Article
Environmental Sciences
Michal Jacek Jedrzejek, Agnieszka Mastalerz-Migas
Summary: This study investigated the rate and reasons for influenza vaccination among healthcare workers during the 2018/19 and 2019/20 influenza seasons. The findings showed that males, physicians, and personnel from primary health-care settings were more likely to be vaccinated. Barriers to vaccination were mainly caused by misconceptions and organizational factors.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Immunology
Walid Al-Qerem, Anan Jarab, Abdel Qader AlBawab, Alaa Hammad, Badi'ah Alazab, Daoud Abu Husein, Judith Eberhardt, Fawaz Alasmari
Summary: This study examines the knowledge, attitudes, and practices of diabetic patients towards the influenza vaccine, finding a low willingness among diabetic patients to get vaccinated. A positive attitude towards the influenza vaccine significantly reduces hesitancy, while longer duration of diabetes is associated with increased vaccine hesitancy. Lack of awareness of the benefits of the influenza vaccine is the primary reason for not getting vaccinated.
Article
Biotechnology & Applied Microbiology
Yu Ma, Cuixiu Wang, Fanghua Liu, Guixiong Lian, Shuxue Li, Qing He, Tiegang Li
Summary: Data collected from college students in Guangzhou, China showed a low HPV vaccine coverage rate of approximately 3.09%, with 55.57% of participants expressing hesitation towards vaccination. Factors influencing vaccination included urban residence, high monthly consumption, awareness of vaccination adaptive population, knowledge of infection-related risk factors, and belief in the effectiveness of the HPV vaccine. Further efforts, such as establishing national financial subsidies and enhancing health education, are needed to increase the vaccination rate in China.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Biotechnology & Applied Microbiology
Qinwen Luo, Lin Gan, Yu Xiong, Qin Li, Tao Chen, Xiaojun Tang
Summary: The study found that over half of healthcare workers in Chongqing had good knowledge and positive attitudes towards influenza and its vaccine, but only a small percentage had actually received the vaccine last year. Various strategies such as educational training and on-site vaccination are needed to improve overall vaccination coverage.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Public, Environmental & Occupational Health
Wesam S. Ahmed, Rana Abu Farha, Abdulsalam M. Halboup, Arwa Alshargabi, Ahmed Al-mohamadi, Eman Y. Abu-rish, Mohammed Zawiah, Yousf K. Al-Ashbat, Sayida Al-Jamei
Summary: In Yemen, there is no policy for seasonal influenza vaccination and the vaccine is not included in the national immunization program. The study found that only 11.3% of the participants received the seasonal influenza vaccine, despite most of them being knowledgeable about its transmission modes. The recommendation of physicians was the main motivator for vaccination.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Rheumatology
Ines Colmegna, Valeria Valerio, Vincent Gosselin-Boucher, Guillaume Lacoste, Sara Labbe, Kim L. Lavoie, Elizabeth Hazel, Brian Ward, Marie Hudson, Sandra Pelaez
Summary: The study aimed to assess perspectives of RA patients and healthcare professionals on barriers and facilitators regarding influenza and pneumococcal vaccines. Results showed that vaccine acceptance is influenced by contextual, individual, and vaccine-related factors.
Article
Biotechnology & Applied Microbiology
Nehal Alharbi, Areej Almutiri, Futon Alotaibi, Amal Ismail
Summary: This study evaluated healthcare workers' perceptions of influenza vaccination in the Qassim region of Saudi Arabia. The majority of participants had good knowledge and positive perceptions, while over 10% had negative perceptions. Nationality and history of previous vaccination significantly contributed to negative perceptions.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Immunology
Yunhyung Kwon, Young June Choe, Jae-Won Yun, Hee Kyoung Kim, Sungnam Kim, Chaemin Chun, Yeon Haw Jung, HeeJung Kim, Hyun-kyung Oh, Yeonkyoeng Lee, Jae Young Lee, Seon Kui Lee, Young-Joon Park
Summary: Increased awareness of adverse events following immunization has the potential to disrupt vaccination programs, as demonstrated by a significant decline in vaccination coverage in South Korea following media reports of vaccine-related deaths. Vaccine coverage rates were found to be associated with media coverage, emphasizing the importance of continued vaccine safety surveillance and transparent risk communication to maintain public trust in vaccines.
