Molecular basis of PIP2-dependent regulation of the Ca2+-activated chloride channel TMEM16A
出版年份 2019 全文链接
标题
Molecular basis of PIP2-dependent regulation of the Ca2+-activated chloride channel TMEM16A
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-08-21
DOI
10.1038/s41467-019-11784-8
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Drosophila Subdued is a moonlighting transmembrane protein 16 (TMEM16) that transports ions and phospholipids
- (2019) Trieu Le et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An inner activation gate controls TMEM16F phospholipid scrambling
- (2019) Trieu Le et al. Nature Communications
- Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F
- (2019) Carolina Alvadia et al. eLife
- Phosphatidylinositol 4,5-bisphosphate, cholesterol, and fatty acids modulate the calcium-activated chloride channel TMEM16A (ANO1)
- (2018) José J. De Jesús-Pérez et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel
- (2018) Christian J. Peters et al. NEURON
- Bioinformatic characterization of the Anoctamin Superfamily of Ca2+-activated ion channels and lipid scramblases
- (2018) Arturo Medrano-Soto et al. PLoS One
- Phosphatidylinositol-(4, 5)-bisphosphate regulates calcium gating of small-conductance cation channel TMEM16F
- (2018) Wenlei Ye et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of the mechanosensitive OSCA channels
- (2018) Mingfeng Zhang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cryo-EM structure of the mechanically activated ion channel OSCA1.2
- (2018) Sebastian Jojoa-Cruz et al. eLife
- Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM
- (2017) Cristina Paulino et al. NATURE
- Cryo-EM structures of the TMEM16A calcium-activated chloride channel
- (2017) Shangyu Dang et al. NATURE
- Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A
- (2017) Cristina Paulino et al. eLife
- Independent activation of distinct pores in dimeric TMEM16A channels
- (2016) Grace Jeng et al. JOURNAL OF GENERAL PHYSIOLOGY
- Independent activation of ion conduction pores in the double-barreled calcium-activated chloride channel TMEM16A
- (2016) Novandy K. Lim et al. JOURNAL OF GENERAL PHYSIOLOGY
- CHARMM36m: an improved force field for folded and intrinsically disordered proteins
- (2016) Jing Huang et al. NATURE METHODS
- Phosphoinositide Control of Membrane Protein Function: A Frontier Led by Studies on Ion Channels
- (2015) Diomedes E. Logothetis et al. Annual Review of Physiology
- Lipid agonism: The PIP2 paradigm of ligand-gated ion channels
- (2015) Scott B. Hansen BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Phosphoinositides regulate ion channels
- (2015) Bertil Hille et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field
- (2015) Jumin Lee et al. Journal of Chemical Theory and Computation
- Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels
- (2015) Christian J. Peters et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibitory role of phosphatidylinositol 4,5-bisphosphate on TMEM16A-encoded calcium-activated chloride channels in rat pulmonary artery
- (2014) H A T Pritchard et al. BRITISH JOURNAL OF PHARMACOLOGY
- Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin
- (2014) Kuai Yu et al. JOURNAL OF GENERAL PHYSIOLOGY
- Calcium-calmodulin does not alter the anion permeability of the mouse TMEM16A calcium-activated chloride channel
- (2014) Yawei Yu et al. JOURNAL OF GENERAL PHYSIOLOGY
- Preferred Orientations of Phosphoinositides in Bilayers and Their Implications in Protein Recognition Mechanisms
- (2014) Emilia L. Wu et al. JOURNAL OF PHYSICAL CHEMISTRY B
- X-ray structure of a calcium-activated TMEM16 lipid scramblase
- (2014) Janine D. Brunner et al. NATURE
- OSCA1 mediates osmotic-stress-evoked Ca2+ increases vital for osmosensing in Arabidopsis
- (2014) Fang Yuan et al. NATURE
- Structure and Function of TMEM16 Proteins (Anoctamins)
- (2014) Nicoletta Pedemonte et al. PHYSIOLOGICAL REVIEWS
- Activation and Inhibition of TMEM16A Calcium-Activated Chloride Channels
- (2014) Yu-Li Ni et al. PLoS One
- Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl−channels
- (2014) Tingting Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity
- (2014) Jason Tien et al. eLife
- Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald
- (2013) Romelia Salomon-Ferrer et al. Journal of Chemical Theory and Computation
- Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels
- (2013) H. Terashima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation
- (2012) Huanghe Yang et al. CELL
- Explaining Calcium-Dependent Gating of Anoctamin-1 Chloride Channels Requires a Revised Topology
- (2012) Kuai Yu et al. CIRCULATION RESEARCH
- Dynamic modulation of ANO1/TMEM16A HCO3- permeability by Ca2+/calmodulin
- (2012) J. Jung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal Structure of the Mammalian GIRK2 K+ Channel and Gating Regulation by G Proteins, PIP2, and Sodium
- (2011) Matthew R. Whorton et al. CELL
- Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2
- (2011) Scott B. Hansen et al. NATURE
- KCNE1 enhances phosphatidylinositol 4,5-bisphosphate (PIP2) sensitivity of IKs to modulate channel activity
- (2011) Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop
- (2011) Q. Xiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Calmodulin-dependent activation of the epithelial calcium-dependent chloride channel TMEM16A
- (2010) Yuemin Tian et al. FASEB JOURNAL
- Tmem16AEncodes the Ca2+-activated Cl−Channel in Mouse Submandibular Salivary Gland Acinar Cells
- (2010) Victor G. Romanenko et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types
- (2010) Jeffery B. Klauda et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Calcium-dependent phospholipid scrambling by TMEM16F
- (2010) Jun Suzuki et al. NATURE
- PIP2 Is a Necessary Cofactor for Ion Channel Function: How and Why?
- (2008) Byung-Chang Suh et al. Annual Review of Biophysics
- Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit
- (2008) Björn Christian Schroeder et al. CELL
- TMEM16A confers receptor-activated calcium-dependent chloride conductance
- (2008) Young Duk Yang et al. NATURE
- TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity
- (2008) A. Caputo et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now