Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain

Arkadia (RING Finger Protein 111) Mediates Sumoylation-Dependent Stabilization of Nrf2 Through K48-Linked Ubiquitination

(2018) Deneshia J. McIntosh et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A short conserved motif in ALYREF directs cap- and EJC-dependent assembly of export complexes on spliced mRNAs

(2016) Agnieszka M. Gromadzka et al.   NUCLEIC ACIDS RESEARCH

SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair

(2015) Loes van Cuijk et al.   Nature Communications

Structural analysis of poly-SUMO chain recognition by the RNF4-SIMs domain

(2014) Camy C.-H. Kung et al.   BIOCHEMICAL JOURNAL

Multiple Arkadia/RNF111 Structures Coordinate Its Polycomb Body Association and Transcriptional Control

(2014) Huaiyu Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis

(2014) Julie Schou et al.   PLoS One

Structural insight into SUMO chain recognition and manipulation by the ubiquitin ligase RNF4

(2014) Yingqi Xu et al.   Nature Communications

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

Multivalent interactions of the SUMO-interaction motifs in RING finger protein 4 determine the specificity for chains of the SUMO

(2013) Kirstin Keusekotten et al.   BIOCHEMICAL JOURNAL

Decoding the SUMO signal

(2013) Ronald T. Hay   BIOCHEMICAL SOCIETY TRANSACTIONS

SUMO-targeted ubiquitin ligases

(2013) Annie M. Sriramachandran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Expanding SUMO and ubiquitin-mediated signaling through hybrid SUMO-ubiquitin chains and their receptors

(2013) Catherine M. Guzzo et al.   CELL CYCLE

SUMO: A Multifaceted Modifier of Chromatin Structure and Function

(2013) Caelin Cubeñas-Potts et al.   DEVELOPMENTAL CELL

RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

(2013) Sara L. Poulsen et al.   JOURNAL OF CELL BIOLOGY

PML isoforms in response to arsenic: high-resolution analysis of PML body structure and degradation

(2013) K. J. Hands et al.   JOURNAL OF CELL SCIENCE

Arkadia, a Novel SUMO-Targeted Ubiquitin Ligase Involved in PML Degradation

(2013) Y. Erker et al.   MOLECULAR AND CELLULAR BIOLOGY

Rnf165/Ark2C Enhances BMP-Smad Signaling to Mediate Motor Axon Extension

(2013) Claire E. Kelly et al.   PLOS BIOLOGY

A Novel SUMO1-specific Interacting Motif in Dipeptidyl Peptidase 9 (DPP9) That Is Important for Enzymatic Regulation

(2012) Esther Pilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Poly-Small Ubiquitin-like Modifier (PolySUMO)-binding Proteins Identified through a String Search

(2012) Huaiyu Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recognition and Cleavage of Related to Ubiquitin 1 (Rub1) and Rub1-Ubiquitin Chains by Components of the Ubiquitin-Proteasome System

(2012) Rajesh K. Singh et al.   MOLECULAR & CELLULAR PROTEOMICS

RNF4-Dependent Hybrid SUMO-Ubiquitin Chains Are Signals for RAP80 and Thereby Mediate the Recruitment of BRCA1 to Sites of DNA Damage

(2012) C. M. Guzzo et al.   Science Signaling

SUMO playing tag with ubiquitin

(2011) Gerrit J.K. Praefcke et al.   TRENDS IN BIOCHEMICAL SCIENCES

Three-dimensional organization of promyelocytic leukemia nuclear bodies

(2010) M. Lang et al.   JOURNAL OF CELL SCIENCE

SUMO Chain Formation Is Required for Response to Replication Arrest in S. pombe

(2009) Andrew Skilton et al.   PLoS One

System-Wide Changes to SUMO Modifications in Response to Heat Shock

(2009) F. Golebiowski et al.   Science Signaling

Regulation of TGF-β family signaling by E3 ubiquitin ligases

(2008) Yasumichi Inoue et al.   CANCER SCIENCE

Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML

(2008) Stefan R. Weisshaar et al.   FEBS LETTERS

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY