penetrating Particles

(2015) Lisa R. Schopf et al.   Translational Vision Science & Technology

Opposite effects of cefoperazone and ceftazidime on S-ribosylhomocysteine lyase/autoinducer-2 quorum sensing and biofilm formation by an Escherichia coli clinical isolate

(2014) HUI-QING SHI et al.   Molecular Medicine Reports

Classical versus alternative macrophage activation: the Ying and the Yang in host defense against pulmonary fungal infections

(2014) C M Leopold Wager et al.   Mucosal Immunology

Biocompatible Reactive Oxygen Species (ROS)-Responsive Nanoparticles as Superior Drug Delivery Vehicles

(2014) Dinglin Zhang et al.   Advanced Healthcare Materials

Exploiting Oxidative Microenvironments in the Body as Triggers for Drug Delivery Systems

(2013) Shivanjali Joshi-Barr et al.   ANTIOXIDANTS & REDOX SIGNALING

Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections

(2013) M Guilliams et al.   Mucosal Immunology

Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections

(2013) Pavan Puligujja et al.   Nanomedicine-Nanotechnology Biology and Medicine

Oxidative stress in vascular disease and its pharmacological prevention

(2013) Huige Li et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Biocompatible Polymeric Nanoparticles Degrade and Release Cargo in Response to Biologically Relevant Levels of Hydrogen Peroxide

(2012) Caroline de Gracia Lux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

(2010) Alessandro Luciani et al.   NATURE CELL BIOLOGY

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages

(2008) W. Xia et al.   BLOOD

Pharmacokinetics and Biodistribution of Nanoparticles

(2008) Shyh-Dar Li et al.   MOLECULAR PHARMACEUTICS

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology

Efficient drug targeting to rat alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into mannosylated liposomes for treatment of respiratory intracellular parasitic infections

(2007) Sumio Chono et al.   JOURNAL OF CONTROLLED RELEASE