Article
Medicine, General & Internal
Agnes Holtkamp, Karim Elhennawy, Jose E. Cejudo Grano de Oro, Joachim Krois, Sebastian Paris, Falk Schwendicke
Summary: This study aimed to train deep convolutional neural networks to detect caries lesions on Near-Infrared Light Transillumination (NILT) imagery obtained either in vitro or in vivo and to assess the models' generalizability. The results showed that models trained and tested on in vivo data performed significantly better than those trained and tested on in vitro data. When tested in vitro, the models trained in vivo showed significantly lower accuracy, and similarly, when tested in vivo, models trained in vitro showed significantly lower accuracy.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Dentistry, Oral Surgery & Medicine
Mila Janjic Rankovic, Svetlana Kapor, Yegane Khazaei, Alexander Crispin, Ina Schuler, Felix Krause, Kim Ekstrand, Stavroula Michou, Florin Eggmann, Adrian Lussi, Marie-Charlotte Huysmans, Klaus Neuhaus, Jan Kuhnisch
Summary: This systematic review and meta-analysis aimed to evaluate the diagnostic accuracy and reliability of commonly used caries detection methods for proximal caries diagnostics. LF showed higher AUC values for overall caries detection and dentin caries detection than other methods, indicating a need for high-quality, well-designed caries diagnostic studies in the future.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Medicine, General & Internal
Gian Andrea Pelliccioni, Maria Rosaria Antonella Gatto, Silvia Bolognesi, Daniele Dal Fiume, Maicon Sebold, Lorenzo Breschi
Summary: The study evaluated the accuracy and efficiency of DIFOTI in detecting approximal caries in posterior teeth compared to intra-oral examination and bitewing radiographs. Results showed that DIFOTI was accurate and faster than traditional methods, highlighting its clinical relevance for caries diagnosis.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Medicine, General & Internal
Richard Macey, Tanya Walsh, Philip Riley, Richard Hogan, Anne-Marie Glenny, Helen Worthington, Janet E. Clarkson, David Ricketts
Summary: This study evaluated the diagnostic accuracy of different illumination tests for detecting enamel caries in children or adults. The results showed that Optical Coherence Tomography (OCT) demonstrated superior sensitivity, although further research and development are needed. While Near-Infrared (NIR) and Fibre-Optic devices are more readily available and easy to use, they have limitations in detecting enamel caries.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Medicine, General & Internal
Yihua Zhu, Chung Ng, Oanh Le, Yi-Ching Ho, Daniel Fried
Summary: The aim of this clinical study was to compare the diagnostic performance of dual short wavelength infrared (SWIR) occlusal transillumination and reflectance multispectral imaging with conventional visual assessment and radiography for caries detection. The study showed that SWIR imaging had higher sensitivity for caries detection on proximal and occlusal surfaces compared to conventional methods. Reflectance imaging at 1600 nm was more sensitive and specific than transillumination at 1300 nm. The combined SWIR methods had higher specificity but lower sensitivity than each individual method.
Article
Dentistry, Oral Surgery & Medicine
Friederike Litzenburger, Gerrit Schaefer, Reinhard Hickel, Jan Kuehnisch, Katrin Heck
Summary: The study found that NIRT, LF and ACIS had high sensitivity for the detection of occlusal caries, and LF and ACIS showed improved diagnostic performance when used as adjunct methods to visual examination.
Review
Dentistry, Oral Surgery & Medicine
Svetlana Kapor, Mila Janjic Rankovic, Yegane Khazaei, Alexander Crispin, Ina Schueler, Felix Krause, Adrian Lussi, Klaus Neuhaus, Florin Eggmann, Stavroula Michou, Kim Ekstrand, Marie-Charlotte Huysmans, Jan Kuehnisch
Summary: This study aimed to assess the diagnostic performance of commonly used methods for occlusal caries diagnostics. Results showed significant differences in specificity (SP) between methods under laboratory conditions, and visual examination (VE) had lower areas under ROC curves (AUCs). Under clinical conditions, VE had higher sensitivity (SE) than specificity (SP).