Article
Immunology
Sylwia Kalucka, Izabela Grzegorczyk-Karolak
Summary: This study found that the main reasons for medical students refusing influenza vaccination included underestimating the vaccine's effectiveness, the need for payment, lack of time or opportunity, lack of vaccination promotion, and negative attitudes toward the flu vaccine.
Article
Immunology
Yamna Ali, Pierre-Philippe Piche-Renaud, Elahe Karimi-Shahrbabak, Daniel S. Farrar, Sarah Abu Fadaleh, Sharon Burey, Shaun K. Morris
Summary: This study examined the perception, practices, and barriers of pediatricians in Ontario regarding SARS-CoV-2 vaccination in children, particularly those aged 5 to 11 years. The majority of pediatricians were likely to recommend COVID-19 vaccination for this age group, perceived the vaccines as safe and effective, and felt confident in counseling caregivers. However, there is still a need for further training and capacity development.
Article
Biotechnology & Applied Microbiology
Sawsan Mubarak, Hadeel Alghawrie, Bayan Qaddumi
Summary: This study examines the knowledge, attitudes, concerns, behaviors, and barriers related to seasonal influenza vaccination among healthcare workers in the oncology setting during the COVID-19 pandemic. The study found that the coverage rates for seasonal influenza vaccination showed a significant increase from 2019 (65%) to 2020 (81%), despite the challenges posed by the pandemic. Furthermore, the participants expressed a strong willingness to receive the vaccine in the autumn of 2021 and exhibited good knowledge about it.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2023)
Article
Public, Environmental & Occupational Health
I. Tsiligianni, I Bouloukaki, G. Papazisis, A. Paganas, E. Chatzimanolis, M. Kalatharas, I. Platakis, I. Tirodimos, T. Dardavesis, Z. Tsimtsiou
Summary: Insufficient adult vaccination coverage rates remain an international challenge. This study explored vaccination coverage and predictors of vaccine uptake in Greece and found that perception of disease risk, concerns about side-effects and efficacy, and mistrust in pharmaceutical companies were common factors associated with vaccine uptake. The strongest predictor of vaccination status was the doctor's recommendation, and being well-informed about each vaccine also influenced uptake.
Article
Endocrinology & Metabolism
Haolong Li, Fan Ping, Xiaomeng Li, Zhihong Wang, Jianzhong Xiao, Hongwei Jiang, Yaoming Xue, Jinxing Quan, Hebin Yao, Xianling Zheng, Yanming Chen, Yufeng Li, Xiaohua Yu, Lingling Xu, Xinxin Feng, Siyu Wang, Yongzhe Li, Xinhua Xiao
Summary: There is a high proportion of COVID-19 vaccine coverage among patients with DM in China, but concerns about vaccine safety affect vaccination behavior. The side effects of the vaccine are self-limiting for DM patients.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Clinical Neurology
Bhaskar Roy, Tess Litchman, Tara Torabi, Richard J. Nowak
Summary: The survey revealed varying recommendations among neurologists regarding influenza vaccination in patients with MG, CIDP, and GBS, despite existing guidelines. There is an unmet need for clearer professional society recommendations and education to address this apparent knowledge gap.
Article
Immunology
Mark G. Thompson, Giselle Soto, Alon Peretz, Gabriella Newes-Adeyi, Young M. Yoo, Avital Hirsch, Mark A. Katz, Yeny Tinoco, Yonat Shemer Avni, Eduardo Ticona, Ryan Malosh, Emily Martin, Eduardo Matos, Sue Reynolds, Meredith Wesley, Jill Ferdinands, Angela Cheung, Min Levine, Eduar Bravo, Carmen Sofia Arriola, Maria Ester Castillo, Juan Carlos Castro, Fatimah Dawood, David Greenberg, Joan Manuel Neyra Quijandria, Eduardo Azziz-Baumgartner, Arnold Monto, Ran D. Balicer
Summary: Estimates of IVE were null using person-time models during six study seasons in Israel and Peru.
