MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription–replication conflicts
出版年份 2019 全文链接
标题
MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription–replication conflicts
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-09-19
DOI
10.1038/s41467-019-12271-w
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- SIRF: Quantitative in situ analysis of protein interactions at DNA replication forks
- (2018) Sunetra Roy et al. JOURNAL OF CELL BIOLOGY
- MRN complex-dependent recruitment of ubiquitylated BLM helicase to DSBs negatively regulates DNA repair pathways
- (2018) Vivek Tripathi et al. Nature Communications
- Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations
- (2018) Sarah Cohen et al. Nature Communications
- Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes
- (2018) Hai Dang Nguyen et al. CANCER RESEARCH
- 20 Years of Mre11 Biology: No End in Sight
- (2018) Tanya T. Paull MOLECULAR CELL
- EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma
- (2018) Aparna Gorthi et al. NATURE
- DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells
- (2018) Yizhou Joseph He et al. NATURE
- Xrs2 and Tel1 Independently Contribute to MR-Mediated DNA Tethering and Replisome Stability
- (2018) Julyun Oh et al. Cell Reports
- Sae2/CtIP prevents R-loop accumulation in eukaryotic cells
- (2018) Nodar Makharashvili et al. eLife
- SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability
- (2017) Chenlin Song et al. GENES & DEVELOPMENT
- RNA-DNA hybrid (R-loop) immunoprecipitation mapping: an analytical workflow to evaluate inherent biases
- (2017) László Halász et al. GENOME RESEARCH
- RECQ-like helicases Sgs1 and BLM regulate R-loop–associated genome instability
- (2017) Emily Yun-Chia Chang et al. JOURNAL OF CELL BIOLOGY
- Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
- (2017) Hai Dang Nguyen et al. MOLECULAR CELL
- Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability
- (2017) Amandine Bonnet et al. MOLECULAR CELL
- Dormant origins and fork protection mechanisms rescue sister forks arrested by transcription
- (2017) Alessandra Brambati et al. NUCLEIC ACIDS RESEARCH
- Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis
- (2017) Xiaowen Zhang et al. Nature Communications
- MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells
- (2017) Delphine Lemaçon et al. Nature Communications
- The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage
- (2017) Juan Lafuente-Barquero et al. PLoS Genetics
- Replication Fork Protection Factors Controlling R-Loop Bypass and Suppression
- (2017) Emily Chang et al. Genes
- Transcription as a Threat to Genome Integrity
- (2016) Hélène Gaillard et al. Annual Review of Biochemistry
- Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair
- (2016) Corina Ohle et al. CELL
- Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes
- (2016) Nguyen Ngoc Hoa et al. MOLECULAR CELL
- Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals
- (2016) Lionel A. Sanz et al. MOLECULAR CELL
- RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together
- (2016) Andrew Seeber et al. MOLECULAR CELL
- Differential roles of the RNases H in preventing chromosome instability
- (2016) Anjali D. Zimmer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- p53 Maintains Genomic Stability by Preventing Interference between Transcription and Replication
- (2016) Constance Qiao Xin Yeo et al. Cell Reports
- A Checkpoint-Related Function of the MCM Replicative Helicase Is Required to Avert Accumulation of RNA:DNA Hybrids during S-phase and Ensuing DSBs during G2/M
- (2016) Sriram Vijayraghavan et al. PLoS Genetics
- Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinks
- (2016) Chen Ling et al. Cell Discovery
- Roles of human POLD1 and POLD3 in genome stability
- (2016) Emanuela Tumini et al. Scientific Reports
- Elevated Genome-Wide Instability in Yeast Mutants Lacking RNase H Activity
- (2015) K. O'Connell et al. GENETICS
- The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription
- (2015) Rebekka A. Schwab et al. MOLECULAR CELL
- BRCA1 Recruitment to Transcriptional Pause Sites Is Required for R-Loop-Driven DNA Damage Repair
- (2015) Elodie Hatchi et al. MOLECULAR CELL
- A flow cytometry–based method to simplify the analysis and quantification of protein association to chromatin in mammalian cells
- (2015) Josep V Forment et al. Nature Protocols
- The Fanconi Anemia Pathway Protects Genome Integrity from R-loops
- (2015) María L. García-Rubio et al. PLoS Genetics
- RECQL5 Controls Transcript Elongation and Suppresses Genome Instability Associated with Transcription Stress
- (2014) Marco Saponaro et al. CELL
- Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability
- (2014) Julie Sollier et al. MOLECULAR CELL
- BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2
- (2014) Vaibhav Bhatia et al. NATURE
- DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal
- (2014) Sébastien Britton et al. NUCLEIC ACIDS RESEARCH
- The Histone-Fold Protein CHRAC14 Influences Chromatin Composition in Response to DNA Damage
- (2014) Veena Mathew et al. Cell Reports
- The Essential Function of the MRN Complex in the Resolution of Endogenous Replication Intermediates
- (2014) Christopher Bruhn et al. Cell Reports
- Genome-Wide Profiling of Yeast DNA:RNA Hybrid Prone Sites with DRIP-Chip
- (2014) Yujia A. Chan et al. PLoS Genetics
- Balony: a software package for analysis of data generated by synthetic genetic array experiments
- (2013) Barry P Young et al. BMC BIOINFORMATICS
- Fanconi Anemia Group J Helicase and MRE11 Nuclease Interact To Facilitate the DNA Damage Response
- (2013) A. N. Suhasini et al. MOLECULAR AND CELLULAR BIOLOGY
- DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
- (2013) Atsushi Shibata et al. MOLECULAR CELL
- Replication stress links structural and numerical cancer chromosomal instability
- (2013) Rebecca A. Burrell et al. NATURE
- RNase H2 roles in genome integrity revealed by unlinking its activities
- (2013) Hyongi Chon et al. NUCLEIC ACIDS RESEARCH
- CHROMATRA: a Galaxy tool for visualizing genome-wide chromatin signatures
- (2012) T. Hentrich et al. BIOINFORMATICS
- Senataxin Associates with Replication Forks to Protect Fork Integrity across RNA-Polymerase-II-Transcribed Genes
- (2012) Amaya Alzu et al. CELL
- R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants
- (2012) P. C. Stirling et al. GENES & DEVELOPMENT
- Role of MRE11 in Cell Proliferation, Tumor Invasion, and DNA Repair in Breast Cancer
- (2012) Shyng-Shiou F. Yuan et al. JNCI-Journal of the National Cancer Institute
- Cohesin Association to Replication Sites Depends on Rad50 and Promotes Fork Restart
- (2012) Mireille Tittel-Elmer et al. MOLECULAR CELL
- Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11
- (2011) Katharina Schlacher et al. CELL
- Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles
- (2011) Belén Gómez-González et al. EMBO JOURNAL
- RNase H and Multiple RNA Biogenesis Factors Cooperate to Prevent RNA:DNA Hybrids from Generating Genome Instability
- (2011) Lamia Wahba et al. MOLECULAR CELL
- Yeast Sen1 Helicase Protects the Genome from Transcription-Associated Instability
- (2011) Hannah E. Mischo et al. MOLECULAR CELL
- Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination
- (2011) Konstantina Skourti-Stathaki et al. MOLECULAR CELL
- REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms
- (2011) Fran Supek et al. PLoS One
- Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis
- (2010) A. El Hage et al. GENES & DEVELOPMENT
- RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network
- (2010) Liyi Geng et al. JOURNAL OF CELL BIOLOGY
- WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase
- (2010) Prasun Chakraborty et al. NUCLEIC ACIDS RESEARCH
- The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress
- (2009) Mireille Tittel-Elmer et al. EMBO JOURNAL
- MRE11–RAD50–NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair
- (2009) Céline Roques et al. EMBO JOURNAL
- Ribonuclease H: the enzymes in eukaryotes
- (2009) Susana M. Cerritelli et al. FEBS Journal
- Synthetic Lethal Genetic Interactions That Decrease Somatic Cell Proliferation in Caenorhabditis elegans Identify the Alternative RFCCTF18 as a Candidate Cancer Drug Target
- (2009) Jessica McLellan et al. MOLECULAR BIOLOGY OF THE CELL
- A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability
- (2009) Renee D. Paulsen et al. MOLECULAR CELL
- FANCM Connects the Genome Instability Disorders Bloom's Syndrome and Fanconi Anemia
- (2009) Andrew J. Deans et al. MOLECULAR CELL
- Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription
- (2009) Sandie Tuduri et al. NATURE CELL BIOLOGY
- MRE11 complex links RECQ5 helicase to sites of DNA damage
- (2009) Lu Zheng et al. NUCLEIC ACIDS RESEARCH
- The Human RecQ Helicases, BLM and RECQ1, Display Distinct DNA Substrate Specificities
- (2008) Venkateswarlu Popuri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex
- (2008) Aude Dupré et al. Nature Chemical Biology
- Improved genome-wide localization by ChIP-chip using double-round T7 RNA polymerase-based amplification
- (2008) Harm van Bakel et al. NUCLEIC ACIDS RESEARCH
- Defining genetic interaction
- (2008) R. Mani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started