Loss of ubiquitin-conjugating enzyme E2 (Ubc9) in macrophages exacerbates multiple low-dose streptozotocin-induced diabetes by attenuating M2 macrophage polarization
出版年份 2019 全文链接
标题
Loss of ubiquitin-conjugating enzyme E2 (Ubc9) in macrophages exacerbates multiple low-dose streptozotocin-induced diabetes by attenuating M2 macrophage polarization
作者
关键词
-
出版物
Cell Death & Disease
Volume 10, Issue 12, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-11-26
DOI
10.1038/s41419-019-2130-z
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Both conditional ablation and overexpression of E2 SUMO-conjugating enzyme (UBC9) in mouse pancreatic beta cells result in impaired beta cell function
- (2018) Xiaoyu He et al. DIABETOLOGIA
- SUMO-defective c-Maf preferentially transactivates Il21 to exacerbate autoimmune diabetes
- (2018) Chao-Yuan Hsu et al. JOURNAL OF CLINICAL INVESTIGATION
- SUMO-mediated regulation of NLRP3 modulates inflammasome activity
- (2018) Rachael Barry et al. Nature Communications
- IL-33 Prevents MLD-STZ Induction of Diabetes and Attenuate Insulitis in Prediabetic NOD Mice
- (2018) Sladjana Pavlovic et al. Frontiers in Immunology
- Role of small ubiquitin-like modifier proteins-1 (SUMO-1) in regulating migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis
- (2018) Minxi Lao et al. EXPERIMENTAL CELL RESEARCH
- Gain-of-function mutant p53 activates small GTPase Rac1 through SUMOylation to promote tumor progression
- (2017) Xuetian Yue et al. GENES & DEVELOPMENT
- Taenia crassiceps Antigens Control Experimental Type 1 Diabetes by Inducing Alternatively Activated Macrophages
- (2017) Arlett Espinoza-Jiménez et al. MEDIATORS OF INFLAMMATION
- Aloperine Protects Mice against DSS-Induced Colitis by PP2A-Mediated PI3K/Akt/mTOR Signaling Suppression
- (2017) Xiaoxia Fu et al. MEDIATORS OF INFLAMMATION
- Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice
- (2017) Javier A. Carrero et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial DNA Activates the NLRP3 Inflammasome and Predisposes to Type 1 Diabetes in Murine Model
- (2017) Daniela Carlos et al. Frontiers in Immunology
- Macrophage fatty acid oxidation and its roles in macrophage polarization and fatty acid-induced inflammation
- (2016) Dmitry Namgaladze et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Loss of Mbd2 Protects Mice Against High-Fat Diet–Induced Obesity and Insulin Resistance by Regulating the Homeostasis of Energy Storage and Expenditure
- (2016) Jia Cheng et al. DIABETES
- Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation
- (2016) Stanley Ching-Cheng Huang et al. IMMUNITY
- Fatty acid oxidation in macrophage polarization
- (2016) Mitsunori Nomura et al. NATURE IMMUNOLOGY
- High mobility group box 1 skews macrophage polarization and negatively influences phagocytosis of apoptotic cells
- (2016) Fleur Schaper et al. RHEUMATOLOGY
- SENP1 regulates IFN-γ−STAT1 signaling through STAT3−SOCS3 negative feedback loop
- (2016) Tingting Yu et al. Journal of Molecular Cell Biology
- Protein SUMOylation Is Required for Regulatory T Cell Expansion and Function
- (2016) Xiao Ding et al. Cell Reports
- Macrophages: Development and Tissue Specialization
- (2015) Chen Varol et al. Annual Review of Immunology
- Macrophage dynamics are regulated by local macrophage proliferation and monocyte recruitment in injured pancreas
- (2015) Naomi Van Gassen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mast cells control insulitis and increase Treg cells to confer protection against STZ-induced type 1 diabetes in mice
- (2015) Daniela Carlos et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Tissue-resident macrophages: then and now
- (2015) Luke C. Davies et al. IMMUNOLOGY
- The pancreas anatomy conditions the origin and properties of resident macrophages
- (2015) Boris Calderon et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Reshaping of Human Macrophage Polarization through Modulation of Glucose Catabolic Pathways
- (2015) Elena Izquierdo et al. JOURNAL OF IMMUNOLOGY
- Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing
- (2015) Adrien Decque et al. NATURE IMMUNOLOGY
- Chop deficiency prevents UUO-induced renal fibrosis by attenuating fibrotic signals originated from Hmgb1/TLR4/NFκB/IL-1β signaling
- (2015) M Zhang et al. Cell Death & Disease
- A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress
- (2015) Joan Ritho et al. Cell Reports
- Concise Review: Macrophages: Versatile Gatekeepers During Pancreatic β-Cell Development, Injury, and Regeneration
- (2015) Naomi Van Gassen et al. Stem Cells Translational Medicine
- Loss of NADPH Oxidase–Derived Superoxide Skews Macrophage Phenotypes to Delay Type 1 Diabetes
- (2014) Lindsey E. Padgett et al. DIABETES
- Cellular Metabolism and Macrophage Functional Polarization
- (2014) Linnan Zhu et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- MBD2 regulates TH17 differentiation and experimental autoimmune encephalomyelitis by controlling the homeostasis of T-bet/Hlx axis
- (2014) Jixin Zhong et al. JOURNAL OF AUTOIMMUNITY
- Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice
- (2012) R. Parsa et al. DIABETES
- The Small Ubiquitin-like Modifier-Deconjugating Enzyme Sentrin-Specific Peptidase 1 Switches IFN Regulatory Factor 8 from a Repressor to an Activator during Macrophage Activation
- (2012) T.-H. Chang et al. JOURNAL OF IMMUNOLOGY
- SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFN
- (2011) A. Begitt et al. BLOOD
- Loss of Methyl-CpG–Binding Domain Protein 2 Enhances Endothelial Angiogenesis and Protects Mice Against Hind-Limb Ischemic Injury
- (2011) Xiaoquan Rao et al. CIRCULATION
- SUMOylation of the GTPase Rac1 is required for optimal cell migration
- (2010) Sonia Castillo-Lluva et al. NATURE CELL BIOLOGY
- The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
- (2010) Takashi Satoh et al. NATURE IMMUNOLOGY
- The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
- (2010) Jaclyn R. Gareau et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Defective Phagocytosis of Apoptotic Cells by Macrophages in Atherosclerotic Lesions of ob/ob Mice and Reversal by a Fish Oil Diet
- (2009) Suzhao Li et al. CIRCULATION RESEARCH
- Extracellular High-Mobility Group Box 1 Acts as an Innate Immune Mediator to Enhance Autoimmune Progression and Diabetes Onset in NOD Mice
- (2008) J. Han et al. DIABETES
- SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-δ
- (2008) Yumiko Oishi et al. NATURE MEDICINE
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