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Rangel Teles Freire, Agnaldo Rocha Prata-Junior, John Nadson Andrade Pinho, Wilton Mitsunari Takeshita
Summary: This study evaluated the diagnostic accuracy of caries and periapical lesions using monitors with and without DICOM-GSDF calibration under different ambient light conditions. The results showed that both calibrated and non-calibrated monitors had similar accuracy values. The different ambient light conditions did not significantly affect the diagnosis of caries lesions, but moderate ambient lighting provided the best diagnostic accuracy for periapical lesions.
JOURNAL OF DIGITAL IMAGING
(2022)
Article
Oncology
Ana Paula Marcal Marcondes, Priscila Hernandez de Campos, Caroline Santos Ribeiro, Tatiane Fernandes de Novaes, Adrian Lussi, Michele Baffi Diniz
Summary: This study compared the performance of different methods in detecting occlusal caries lesions in deciduous molars. The results showed that NILT technology and LFpen exhibited similar performance compared to the ICDAS criteria.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2023)
Article
Medicine, General & Internal
Muna Mohamed Nur, Lydia Vazquez, Clara Anton Y. Otero, Caroline Giacobino, Ivo Krejci, Marwa Abdelaziz
Summary: The aim of this study was to evaluate the reliability of three diagnostic methods (NIRT, BW, and CI) for detecting occlusal carious lesions in a low caries risk population. Results showed that visual examination and NIRT were more effective in detecting occlusal early lesions, while BW scores primarily indicated sound surfaces. Overall, NIRT combined with clinical examination was found to be suitable for detecting and monitoring early enamel caries on occlusal surfaces in low caries-risk populations.
Article
Medicine, General & Internal
Elena Minuesa-Garcia, Jose Enrique Iranzo-Cortes, Teresa Almerich-Torres, Carlos Bellot-Arcis, Jose Maria Montiel-Company, Jose Manuel Almerich-Silla
Summary: In this study, the efficacy and diagnostic concordance of ICDAS, radiographic criterion, and DIAGNOdent fluorescence laser pen were compared for occlusal caries lesions. The results showed that ICDAS and DIAGNOdent were better diagnostic methods than radiographic criterion, and the combination of these methods improved sensitivity.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Nazan Kocak-Topbas, Kivanc Kamburoglu, Ayse Tugba Ertuerk-Avunduk, Mehmet Ozgur Ozemre, Nejlan Eratam, Esra Ece cakmak
Summary: The aim of this study was to compare the diagnostic performance of various methods (ICDAS II, PR, NIR-LT, LF) with Micro-CT in detecting non-cavitated occlusal enamel and dentin caries. The results showed that NIR-LT had the highest sensitivity and accuracy for enamel caries, while LF had the highest sensitivity and accuracy for dentin caries. The ROC curve values indicated moderate diagnostic performance for all methods. Therefore, NIR-LT and LF-Pen were determined to be the most effective methods for detecting occlusal enamel and dentin caries, respectively.
Article
Dentistry, Oral Surgery & Medicine
Jingwei Cao, Yuwen Fang, Yue Liao, Yan Wang, Ran Yang, Yang Zhang, Qiong Zhang, Jing Zou
Summary: NIRI showed higher sensitivity and lower specificity compared with VI in detecting proximal caries in primary molars. Therefore, it is recommended to use NIRI in combination with BWR to improve the detection rate of proximal caries in primary molars.
JOURNAL OF DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Zvi Metzger, Dana G. Colson, Peggy Bown, Timo Weihard, Ingo Baresel, Tim Nolting
Summary: The study compared the effectiveness of near-infrared light reflection (NILR) and bitewing radiography (BWR) in detecting proximal caries. NILR was found to be more sensitive in detecting early enamel lesions compared to BWR, and comparable in detecting lesions involving the dentino-enamel junction (DEJ). Expert team showed higher accuracy in caries detection using both methods.
JOURNAL OF DENTISTRY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Humeyra Tercanli Alkis, Samed Satir, Damla Kirici, Cagatay Barutcugil
Summary: This in vitro study compared the diagnostic outcomes of caries detection in premolar and molar teeth using grayscale images and the Java-based software pseudocolor spectrum. The results showed that JBS pseudocolor images can be used for caries detection and offer high sensitivity and specificity.
