HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis
出版年份 2019 全文链接
标题
HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-10-08
DOI
10.1038/s41467-019-12163-z
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- An ELISA Assay for Quantifying Monomeric C-Reactive Protein in Plasma
- (2018) Lin Zhang et al. Frontiers in Immunology
- Monomeric C-Reactive Protein Binds and Neutralizes Receptor Activator of NF-κB Ligand-Induced Osteoclast Differentiation
- (2018) Zhe-Kun Jia et al. Frontiers in Immunology
- Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis
- (2018) Chao Liang et al. Nature Communications
- Anti-inflammatory effects in a mouse osteoarthritis model of a mixture of glucosamine and chitooligosaccharides produced by bi-enzyme single-step hydrolysis
- (2018) Yali Li et al. Scientific Reports
- Comparing phenotypic variation between inbred and outbred mice
- (2018) Alexander H. Tuttle et al. NATURE METHODS
- RANKL: A therapeutic target for bone destruction in rheumatoid arthritis
- (2017) Sakae Tanaka et al. Modern Rheumatology
- Precision Medicine in Rheumatoid Arthritis
- (2017) James Bluett et al. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
- Osteoclastic miR-214 targets TRAF3 to contribute to osteolytic bone metastasis of breast cancer
- (2017) Jin Liu et al. Scientific Reports
- Fluorescence assay of dihydroorotate dehydrogenase that may become a cancer biomarker
- (2017) Sheng Yin et al. Scientific Reports
- Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice
- (2016) Akari Suzuki et al. BMC MUSCULOSKELETAL DISORDERS
- Safety and Efficacy of Biological Disease-Modifying Antirheumatic Drugs in Older Rheumatoid Arthritis Patients: Staying the Distance
- (2016) Alla Ishchenko et al. DRUGS & AGING
- IL-6 pathway in the liver: From physiopathology to therapy
- (2016) Dirk Schmidt-Arras et al. JOURNAL OF HEPATOLOGY
- Effects of C-reactive protein on bone cells
- (2016) In-Jin Cho et al. LIFE SCIENCES
- A Truncated IL-17RC Peptide Ameliorates Synovitis and Bone Destruction of Arthritic Mice
- (2016) Yuxuan Du et al. Advanced Healthcare Materials
- C-reactive protein and inflammation: conformational changes affect function
- (2015) Yi Wu et al. BIOLOGICAL CHEMISTRY
- A delivery system specifically approaching bone resorption surfaces to facilitate therapeutic modulation of microRNAs in osteoclasts
- (2015) Jin Liu et al. BIOMATERIALS
- Norisoboldine, an Anti-Arthritis Alkaloid Isolated from Radix Linderae, Attenuates Osteoclast Differentiation and Inflammatory Bone Erosion in an Aryl Hydrocarbon Receptor-Dependent Manner
- (2015) Zhi-feng Wei et al. International Journal of Biological Sciences
- Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α
- (2015) Ivan D Mascanfroni et al. NATURE MEDICINE
- Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference–based bone anabolic strategy
- (2015) Chao Liang et al. NATURE MEDICINE
- Role of C-reactive protein in osteoclastogenesis in rheumatoid arthritis
- (2015) Kyoung-Woon Kim et al. ARTHRITIS RESEARCH & THERAPY
- Characterization of Toll-Like Receptor-4 (TLR-4) in the Spleen and Thymus of Swiss Albino Mice and Its Modulation in Experimental Endotoxemia
- (2015) Chandrayee Ghosh et al. Journal of Immunology Research
- Evidence Should Trump Intuition by Preferring Inbred Strains to Outbred Stocks in Preclinical Research
- (2014) M. F. W. Festing ILAR JOURNAL
- Unknown
- (2014) Markus Mandl et al. MOLECULAR MEDICINE
- AhR-Mediated, Non-Genomic Modulation of IDO1 Function
- (2014) Maria Teresa Pallotta et al. Frontiers in Immunology
- Several Classical Mouse Inbred Strains, Including DBA/2, NOD/Lt, FVB/N, and SJL/J, Carry a Putative Loss-of-Function Allele of Gpr84
- (2013) C. J. Perez et al. JOURNAL OF HEREDITY
- TNF-like Ligand 1A (TL1A) Gene Knockout Leads to Ameliorated Collagen-Induced Arthritis in Mice: Implication of TL1A in Humoral Immune Responses
- (2013) X. Wang et al. JOURNAL OF IMMUNOLOGY
- Structure and Dimerization Properties of the Aryl Hydrocarbon Receptor PAS-A Domain
- (2013) D. Wu et al. MOLECULAR AND CELLULAR BIOLOGY
- Distinctive Cytokines as Biomarkers Predicting Fatal Outcome of Severe Staphylococcus aureus Bacteremia in Mice
- (2013) Sanne van den Berg et al. PLoS One
- C57BL/6 mice need MHC class II Aq to develop collagen-induced arthritis dependent on autoreactive T cells
- (2012) Johan Bäcklund et al. ANNALS OF THE RHEUMATIC DISEASES
- A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy
- (2012) Ge Zhang et al. NATURE MEDICINE
- Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment
- (2012) Georg Schett et al. Nature Reviews Rheumatology
- Collagen-induced arthritis is exacerbated in C-reactive protein-deficient mice
- (2011) Nicholas R. Jones et al. ARTHRITIS AND RHEUMATISM
- Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice
- (2011) Bharath Nath et al. HEPATOLOGY
- The Pathogenesis of Rheumatoid Arthritis
- (2011) Iain B. McInnes et al. NEW ENGLAND JOURNAL OF MEDICINE
- Update on the use of conventional disease-modifying antirheumatic drugs in the management of rheumatoid arthritis
- (2010) Michael G Feely et al. CURRENT OPINION IN RHEUMATOLOGY
- No Reduction of Atherosclerosis in C-reactive Protein (CRP)-deficient Mice
- (2010) Daniel Teupser et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
- (2010) Akin Akinc et al. MOLECULAR THERAPY
- The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor
- (2010) Edmond F. O'Donnell et al. PLoS One
- Ah receptor represses acute-phase response gene expression without binding to its cognate response element
- (2009) Rushang D Patel et al. LABORATORY INVESTIGATION
- Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver
- (2009) Akin Akinc et al. MOLECULAR THERAPY
- Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization
- (2009) K. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Serum Levels of TRAP5b, a New Bone Resorption Marker Unaffected by Renal Dysfunction, as a Useful Marker of Cortical Bone Loss in Hemodialysis Patients
- (2008) Kaori Shidara et al. CALCIFIED TISSUE INTERNATIONAL
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
- (2008) Akin Akinc et al. NATURE BIOTECHNOLOGY
- LOOPER: a molecular mechanics-based algorithm for protein loop prediction
- (2008) V. Z. Spassov et al. PROTEIN ENGINEERING DESIGN & SELECTION
- The association of anti-CCP antibodies with disease activity in rheumatoid arthritis
- (2008) Münevver Serdaroğlu et al. RHEUMATOLOGY INTERNATIONAL
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