Oligonucleotide quantification and metabolite profiling by high-resolution and accurate mass spectrometry

Improved LC/MS Methods for the Analysis of Metal-Sensitive Analytes Using Medronic Acid as a Mobile Phase Additive

(2018) Jordy J. Hsiao et al.   ANALYTICAL CHEMISTRY

Reversal of siRNA-mediated gene silencing in vivo

(2018) Ivan Zlatev et al.   NATURE BIOTECHNOLOGY

Development of SPE method for the extraction of phosphorothioate oligonucleotides from serum samples

(2018) Łukasz Nuckowski et al.   Bioanalysis

Quantitative determination of AVI-7100 (Radavirsen), a phosphorodiamidate morpholino oligomer (PMOplus® ), in human plasma using LC–MS/MS

(2017) Min Meng et al.   Bioanalysis

Quantitative determination of a siRNA (AD00370) in rat plasma using peptide nucleic acid probe and HPLC with fluorescence detection

(2017) Qingguo Tian et al.   Bioanalysis

Reduction of metal adducts in oligonucleotide mass spectra in ion-pair reversed-phase chromatography/mass spectrometry analysis

(2016) Robert E. Birdsall et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Elucidation of the Biotransformation Pathways of a Galnac3-conjugated Antisense Oligonucleotide in Rats and Monkeys

(2016) Colby S Shemesh et al.   Molecular Therapy-Nucleic Acids

Knocking down disease: a progress report on siRNA therapeutics

(2015) Anders Wittrup et al.   NATURE REVIEWS GENETICS

Application of RNA interference in treating human diseases

(2011) S. Abdolhamid Angaji et al.   JOURNAL OF GENETICS

Improvement of peak shape in aqueous normal phase analysis of anionic metabolites

(2011) Joseph J. Pesek et al.   JOURNAL OF SEPARATION SCIENCE

Bioanalytical LC–MS of therapeutic oligonucleotides

(2011) William D van Dongen et al.   Bioanalysis

Oligonucleotide bioanalysis: sensitivity versus specificity

(2011) Laixin Wang   Bioanalysis

RNAi and small interfering RNAs in human disease therapeutic applications

(2010) Monica R. Lares et al.   TRENDS IN BIOTECHNOLOGY

Assessment of siRNA pharmacokinetics using ELISA-based quantification

(2009) Eun-Joong Kim et al.   JOURNAL OF CONTROLLED RELEASE

Metabolite identification of small interfering RNA duplex by high-resolution accurate mass spectrometry

(2008) Yan Zou et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY