Article
Pharmacology & Pharmacy
Thi Tuong Vi Truong, Chien-Chang Chen, Selvaraj Rajesh Kumar, Chih-Chien Hu, Dave W. Chen, Yu-Kuo Liu, Shingjiang Jessie Lue
Summary: Spherical silver nanoparticles and silver nanoprisms were synthesized and decorated on graphene oxide nanosheets, showing promising antibacterial properties against Gram-positive bacteria, especially at high concentrations. The levels of reactive oxygen species produced in the bacteria-nanomaterial mixtures were highly correlated to the antibacterial efficacy values.
Review
Biochemistry & Molecular Biology
Fabio Busato, Badr El Khouzai, Maddalena Mognato
Summary: Ionizing radiation is a well-established method for cancer treatment, but some tumors are resistant to radiotherapy. By considering tumor genetics/epigenetics, tumor microenvironment, tumor metabolism, and the presence of non-malignant cells, clinical strategies targeting radioresistant tumors can be improved.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Ian Delahunty, Jianwen Li, Wen Jiang, Chaebin Lee, Xueyuan Yang, Anil Kumar, Zhi Liu, Weizhong Zhang, Jin Xie
Summary: This study explores a radiosensitizer, 7-DHC, which can react with radiation-induced reactive oxygen species and promote lipid peroxidation, DNA double-strand breaks, and mitochondrial damage in cancer cells. By encapsulating into PLGA nanoparticles, 7-DHC shows efficient delivery and significantly enhances the efficacy of radiotherapy, leading to tumor eradication without side effects.
Review
Biochemistry & Molecular Biology
Silvia Pomella, Antonella Porrazzo, Matteo Cassandri, Simona Camero, Silvia Codenotti, Luisa Milazzo, Francesca Vulcano, Giovanni Barillari, Giovanni Cenci, Cinzia Marchese, Alessandro Fanzani, Francesca Megiorni, Rossella Rota, Francesco Marampon
Summary: This review summarizes the classification and management of rhabdomyosarcoma, with a focus on radiotherapy treatment and possible radiosensitizing strategies. It is found that rhabdomyosarcoma has radioresistance, and further studies are needed to dissect the molecular mechanisms of radioresistance in order to improve the efficacy of radiotherapy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Engineering, Manufacturing
Muhammad Wajahat, Sanghyeon Lee, Jung Hyun Kim, Jinhyuck Ahn, Ho Hyung Sim, Je Hyeong Kim, Jongcheon Bae, Seong Hyeon Kim, Jaeyeon Pyo, Seung Kwon Seol
Summary: Functionalized graphene with inorganic nanomaterials has enhanced electrical and electrochemical properties. 3D printing is used to fabricate silver nanoparticle-decorated graphene microarchitectures, showing potential applications in flexible electronic devices.
ADDITIVE MANUFACTURING
(2022)
Article
Biotechnology & Applied Microbiology
Lidan Hou, Ting Zhong, Peng Cheng, Bohan Long, Leilei Shi, Xiangjun Meng, Han Yao
Summary: This study developed a self-assembled nanoparticle loaded with paclitaxel, which was targeted to colorectal cancer using a specific binding peptide. The nanoparticle showed improved intracellular internalization, enhanced tumor cytotoxicity, and reduced systemic toxicity, suggesting a promising approach for targeted drug delivery in colorectal cancer treatment.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Medicine, Research & Experimental
Jihui Wang, He Zhao, Wenjing Song, Mingyang Gu, Yujia Liu, Bingnan Liu, Honglei Zhan
Summary: The article introduces a promising multifunctional nanocarrier that integrates chemotherapy and photothermal therapy to enhance anticancer efficacy, sensitize drug-resistant cancer cells, and diminish cancer stem cells.
MOLECULAR PHARMACEUTICS
(2022)
Article
Chemistry, Physical
Chao Lu, Xi Chen
Summary: A study on silver nanoparticles decorated graphene composites as electrode materials for efficient electrochemical energy storage was reported, showing high specific capacity and excellent cycling stability.
CHEMICAL PHYSICS LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Chao Ji, Maoru Zhao, Chengyan Wang, Ruixue Liu, Shuang Zhu, Xinghua Dong, Chunjian Su, Zhanjun Gu
Summary: This study proposes a new treatment method using poly(vinylpyrrolidone) coated Ta nanoparticles for combined radiotherapy and photothermal therapy to treat both the primary tumor and metastatic sentinel lymph nodes in breast carcinoma. The nanoparticles deposit high radiation doses within the tumor and effectively deliver to the lymph nodes, improving the treatment outcome.
Article
Chemistry, Multidisciplinary
Joselyn Benalcazar, Esteban D. Lasso, Carolina M. Ibarra-Barreno, Jose Andres Arcos Pareja, Nelson Santiago Vispo, Julio C. Chacon-Torres, Sarah Briceno
Summary: This study investigates how to optimize the antibacterial properties of nano-composites by varying the irradiation wavelength during the synthesis process. The authors transformed silver nanoparticles into narrow-sized anisotropically flat silver nanoprisms and anchored them to graphene oxide. They found a synergistic effect between the silver nanoprisms and the oxygen functional groups of the graphene oxide, resulting in enhanced antibacterial activity of the nanocomposite.
Article
Nanoscience & Nanotechnology
Shuo-Fu Chen, Min Kau, Yu-Chi Wang, Ming -Hong Chen, Fu- Tung, Mei-Hsiu Chen, Tse-Ying Liu
Summary: This study demonstrates that the combination of gold-core silica-shell nanoparticles (Au@SiO2 NPs) and low-dose radiation can enhance the clinical efficacy of immune checkpoint inhibitors in glioblastoma treatment. The synergistic strategy modulates tumor microenvironments, increases systemic antitumor immunity, and improves the prognosis for patients with brain tumors.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Article
Engineering, Chemical
Nozha M. Sawan, Abeer A. Alshami, Alhanoof Aldegheishem, Eman Alsagob
Summary: This study aimed to modify orthodontic adhesive using graphene sheets decorated with silver nanoparticles (Ag-GS) in order to examine their mechanical and antibacterial properties after bonding with orthodontic brackets. The results showed that the improved adhesive with 0.35 wt% Ag-GS significantly enhanced the antibacterial capability and had no cytotoxicity effect on cells after 72 hours. It also showed promising results for bonding orthodontic brackets to enamel.
INTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES
(2022)
Article
Chemistry, Physical
Yaping Feng, Haoyu Dai, Yi Zhang, Jianjun Chen, Fengxiang Chen, Lei Jiang
Summary: The study introduces a silver nanoparticles decorated graphene oxide membrane for enhanced photo-driven ionic transport, utilizing asymmetric light stimulated charge carrier dynamics to strengthen ion-driven force. This concept has the potential to stimulate broader research in sensing, energy storage and conversion, and water treatment within two-dimensional layered membranes, based on the interactions of plasmon-enhanced photo-driven ion transport.
Article
Chemistry, Multidisciplinary
Chiara Amicucci, Cristiano D'Andrea, Marella de Angelis, Martina Banchelli, Roberto Pini, Paolo Matteini
Summary: This paper introduces a graphene paper-supported plasmonic substrate for biodetection, which provides stable SERS signals at sub-millimolar concentration and a detection limit down to the nanogram level in the case of hemoglobin. The presence of a graphene underlayer ensures an even surface distribution of SERS hotspots and improved stability of the SERS signal.
Article
Pharmacology & Pharmacy
Venu Yakati, Swathi Vangala, Rajkumar Banerjee, Gopikrishna Moku, Vijay Sagar Madamsetty
Summary: The CPK-PTX-NPs nano delivery system effectively targets colorectal cancer cells with enhanced therapeutic efficacy, demonstrating significant potential for cancer treatment.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Physical
Igor Khmelinskii, Vladimir Makarov
Article
Chemistry, Multidisciplinary
Igor Khmelinskii, Vladimir Makarov
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
(2020)
Article
Chemistry, Physical
Carolina Rojas-Michea, Mauricio Morel, Francisco Gracia, Gerardo Morell, Edgar Mosquera
SURFACES AND INTERFACES
(2020)
Article
Chemistry, Multidisciplinary
Shyam Sutariya, Mohammed Bsatee, Olesia Gololobova, Daysi Diaz-Diestra, Bibek Thapa, Brad R. Weiner, Gerardo Morell, Wojciech M. Jadwisienczak, Juan Beltran-Huarac
Summary: The study investigated the magnetic control of Mn photoluminescence in Fe3O4/L-cys ZnS:Mn nanocomposites, revealing a promising bifunctional material with good fluorescence and magnetic properties for biomedical applications and quantum computing elements.
Article
Energy & Fuels
Balram Tripathi, Rajesh K. Katiyar, Gerardo Morell, Ambesh Dixit, Ram S. Katiyar
Summary: Efficient coupling of BiFeO3 in the C-S composite cathode improves the cyclic performance and capacity of Li-S batteries by reducing the polysulfide shuttle effect. The built-in internal field due to BFO enhances polysulfide trapping, leading to more efficient trapping compared to pristine C-S composite cathodes. XRD results show an orthorhombic structure in BFO-C-S composite cathodes, while Raman spectra and SEM images confirm the efficient coupling of BFO in C-S composites.
Article
Chemistry, Multidisciplinary
Sandra Rodriguez-Villanueva, Frank Mendoza, Alvaro A. Instan, Ram S. Katiyar, Brad R. Weiner, Gerardo Morell
Summary: This study reports the direct synthesis of graphene on SiO2/Si using hot-filament chemical vapor deposition. The results show the growth of few-layers of graphene over the entire SiO2/Si substrate, far beyond the catalytic copper-strip.
Meeting Abstract
Biochemistry & Molecular Biology
Anna C. Martinez Guadalupe, Brad Weiner, Gerardo Morell, Nataniel Medina, Wenndy Pantoja, Alexis Lavin
Article
Chemistry, Multidisciplinary
Sandra Rodriguez-Villanueva, Frank Mendoza, Brad R. Weiner, Gerardo Morell
Summary: This study presents a method to grow graphene on a 6H-SiC substrate using the hot filament chemical vapor deposition technique. The graphene films were analyzed using various techniques, such as Raman spectroscopy and scanning electron microscopy, and it was found that few-layer and multilayer graphene were deposited. Compositional analysis confirmed the deposition of graphene on SiC substrates without any metal involvement.
Article
Multidisciplinary Sciences
Pradipta Ranjan Rauta, Yuri Mackeyev, Keith Sanders, Joseph B. K. Kim, Valeria V. Gonzalez, Yasmin Zahra, Muhammad A. Shohayeb, Belal Abousaida, Geraldine V. Vijay, Okan Tezcan, Paul Derry, Anton V. Liopo, Eugene R. Zubarev, Rickey Carter, Pankaj Singh, Sunil Krishnan
Summary: This article investigates gold nanorods with a responsive epilayer that can transform into cell-penetrating particles in the acidic tumor microenvironment. The study finds that when administered intravenously in mice, these nanorods can accumulate in tumors without causing significant harm to animal health, and they can effectively enhance the efficacy of radiation therapy for tumors.
Article
Environmental Sciences
Abelardo Colon, Javier Avalos, Brad R. Weiner, Gerardo Morell, Rafael Rios
Summary: Filtration technology is crucial for reducing waterborne diseases caused by poor water quality. Nanomaterials can address the challenges of filtration technology by modifying membrane properties. This study explores the use of nanodiamond particles with surface functionality and bio-compatibility for filtration treatments.
JOURNAL OF WATER AND HEALTH
(2023)
Article
Biochemistry & Molecular Biology
Mohan K. Bhattarai, Moses D. Ashie, Sita Dugu, Kiran Subedi, Bishnu P. Bastakoti, Gerardo Morell, Ram S. Katiyar
Summary: Iron oxide nanoparticles (IONPs) were successfully synthesized via a block copolymer-assisted hydrothermal method, and their phase purity and crystal structure were analyzed by X-ray diffraction. The study revealed that the synthesized IONPs exhibited hexagonal phase symmetry of alpha-Fe2O3. Raman analysis and magnetic measurements further confirmed the characteristic features and superparamagnetic behavior of the nanoparticles. Additionally, the study demonstrated the effective adsorption of Congo red (CR) by IONPs, making them potential candidates for wastewater treatment and catalytic applications.
Article
Nanoscience & Nanotechnology
Rajesh K. K. Katiyar, Claudia C. Zuluaga C. Gomez, Swati Katiyar, Balram Tripathi, Gerardo Morell, Brad R. R. Weiner, Ram S. Katiyar
Summary: In this manuscript, the role of ferroelectric nanoparticles (FNPs) coated separators in capacity retention at high current density on S/SWCNT composite cathodes is reported. FNPs coated separators showed a capacity retention improvement of more than 100%, while commercial separator polypropylene (PP) had a retention rate of 72%. The FNPs coated separator acted as a repulsive charge on the separator surface to retard polysulfide migration and protected the surface of lithium from dendrite formation, resulting in higher capacity retention and stability.
Article
Chemistry, Multidisciplinary
Claudia C. Zuluaga-Gomez, Christian O. Plaza-Rivera, Balram Tripathi, Rajesh K. Katiyar, Dhiren K. Pradhan, Gerardo Morell, Yi Lin, Margarita Correa, Ram S. Katiyar
Summary: A composite cathode material of sulfur/ferroelectric nanoparticles/holey graphene (S/FNPs/hG) was fabricated to address the limitations of capacity fading in high-mass-loading Li-S batteries. The unique structure of holey graphene enables fast electron and ion transport within the electrode while mitigating volume expansion. Additionally, the ferroelectric polarization induced by FNPs effectively reduces the shuttling effect. The S/FNPs/hG composite cathodes exhibit sustainable high specific capacity, reliable cycle performance, and superior rate capability for potential commercial applications.
Article
Electrochemistry
Claudia C. C. Zuluaga-Gomez, Balram Tripathi, Christian O. O. Plaza-Rivera, Rajesh K. K. Katiyar, Margarita Correa, Dhiren K. K. Pradhan, Gerardo Morell, Ram S. S. Katiyar
Summary: This study investigates the impact of incorporating ferroelectric nanoparticles into the cathodes of lithium-sulfur batteries. The results show that the inclusion of ferroelectric nanoparticles can reduce the formation of polysulfides and improve the cycling response and stability of the batteries, leading to high performance.
Article
Chemistry, Physical
Flavia P. N. Inbanathan, Katherine Leslee A. Cimatu, David C. C. Ingram, Uriel Joseph Erasquin, Kiran Dasari, Muhammad Shehzad Sultan, Muhammad Sajjad, Vladimir Makarov, Brad R. R. Weiner, Gerardo Morell, Payman Sharifi Abdar, Wojciech M. M. Jadwisienczak
Summary: This study demonstrates the room-temperature paramagnetism in graphene quantum dots doped with nitrogen up to 3.26%. The synthesized nitrogen-doped graphene quantum dots were carefully characterized for their morphology, optical properties, and magnetic behavior using various techniques. The results show a hexagonal crystalline structure and the presence of pyridinic nitrogen configuration, which exhibits paramagnetic behavior at room temperature with a magnetization of 20.8 emu/g.