Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer

LncRNA MIR22HG negatively regulates miR-141-3p to enhance DAPK1 expression and inhibits endometrial carcinoma cells proliferation

(2018) Zhili Cui et al.   BIOMEDICINE & PHARMACOTHERAPY

Adenylosuccinate lyase enhances aggressiveness of endometrial cancer by increasing killer cell lectin-like receptor C3 expression by fumarate

(2018) Haengki Park et al.   LABORATORY INVESTIGATION

Identification and Functional Characterization of Long Non-coding RNA MIR22HG as a Tumor Suppressor for Hepatocellular Carcinoma

(2018) Dong-Yan Zhang et al.   Theranostics

The Long Non-coding RNA lnc-31 Interacts with Rock1 mRNA and Mediates Its YB-1-Dependent Translation

(2018) Dacia Dimartino et al.   Cell Reports

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma

(2017) Xiuxing Wang et al.   NATURE NEUROSCIENCE

Global analysis of ribosome-associated noncoding RNAs unveils new modes of translational regulation

(2017) Jérémie Bazin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase

(2017) Natasha Emmanuel et al.   Cell Reports

PHD2 Targeting Overcomes Breast Cancer Cell Death upon Glucose Starvation in a PP2A/B55α-Mediated Manner

(2017) Giusy Di Conza et al.   Cell Reports

The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels

(2017) Gerta Hoxhaj et al.   Cell Reports

Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling

(2016) Pardeep Heir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

(2016) Marco Sciacovelli et al.   NATURE

An ID2-dependent mechanism for VHL inactivation in cancer

(2016) Sang Bae Lee et al.   NATURE

Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

(2016) Giampaolo Bianchini et al.   Nature Reviews Clinical Oncology

pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner

(2016) J. Guo et al.   SCIENCE

EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor

(2016) Mamoru Takada et al.   Oncotarget

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

(2016) Javier Rodriguez et al.   Cell Reports

AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo

(2016) Manon Domise et al.   Scientific Reports

MYC, Metabolism, and Cancer

(2015) Z. E. Stine et al.   Cancer Discovery

Development and Quantitative Evaluation of a High-Resolution Metabolomics Technology

(2014) Xiaojing Liu et al.   ANALYTICAL CHEMISTRY

Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase

(2014) X. Zheng et al.   GENES & DEVELOPMENT

Adenylosuccinate lyase deficiency

(2014) Agnieszka Jurecka et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Posttranscriptional Gene Regulation by Long Noncoding RNA

(2012) Je-Hyun Yoon et al.   JOURNAL OF MOLECULAR BIOLOGY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

An HPLC-Based Assay of Adenylosuccinate Lyase in Erythrocytes

(2011) Jörgen Bierau et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein

(2010) J Xiong et al.   ONCOGENE

Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase

(2009) Qing Zhang et al.   CANCER CELL

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY

Proteomics-based Identification of Novel Factor Inhibiting Hypoxia-inducible Factor (FIH) Substrates Indicates Widespread Asparaginyl Hydroxylation of Ankyrin Repeat Domain-containing Proteins

(2008) Matthew E. Cockman et al.   MOLECULAR & CELLULAR PROTEOMICS

Global Regulation of Nucleotide Biosynthetic Genes by c-Myc

(2008) Yen-Chun Liu et al.   PLoS One