QUINTESSENCE INTERNATIONAL
(2023)
Review
Chemistry, Multidisciplinary
Alicia Almudever-Garcia, Leopoldo Forner, Jose Luis Sanz, Carmen Llena, Francisco Javier Rodriguez-Lozano, Julia Guerrero-Girones, Maria Melo
Summary: This systematic review highlights the potential application of pulse oximetry in diagnosing pulp vitality. While showing good sensitivity and specificity, its clinical use in dentistry is hindered by limitations such as the lack of a specific pulse oximeter for dental practice and insufficient evidence on the impact of different systemic and oral pathologies on pulp oxygen saturation levels.
APPLIED SCIENCES-BASEL
(2021)
Article
Dentistry, Oral Surgery & Medicine
F. J. Rodriguez-Lozano, A. Lozano, S. Lopez-Garcia, D. Garcia-Bernal, J. L. Sanz, J. Guerrero-Girones, C. Llena, L. Forner, M. Melo
Summary: The new tantalum oxide (Ta2O5)-containing material, NeoMTA 2, exhibited higher calcium release compared to other materials. All groups showed similar effects on hDPSC viability and migration, with substantial cell attachment and spreading. NeoMTA 2 upregulated osteo/odontogenic gene expression and promoted higher ROS production in hDPSCs, indicating its potential for vital pulp therapy.
CLINICAL ORAL INVESTIGATIONS
(2022)
Review
Dentistry, Oral Surgery & Medicine
Jose Luis Sanz, Julia Guerrero-Girones, Maria P. Pecci-Lloret, Miguel R. Pecci-Lloret, Maria Melo
Summary: This study aimed to qualitatively synthesize available in vitro studies assessing the biological interaction of PDLSCs and calcium silicate-based biomaterials. The findings suggest that calcium silicate-based endodontic materials exhibit adequate cytocompatibility and promote the osteo/cementogenic differentiation and mineralization potential of PDLSCs. Further research is needed to explore the impact of compositional differences, additives, sample preparation, and environmental conditions on the biological properties of these materials.
INTERNATIONAL ENDODONTIC JOURNAL
(2021)
Article
Environmental Sciences
Maria D. Ferrer, Salvadora Perez, Aranzazu Lopez Lopez, Jose Luis Sanz, Maria Melo, Carmen Llena, Alejandro Mira
Summary: The study evaluated various markers related to dental caries in adults and found lactate in plaque to be associated with caries, while tooth-brushing frequency was related to levels of Streptococcus dentisani. Women showed better oral health parameters than men, and low pH and high lactate levels were associated with high caries rates. No association was found between bacteria levels and caries indices.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Multidisciplinary Sciences
Maria Melo, Fadi Ata-Ali, Javier Ata-Ali, Jose Maria Martinez Gonzalez, Teresa Cobo
Summary: This study aims to determine the validity of two methods based on mineralisation of the third molar to predict the legal age of majority in a Spanish population. The results show that both the Demirjian method and the Cameriere method can be used with high reliability to determine the actual age of individuals, with a high predictive accuracy for the legal age of majority.
SCIENTIFIC REPORTS
(2022)
Article
Environmental Sciences
Triana Moreno, Jose Luis Sanz, Maria Melo, Carmen Llena
Summary: The study evaluated the tendency for overdiagnosis and overtreatment among last-year dentistry students at Valencia University in different clinical situations. Findings revealed students' inclination towards overtreatment of caries, inadequate selection of treatment for pulp pathology, and unnecessary treatment in medically compromised patients.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Rafael del Castillo, Javier Ata-Ali
Summary: This study reviewed the clinical use of nitride-coated titanium CAD/CAM implant abutments in the maxillary esthetic zone and highlighted the advantages compared to other materials. Nitride-coated titanium abutments were found to have optimal biocompatibility, mechanical characteristics, optical properties, and esthetic integration with soft tissues.
