Cooperativity between the 3’ untranslated region microRNA binding sites is critical for the virulence of eastern equine encephalitis virus

Rational design of a live-attenuated eastern equine encephalitis virus vaccine through informed mutation of virulence determinants

(2019) Derek W. Trobaugh et al.   PLoS Pathogens

Innate Control of Adaptive Immunity: Beyond the Three-Signal Paradigm

(2017) Aakanksha Jain et al.   JOURNAL OF IMMUNOLOGY

MicroRNA Regulation of RNA Virus Replication and Pathogenesis

(2017) Derek W. Trobaugh et al.   TRENDS IN MOLECULAR MEDICINE

A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration

(2016) Troels K.H. Scheel et al.   Cell Host & Microbe

Host translation shutoff mediated by non-structural protein 2 is a critical factor in the antiviral state resistance of Venezuelan equine encephalitis virus

(2016) Nishank Bhalla et al.   VIROLOGY

The 17D-204 Vaccine Strain-Induced Protection against Virulent Yellow Fever Virus Is Mediated by Humoral Immunity and CD4+ but not CD8+ T Cells

(2016) Alan M. Watson et al.   PLoS Pathogens

Hepatitis C Virus RNA Functionally Sequesters miR-122

(2015) Joseph M. Luna et al.   CELL

Human miR-3145 inhibits influenza A viruses replication by targeting and silencing viral PB1 gene

(2015) Kritsada Khongnomnan et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

miR-28-3p Is a Cellular Restriction Factor That Inhibits Human T Cell Leukemia Virus, Type 1 (HTLV-1) Replication and Virus Infection

(2015) Xue Tao Bai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The microRNA miR-485 targets host and influenza virus transcripts to regulate antiviral immunity and restrict viral replication

(2015) Harshad Ingle et al.   Science Signaling

The 5′ and 3′ ends of alphavirus RNAs – Non-coding is not non-functional

(2015) Jennifer L. Hyde et al.   VIRUS RESEARCH

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

The microRNA miR-485 targets host and influenza virus transcripts to regulate antiviral immunity and restrict viral replication

(2015) Harshad Ingle et al.   Science Signaling

Field Investigations of Winter Transmission of Eastern Equine Encephalitis Virus in Florida

(2014) Andrea M. Bingham et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

mRNA Destabilization Is the Dominant Effect of Mammalian MicroRNAs by the Time Substantial Repression Ensues

(2014) Stephen W. Eichhorn et al.   MOLECULAR CELL

Silencing of neurotropic flavivirus replication in the central nervous system by combining multiple microRNA target insertions in two distinct viral genome regions

(2014) Natalya L. Teterina et al.   VIROLOGY

MicroRNA-23b Inhibits Enterovirus 71 Replication through Downregulation of EV71 VPl Protein

(2013) Bai-ping Wen et al.   INTERVIROLOGY

Stable, High-Level Expression of Reporter Proteins from Improved Alphavirus Expression Vectors To Track Replication and Dissemination during Encephalitic and Arthritogenic Disease

(2013) C. Sun et al.   JOURNAL OF VIROLOGY

Human MicroRNA hsa-miR-296-5p Suppresses Enterovirus 71 Replication by Targeting the Viral Genome

(2013) Z. Zheng et al.   JOURNAL OF VIROLOGY

RNA viruses can hijack vertebrate microRNAs to suppress innate immunity

(2013) Derek W. Trobaugh et al.   NATURE

MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies

(2013) Ryan A Langlois et al.   NATURE BIOTECHNOLOGY

Argonaute proteins: functional insights and emerging roles

(2013) Gunter Meister   NATURE REVIEWS GENETICS

Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis

(2012) A. Mildner et al.   BLOOD

MicroRNA Targeting of Neurotropic Flavivirus: Effective Control of Virus Escape and Reversion to Neurovirulent Phenotype

(2012) B. L. Heiss et al.   JOURNAL OF VIROLOGY

Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex

(2012) T. Shimakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses

(2012) Ryan A. Langlois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Replication in Cells of Hematopoietic Origin Is Necessary for Dengue Virus Dissemination

(2012) Alissa M. Pham et al.   PLoS Pathogens

Heparan sulfate binding by natural eastern equine encephalitis viruses promotes neurovirulence

(2011) C. L. Gardner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular MicroRNAs Inhibit Replication of the H1N1 Influenza A Virus in Infected Cells

(2010) L. Song et al.   JOURNAL OF VIROLOGY

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Virulence variation among isolates of western equine encephalitis virus in an outbred mouse model

(2009) C. H. Logue et al.   JOURNAL OF GENERAL VIROLOGY

Type I interferon induction is correlated with attenuation of a South American eastern equine encephalitis virus strain in mice

(2009) Christina L. Gardner et al.   VIROLOGY

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Structural and Nonstructural Protein Genome Regions of Eastern Equine Encephalitis Virus Are Determinants of Interferon Sensitivity and Murine Virulence

(2008) P. V. Aguilar et al.   JOURNAL OF VIROLOGY

Eastern and Venezuelan Equine Encephalitis Viruses Differ in Their Ability To Infect Dendritic Cells and Macrophages: Impact of Altered Cell Tropism on Pathogenesis

(2008) C. L. Gardner et al.   JOURNAL OF VIROLOGY