Article
Chemistry, Multidisciplinary
Guillaume Schweicher, Guangfeng Liu, Pierre Fastre, Roland Resel, Mamatimin Abbas, Guillaume Wantz, Yves Henri Geerts
Summary: Directional crystallization based on temperature gradient approach was used as a post-deposition process to control the crystalline morphology of thin films. The treatment improved the roughness and crystalline order of the thin films, leading to flat and rather uniform films. Varying processing parameters helped correlate the conditions with thin film morphology improvements.
MATERIALS CHEMISTRY FRONTIERS
(2021)
Article
Cell Biology
Thomas Quast, Karolin Zoelzer, Donald Guu, Luis Alvarez, Carsten Kuesters, Eva Kiermaier, U. Benjamin Kaupp, Waldemar Kolanus
Summary: This study used a combination of microfluidics and quantitative in vitro live cell imaging to investigate the chemotactic sensing strategy of dendritic cells (DCs). The results showed that spatial sensing mechanisms are essential for the persistent chemotaxis of DCs in stable gradients.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Thermodynamics
Peng Zhang, Xueping Chen, Shuaijun Li, Qingbai Wu, Zhengdong Xu
Summary: The study investigates the formation and dissociation behaviors of methane hydrate under non uniform temperature fields, revealing the impact of water migration and heat transfer on hydrate distribution and saturation. Deformation phenomenon occurred in the medium during dissociation process, with gas flow from bottom to top making the dehydration process easier in higher temperature regions.
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
(2021)
Article
Engineering, Geological
Chao Zhang, Zijun Feng, Chen Mi, Zhengnan Chen
Summary: The study proposes the use of high-temperature thermal shock to induce directional cracking in hard rocks like granite, providing a solution to the issue of hard roofs that do not collapse properly during coal mining. Experimental results show that thermal shock can cause cracks in granite when heated to 500-550 degrees C at a heating rate of 114 degrees C/min. The findings also highlight the importance of horizontal stress difference in determining the location of cracks induced by thermal shock.
ROCK MECHANICS AND ROCK ENGINEERING
(2023)
Article
Thermodynamics
Peng Peng
Summary: This study analyzed liquid migration phenomena under both axial and radial temperature gradients, using a diffusion-controlled analytical model. The results showed that the morphology change of liquid droplets during their migration is mainly attributed to the conglomeration due to solute enrichment at the solid-liquid interface.
INTERNATIONAL JOURNAL OF THERMAL SCIENCES
(2021)
Article
Nanoscience & Nanotechnology
Xiaolong Ma, Matthew Olszta, Jia Liu, Miao Song, Mayur Pole, Madhusudhan R. Pallaka, Joshua Silverstein, Julian Escobar, Arun J. Bhattacharjee, Sundeep Mukherjee, Arun Devaraj, Bharat Gwalani
Summary: This report investigates the temperature effect on forming gradient structure in an Al-Si alloy during surface severe deformation. The results show that the intermediate temperature (473 K) produces the steepest gradient structure with anomalous hardening, which is attributed to the presence of profuse aluminum oxide particles in the top layer. The counterintuitive enhancement of strengthening at the intermediate temperature is explained by the interplay between thermal-driven, mechanical-aided oxidation and the wear-induced loss of surface materials.
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2022)
Article
Energy & Fuels
Yingmei Wang, Jie Liu, Wenze Jiao, Yadong Teng, Jing Zhan, Peng Zhang
Summary: To understand the impact of geothermal gradient on hydrate distribution, the Archie formula was used to calculate hydrate saturation. By adjusting parameters, the model's precision was enhanced under varying temperature gradient conditions. Methane hydrates were formed under different temperature gradients, and the values of porosity index and saturation index were fitted accordingly. The results showed that the temperature gradient had a complex influence on the values of the indices, with one decreasing gradually and the other fluctuating.
Article
Mechanics
Armagan Karamanli
Summary: In this study, the modified strain gradient elasticity theory is utilized to examine the transient vibrations of multi-directional functionally graded square microplates subjected to a moving concentrated load. A normal and shear deformable plate theory with five unknowns and Newmark's method are employed for the first time. The effects of analysis parameters on the dynamic amplification factors and time history analysis of strain gradient multi-directional functionally graded square microplates are investigated.
COMPOSITE STRUCTURES
(2023)
Article
Mechanics
F. dell'Isola, V. A. Eremeyev, V. A. Korolenko, Y. O. Solyaev
Summary: This article investigates the deformation of an initially spherical elastic body, considering the influence of the gradient of displacements on the deformation energy. By applying radial dead loads along the equator of the sphere, the analysis focuses on a specific case of second gradient continua. Unlike in first gradient continua, it is shown that these forces do not cause infinite displacement, but instead, the displacements are finite, as demonstrated using a series method for the boundary-value problem. Therefore, there is no formation of an edge at the material points where the forces are applied in the deformed configuration.