JOURNAL OF ESTHETIC AND RESTORATIVE DENTISTRY
(2023)
Review
Chemistry, Physical
Israa Ashkar, Jose Luis Sanz, Leopoldo Forner, Maria Melo
Summary: The aim of this systematic review was to evaluate and compare the penetration of calcium silicate-based sealers into dentinal tubules using in vitro studies. A total of 12 eligible studies were identified from a preliminary search of multiple databases. The most commonly used method to assess sealer penetration was the use of fluorochrome and confocal laser microscopy. Calcium silicate-based sealers showed favorable dentinal tubule penetration, although factors such as irrigation protocol, sealer activation, filling method, and root canal morphology could impact the results. EndoSequence BC Sealer demonstrated the highest penetration among the tested sealers. Further research on the influence of different fluorochromes in dentinal tubule penetration studies is needed. The limitations of the included in vitro studies restrict the applicability of the findings to clinical settings. Prospero registration: CRD42022383896.
Review
Medicine, General & Internal
Amaya Iturralde-Garrote, Jose Luis Sanz, Leopoldo Forner, Maria Melo, Clara Puig-Herreros
Summary: This article systematically reviewed the available studies on the volumetric characteristics of paranasal sinuses and their changes with age. The results showed that the volume of the maxillary and ethmoidal sinuses decreases with age, while the findings on the frontal and sphenoidal sinuses were inconclusive. Therefore, further evidence is needed to determine the volumetric changes of the frontal and sphenoidal sinuses.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
James Ghilotti, Iciar Fernandez, Jose Luis Sanz, Maria Melo, Carmen Llena
Summary: The aim of this in vitro study was to evaluate the remineralizing ability of three glass ionomers on demineralized dentin with different thicknesses and time periods. The results showed that all materials induced remineralization, with Riva Light Cure showing the most homogeneous results at all depths at 28 days. Equia Forte achieved the greatest effect at 2 mm and Ketac Molar at 1 mm. In terms of Ca/P ratio, Equia Forte and Riva Light Cure remineralized best at 2 mm, whereas for Ketac Molar, it was 1 mm. Carbonate apatite formation was higher at 24 h and 7 days for Ketac Molar, whereas it decreased at 14 days for Ketac Molar and peaked in Riva Light Cure and Equia Forte.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pediatrics
Eleonor Maria Velez Leon, Alberto Albaladejo Martinez, Monica Alejandra Preciado Sarmiento, Maria Augusta Cordero Lopez, Ana del Carmen Armas, Liliana Soledad Encalada Verdugo, Maria Melo
Summary: Dental caries is a major problem in preschool children and has a significant impact on their quality of life. This study evaluated 600 children aged 3 to 5 years and found a high prevalence of caries. The second molar was the most affected tooth, and a high treatment need was observed in the population.
Article
Dentistry, Oral Surgery & Medicine
Julia Guerrero-Girones, Sara Dudek, Gonzalo Llambes, Maria Melo, Carmen Llena
Summary: This study aimed to evaluate the effectiveness of five whitening toothpastes applied three times a day. The results showed that there were no significant differences in color and brightness after the treatment period and 1 week after the end of treatment, with Enawhite 2.0 and Whitekin showing relatively better results.
AMERICAN JOURNAL OF DENTISTRY
(2022)
Article
Medicine, General & Internal
Adriana Gonzalez-Saez, Laura Antonio-Zancajo, Javier Montero, Alberto Albaladejo, Maria Melo, Daniele Garcovich, Alfonso Alvarado-Lorenzo
Summary: The study found that friction in bracket type influences patients' perception of pain and oral health-related quality of life, with self-ligating brackets showing the least impact on patients.
MEDICINA-LITHUANIA
(2021)
Article
Dentistry, Oral Surgery & Medicine
Carmen Llena, Miriam Hernandez, Maria Melo, Jose Luis Sanz, Leopoldo Forner
Summary: The study showed that the success rate of indirect pulp capping was significantly higher than direct pulp capping, especially when caries were located in teeth unaffected by Molar Incisor Hypomineralization (MIH). However, there was no significant difference in success rates between the two methods when caries were present in teeth affected by MIH.
CLINICAL AND EXPERIMENTAL DENTAL RESEARCH
(2021)