Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors
出版年份 2019 全文链接
标题
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-11-19
DOI
10.1038/s41467-019-13007-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
- (2019) Julian Grünewald et al. NATURE
- Analysis and minimization of cellular RNA editing by DNA adenine base editors
- (2019) Holly A. Rees et al. Science Advances
- Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis
- (2019) Changyang Zhou et al. NATURE
- Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements
- (2018) Michael Kosicki et al. NATURE BIOTECHNOLOGY
- Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
- (2018) Luke W Koblan et al. NATURE BIOTECHNOLOGY
- Optimized base editors enable efficient editing in cells, organoids and mice
- (2018) Maria Paz Zafra et al. NATURE BIOTECHNOLOGY
- p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells
- (2018) Robert J. Ihry et al. NATURE MEDICINE
- CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response
- (2018) Emma Haapaniemi et al. NATURE MEDICINE
- Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression
- (2018) Benjamin J. Schmiedel et al. CELL
- CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons
- (2017) Pierre Billon et al. MOLECULAR CELL
- Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
- (2017) Justin Eyquem et al. NATURE
- Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
- (2017) Nicole M. Gaudelli et al. NATURE
- Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions
- (2017) Y Bill Kim et al. NATURE BIOTECHNOLOGY
- CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations
- (2017) Cem Kuscu et al. NATURE METHODS
- Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells
- (2017) Waseem Qasim et al. Science Translational Medicine
- Structure and Engineering of Francisella novicida Cas9
- (2016) Hisato Hirano et al. CELL
- Multiplex Genome Editing to Generate Universal CAR T Cells Resistant to PD1 Inhibition
- (2016) Jiangtao Ren et al. CLINICAL CANCER RESEARCH
- Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases
- (2016) Mark J Osborn et al. MOLECULAR THERAPY
- Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
- (2016) Alexis C. Komor et al. NATURE
- Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
- (2015) Ayal Hendel et al. NATURE BIOTECHNOLOGY
- RNA mis-splicing in disease
- (2015) Marina M. Scotti et al. NATURE REVIEWS GENETICS
- Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes
- (2015) Dmitry E Andreev et al. GENOME BIOLOGY
- A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy
- (2014) B. Philip et al. BLOOD
- Vector Integration and Tumorigenesis
- (2014) Christof von Kalle et al. HUMAN GENE THERAPY
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Evidence of efficient stop codon readthrough in four mammalian genes
- (2014) Gary Loughran et al. NUCLEIC ACIDS RESEARCH
- Easy quantitative assessment of genome editing by sequence trace decomposition
- (2014) Eva K. Brinkman et al. NUCLEIC ACIDS RESEARCH
- Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
- (2013) F. Ann Ran et al. CELL
- The who's who of T-cell differentiation: Human memory T-cell subsets
- (2013) Yolanda D. Mahnke et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Extensive Degradation of RNA Precursors by the Exosome in Wild-Type Cells
- (2012) Rajani Kanth Gudipati et al. MOLECULAR CELL
- Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
- (2012) J. Ross Chapman et al. MOLECULAR CELL
- Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer
- (2012) Elena Provasi et al. NATURE MEDICINE
- B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
- (2011) J. N. Kochenderfer et al. BLOOD
- Mutation in the TCRα subunit constant gene (TRAC) leads to a human immunodeficiency disorder characterized by a lack of TCRαβ+ T cells
- (2011) Neil V. Morgan et al. JOURNAL OF CLINICAL INVESTIGATION
- A Pre-mRNA Degradation Pathway that Selectively Targets Intron-Containing Genes Requires the Nuclear Poly(A)-Binding Protein
- (2011) Caroline Lemieux et al. MOLECULAR CELL
- Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
- (2011) David L. Porter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Widespread Impact of Nonsense-Mediated mRNA Decay on the Yeast Intronome
- (2008) Shakir Sayani et al. MOLECULAR CELL
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started