EUROPEAN JOURNAL OF MECHANICS A-SOLIDS
(2024)
Article
Dentistry, Oral Surgery & Medicine
Junya Yamashita, Akira Kimoto, Shun Teraoka, Yujiro Hiraoka, Daisuke Takeda, Yasumasa Kakei, Manabu Shigeoka, Takumi Hasegawa, Masaya Akashi
Summary: The study found that verteporfin photodynamic therapy (VP PDT) has the potential to be an additional treatment for large-sized ameloblastoma. Verteporfin targets low-density lipoprotein receptor (LDLR) and Yes-associated protein (YAP) to exert cytotoxic effects in human ameloblastoma tissues and cells. The combination of low-concentration verteporfin administration and laser irradiation had comparable efficacy to high-concentration verteporfin administration, and accelerated apoptotic bleb formation.
Article
Mechanics
Ramkarn Patne, Yehuda Agnon, Alexander Oron
Summary: The elasticity of the liquid plays a major role in determining the dominant mode of instability, with the horizontal component (HTG) of the oblique temperature gradient (OTG) showing strong stabilization effect on elastic modes in low liquid elasticity cases. However, if the liquid elasticity is sufficiently large, HTG fails to stabilize the upstream elastic mode. Liquid elasticity also stabilizes the Newtonian interaction mode and introduces a new elastic mode through thermocapillary flow introduced by HTG.
Article
Multidisciplinary Sciences
Toru Satoh, Takanobu Yagi, Yoichi Sawada, Kenji Sugiu, Yu Sato, Isao Date
Summary: This study found that bleb formation in unruptured intracranial aneurysms is associated with the establishment of peri-aneurysmal contact, which may have a greater impact on bleb formation than hemodynamics.
SCIENTIFIC REPORTS
(2022)
Article
Biodiversity Conservation
Yuting Jin, Junxia Li, Xueping Bai, Ying Zhao, Di Cui, Zhenju Chen
Summary: The proportion of latewood to earlywood in Larix gmelinii is influenced by both age and environment, with temperature having a significant impact on PLE changes over 100 years of tree age. The study suggests that rising temperatures may lead to abnormal radial growth in Larix gmelinii, potentially causing significant changes in the structure and function of boreal forests in cold temperate zones.
GLOBAL ECOLOGY AND CONSERVATION
(2021)
Article
Mathematics
Sergey M. Frolov, Vladislav S. Ivanov, Fedor S. Frolov, Pavel A. Vlasov, Richard Axelbaum, Phillip H. Irace, Grigoriy Yablonsky, Kendyl Waddell
Summary: This article presents the results of the joint American-Russian space experiment conducted on the International Space Station, which aimed to study the mechanisms of soot formation in a spherical diffusion flame under microgravity conditions. The study found that soot formation was mainly concentrated in the region where the local C/O atomic ratio was between 0.32 and 0.44, and the local temperature was greater than 1300-1500 K.
Article
Chemistry, Physical
Xiaohua Zhang, Yaping Zhao, Aitor Bergara, Guochun Yang
Summary: This study utilized swarm-intelligence structural search to discover a Li10Se electride compound that exhibits superconductivity under high pressure. The compound demonstrates a high superconducting transition temperature and provides a reference for realizing other superconducting electrides at lower pressures.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Review
Biophysics
Kotaro Oyama, Shuya Ishii, Madoka Suzuki
Summary: This review introduces recent opto-thermal technologies for microscopic analyses of cellular temperature-sensing systems, including optical microheating technologies and luminescent thermometers. The insights gained from these technologies have revealed various cellular responses to spatial and temporal changes in temperature, as well as the impact of short-term heating on cellular functions. The future prospects for opto-thermal manipulation of cellular functions and its contribution to understanding the mechanisms of cellular temperature-sensing systems are also discussed.
BIOPHYSICAL REVIEWS
(2022)
Article
Polymer Science
Ahmed E. Swilem, Tomoko Gowa Oyama, Kotaro Oyama, Atsushi Kimura, Mitsumasa Taguchi
Summary: CMC/G hybrid hydrogels demonstrate excellent biocompatibility and mechanical properties, effectively reducing postoperative adhesion. It has the potential to serve as a novel barrier material.
POLYMER DEGRADATION AND STABILITY
(2022)
Article
Chemistry, Multidisciplinary
Ferdinandus, Madoka Suzuki, Cong Quang Vu, Yoshie Harada, Satya Ranjan Sarker, Shin'ichi Ishiwata, Tetsuya Kitaguchi, Satoshi Arai
Summary: Thermal engineering at the microscale presents a significant challenge for basic biological research and biomaterials development. Researchers have developed a nanoparticle that can generate heat spots within live cells and measure the temperature increment using fluorescence thermometry. The results demonstrate the effectiveness of a single heat spot in altering cellular functions.
