Resurrection of the ancestral RH5 invasion ligand provides a molecular explanation for the origin of P. falciparum malaria in humans

Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites

(2019) Ellen Knuepfer et al.   PLoS Pathogens

Malaria Vaccines: Recent Advances and New Horizons

(2018) Simon J. Draper et al.   Cell Host & Microbe

Genome-scale identification of cellular pathways required for cell surface recognition

(2018) Sumana Sharma et al.   GENOME RESEARCH

Adaptive Evolution of RH5 in Ape Plasmodium species of the Laverania Subgenus

(2018) Lindsey J. Plenderleith et al.   mBio

Multiple Selected Changes May Modulate the Molecular Interaction between Laverania RH5 and Primate Basigin

(2018) Diego Forni et al.   mBio

Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria

(2018) Thomas D. Otto et al.   Nature Microbiology

Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex

(2018) Wilson Wong et al.   NATURE

P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5

(2017) Francis Galaway et al.   Nature Communications

Multigenomic Delineation ofPlasmodiumSpecies of theLaveraniaSubgenus Infecting Wild-Living Chimpanzees and Gorillas

(2016) Weimin Liu et al.   Genome Biology and Evolution

The host specificity of ape malaria parasites can be broken in confined environments

(2016) Barthélémy Ngoubangoye et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Ape malaria transmission and potential for ape-to-human transfers in Africa

(2016) Boris Makanga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomes of cryptic chimpanzee Plasmodium species reveal key evolutionary events leading to human malaria

(2016) Sesh A. Sundararaman et al.   Nature Communications

Basigin is a druggable target for host-oriented antimalarial interventions

(2015) Zenon A. Zenonos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial forPlasmodium falciparumerythrocyte invasion

(2015) K. Sony Reddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The origins of malaria: there are more things in heaven and earth …

(2014) P. J. KEELING et al.   PARASITOLOGY

A Library of Functional Recombinant Cell-surface and SecretedP. falciparumMerozoite Proteins

(2013) Cécile Crosnier et al.   MOLECULAR & CELLULAR PROTEOMICS

Various PfRH5 polymorphisms can support Plasmodium falciparum invasion into the erythrocytes of owl monkeys and rats

(2013) Karen Hayton et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

RH5-Basigin interaction plays a major role in the host tropism of Plasmodium falciparum

(2013) M. Wanaguru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Great Apes and Zoonoses

(2013) P. M. Sharp et al.   SCIENCE

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

(2012) Magnus Manske et al.   NATURE

Semaphorin-7A Is an Erythrocyte Receptor for P. falciparum Merozoite-Specific TRAP Homolog, MTRAP

(2012) S. Josefin Bartholdson et al.   PLoS Pathogens

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum

(2011) Cécile Crosnier et al.   NATURE

An EGF-like Protein Forms a Complex with PfRh5 and Is Required for Invasion of Human Erythrocytes by Plasmodium falciparum

(2011) Lin Chen et al.   PLoS Pathogens

Origin of the human malaria parasite Plasmodium falciparum in gorillas

(2010) Weimin Liu et al.   NATURE

Erythrocyte Binding Protein PfRH5 Polymorphisms Determine Species-Specific Pathways of Plasmodium falciparum Invasion

(2008) Karen Hayton et al.   Cell Host & Microbe

Large-scale screening for novel low-affinity extracellular protein interactions

(2008) K. M. Bushell et al.   GENOME RESEARCH

Reticulocyte-binding protein homologue 5 – An essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum

(2008) Jake Baum et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Global trends in emerging infectious diseases

(2008) Kate E. Jones et al.   NATURE