A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease

Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing

(2018) Qi Sun et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A slow-cycling subpopulation of melanoma cells with highly invasive properties

(2017) M Perego et al.   ONCOGENE

Intratumor and Intertumor Heterogeneity in Melanoma

(2017) Tomasz M. Grzywa et al.   Translational Oncology

Prevalence of βIII-tubulin (TUBB3) expression in human normal tissues and cancers

(2017) Fermín Person et al.   TUMOR BIOLOGY

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Therapeutic implications of melanoma heterogeneity

(2016) Stephanie J. Hachey et al.   EXPERIMENTAL DERMATOLOGY

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation

(2016) C. K. Kaufman et al.   SCIENCE

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling

(2016) Makoto Takeo et al.   Cell Reports

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Disequilibrium of BMP2 Levels in the Breast Stem Cell Niche Launches Epithelial Transformation by Overamplifying BMPR1B Cell Response

(2015) Marion Chapellier et al.   Stem Cell Reports

Phenotype Switching in Melanoma: Implications for Progression and Therapy

(2015) Frederic Zhentao Li et al.   Frontiers in Oncology

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

Metalloproteinases in melanoma

(2014) Nives Moro et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

How, and from which cell sources, do nevi really develop?

(2014) James M. Grichnik et al.   EXPERIMENTAL DERMATOLOGY

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Coupling of the radiosensitivity of melanocyte stem cells to their dormancy during the hair cycle

(2014) Makiko Ueno et al.   Pigment Cell & Melanoma Research

Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

(2014) Judith Müller et al.   Nature Communications

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

CreERT2expression from within the c-Kit gene locus allows efficient inducible gene targeting in and ablation of mast cells

(2013) Klaus Heger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NFIB is a governor of epithelial–melanocyte stem cell behaviour in a shared niche

(2013) Chiung-Ying Chang et al.   NATURE

Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling

(2013) Wei Chin Chou et al.   NATURE MEDICINE

Interstitial cells of Cajal integrate excitatory and inhibitory neurotransmission with intestinal slow-wave activity

(2013) Sabine Klein et al.   Nature Communications

A Dual Role for SOX10 in the Maintenance of the Postnatal Melanocyte Lineage and the Differentiation of Melanocyte Stem Cell Progenitors

(2013) Melissa L. Harris et al.   PLoS Genetics

SOX10 Expression in Malignant Melanoma, Carcinoma, and Normal Tissues

(2013) Amr Mohamed et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Epigenomic Annotation of Enhancers Predicts Transcriptional Regulators of Human Neural Crest

(2012) Alvaro Rada-Iglesias et al.   Cell Stem Cell

Postnatal lineage mapping of follicular melanocytes with the Tyr::CreERT2transgene

(2012) Melissa L. Harris et al.   Pigment Cell & Melanoma Research

Extrafollicular Dermal Melanocyte Stem Cells and Melanoma

(2012) James D. Hoerter et al.   Stem Cells International

Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration

(2011) Piul Rabbani et al.   CELL

Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells

(2011) Shintaro Tanimura et al.   Cell Stem Cell

Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells

(2011) K. L. VanDussen et al.   DEVELOPMENT

Interferon-γ links ultraviolet radiation to melanomagenesis in mice

(2011) M. Raza Zaidi et al.   NATURE

Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation

(2011) Emi K. Nishimura   Pigment Cell & Melanoma Research

Dermis-derived stem cells: a source of epidermal melanocytes and melanoma?

(2011) Susan E. Zabierowski et al.   Pigment Cell & Melanoma Research

A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth

(2010) Alexander Roesch et al.   CELL

Human dermal stem cells differentiate into functional epidermal melanocytes

(2010) Ling Li et al.   JOURNAL OF CELL SCIENCE

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Cancer stem cells versus phenotype-switching in melanoma

(2010) Keith S. Hoek et al.   Pigment Cell & Melanoma Research

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

BrafV600E cooperates with Pten loss to induce metastatic melanoma

(2009) David Dankort et al.   NATURE GENETICS

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

(2009) S. Fre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Pten Deficiency in Melanocytes Results in Resistance to Hair Graying and Susceptibility to Carcinogen-Induced Melanomagenesis

(2008) T. Inoue-Narita et al.   CANCER RESEARCH

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE

Melanoma and the tumor microenvironment

(2008) Jessie Villanueva et al.   Current Oncology Reports