Article
Multidisciplinary Sciences
Kotaro Oyama, Vadim Zeeb, Toshiko Yamazawa, Nagomi Kurebayashi, Fuyu Kobirumaki-Shimozawa, Takashi Murayama, Hideto Oyamada, Satoru Noguchi, Takayoshi Inoue, Yukiko U. Inoue, Ichizo Nishino, Yoshie Harada, Norio Fukuda, Shin'ichi Ishiwata, Madoka Suzuki
Summary: This study investigates the relationship between mutant Ryanodine receptor type 1 (RyR1) and malignant hyperthermia (MH) using an optically controlled local heat-pulse method. The results show that RyR1 mutants are more heat sensitive and induce intracellular calcium bursts through heat-induced calcium release (HICR). HICR is also observed in skeletal muscles. This study highlights the complexity of MH and the positive feedback of HICR in thermogenesis in MH patients.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Multidisciplinary Sciences
Ryota Sakamoto, Ziane Izri, Yuta Shimamoto, Makito Miyazaki, Yusuke T. Maeda
Summary: Cell migration in confined environments is crucial for various biological processes. This study investigates the physical determinants of actomyosin-based migration in confined environments using an in vitro migratory cell model. The results reveal the importance of the physical interaction between actomyosin networks and the cell membrane in generating a propulsive force for cell movement.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Physiology
Yoshitaka Tsuboi, Kotaro Oyama, Fuyu Kobirumaki-Shimozawa, Takashi Murayama, Nagomi Kurebayashi, Toshiaki Tachibana, Yoshinobu Manome, Emi Kikuchi, Satoru Noguchi, Takayoshi Inoue, Yukiko U. Inoue, Ichizo Nishino, Shuichi Mori, Ryosuke Ishida, Hiroyuki Kagechika, Madoka Suzuki, Norio Fukuda, Toshiko Yamazawa
Summary: The R2509C mutation in RYR1 causes dysfunctional calcium dynamics in a mutant-gene dose-dependent manner in skeletal muscles, leading to MH-like episodes in heterozygous mice and embryonic lethality in homozygous mice.
JOURNAL OF GENERAL PHYSIOLOGY
(2022)
Article
Pharmacology & Pharmacy
Atsushi Kimura, Tadashi Arai, Miho Ueno, Kotaro Oyama, Hao Yu, Shinichi Yamashita, Yudai Otome, Mitsumasa Taguchi
Summary: Nanoparticle-based drug delivery systems have been developed as effective imaging agents for pancreatic cancer. Peptides composed of histidine and glycine were synthesized and irradiated with gamma-rays to produce peptide nanogels. These nanogels exhibited smaller size, high formation yield, stability, and biodegradability, making them effective nano-imaging agents for intractable cancers such as pancreatic cancer.
Article
Physiology
Shuya Ishii, Kotaro Oyama, Fuyu Kobirumaki-Shimozawa, Tomohiro Nakanishi, Naoya Nakahara, Madoka Suzuki, Shin'ichi Ishiwata, Norio Fukuda
Summary: Ishii et al. study the microheating-induced sliding movements of reconstituted thin filaments and find that the temperature dependence of thin filament sliding is regulated by myosin and tropomyosin-troponin. They also discover that mammalian striated muscle can contract efficiently through complementary regulation of myosin and tropomyosin-troponin within the body temperature range.
JOURNAL OF GENERAL PHYSIOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Ikuo Kurisaki, Madoka Suzuki
Summary: Thermogenesis is a physiological process that releases heat from intracellular biochemical reactions. Recent experiments have shown that externally applied heat can change intracellular signaling, leading to global changes in cell morphology and signaling. This suggests that thermogenesis plays a crucial role in modulating biological functions across different spatial scales.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2023)
Article
Physics, Multidisciplinary
Ryota Sakamoto, Makito Miyazaki, Yusuke T. Maeda
Summary: This study reports the transition between different modes of cytoplasmic actomyosin networks: steady actin flow and periodic actin waves. The critical factors for this transition are contractility and actin polymerization rate. This study provides an integrative understanding of the distinct pattern formation of active gels confined in cell-sized spaces.
PHYSICAL REVIEW RESEARCH
(2023)
Meeting Abstract
Ophthalmology
Ralf Brinkmann, Xi Zhang, Leonie Hoffmann, Eric Seifert, Mario Mordmueler, Dirk Theisen-Kunde, Madoka Suzuki, Yoko Miura
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)