Article
Medicine, General & Internal
You Li, Xin Wang, Dianna M. Blau, Mauricio T. Caballero, Daniel R. Feikin, Christopher J. Gill, Shabir A. Madhi, Saad B. Omer, Eric A. F. Simoes, Harry Campbell, Ana Bermejo Pariente, Darmaa Bardach, Quique Bassat, Jean-Sebastien Casalegno, Giorgi Chakhunashvili, Nigel Crawford, Daria Danilenko, Lien Anh Ha Do, Marcela Echavarria, Angela Gentile, Aubree Gordon, Terho Heikkinen, Q. Sue Huang, Sophie Jullien, Anand Krishnan, Eduardo Luis Lopez, Josko Markic, Ainara Mira-Iglesias, Hannah C. Moore, Jocelyn Moyes, Lawrence Mwananyanda, D. James Nokes, Faseeha Noordeen, Evangeline Obodai, Nandhini Palani, Candice Romero, Vahid Salimi, Ashish Satav, Euri Seo, Zakhar Shchomak, Rosalyn Singleton, Kirill Stolyarov, Sonia K. Stoszek, Anne von Gottberg, Danielle Wurzel, Lay-Myint Yoshida, Chee Fu Yung, Heather J. Zar, Harish Nair
Summary: Respiratory syncytial virus (RSV) plays a significant role in morbidity and mortality burden globally in children aged 0-60 months, especially during the first 6 months of life and in low-income and middle-income countries. Passive immunization programs targeting RSV could have a substantial effect on reducing disease burden.
Article
Immunology
Anna Turkova, Hylke Waalewijn, Man K. Chan, Pauline D. J. Bollen, Mutsa F. Bwakura-Dangarembizi, Adeodata R. Kekitiinwa, Mark F. Cotton, Abbas Lugemwa, Ebrahim Variava, Grace Miriam Ahimbisibwe, Ussanee Srirompotong, Vivian Mumbiro, Pauline Amuge, Peter Zuidewind, Shabinah Ali, Cissy M. Kityo, Moherndran Archary, Rashida A. Ferrand, Avy Violari, Diana M. Gibb, David M. Burger, Deborah Ford, Angela Colbers
Summary: This study evaluated the safety and pharmacokinetics of twice-daily dosing of dolutegravir in children receiving rifampicin for HIV-associated tuberculosis. The results showed that twice-daily dosing of dolutegravir was safe and effective in overcoming the enzyme-inducing effect of rifampicin in children, providing a practical antiretroviral therapy option for children with HIV-associated TB.
Article
Immunology
Miriam Moscoso, Juan A. Vallejo, Maria P. Cabral, Patricia Garcia, Victor Fuentes-Valverde, Eva Gato, Jorge Arca-Suarez, Pablo Aja-Macaya, German Bou
Summary: This article describes a prototype vaccine for preventing Klebsiella pneumoniae infections, which is constructed using a glutamate racemase-deficient mutant. The results show that this mutant can induce a strong immune response and provide cross-protection against systemic infections caused by highly virulent and multidrug-resistant strains of K. pneumoniae, with a high level of safety.
Article
Public, Environmental & Occupational Health
Michelle B. Shin, Patricia J. Garcia, Mary Elizabeth Dotson, Maria Valderrama, Marina Chiappe, Nimmi Ramanujam, Marlee Krieger, Kristjana Asbjornsdottir, Ruanne Barnabas, Sarah J. Iribarren, Sarah Gimbel
Summary: The study evaluated the relational and financial empowerment of Hope Ladies in a social entrepreneurship program in Peru. Both interviews and surveys indicated that the Hope Ladies experienced increased empowerment in areas such as resources, agency, and achievements. Survey results showed improvements in social contacts, healthcare visits, confidence in discussing reproductive topics, and ability to make household decisions about money.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Maria Jesus Rios-Blancas, Victoria Pando-Robles, Christian Razo, Cesar P. Carcamo, Walter Mendoza, Kevin Pacheco-Barrios, J. Jaime Miranda, Van Charles Lansingh, Takele Gezahegn Demie, Manika Saha, Osaretin Christabel Okonji, Arzu Yigit, Lucero Cahuana-Hurtado, Pamela R. Chacon-Uscamaita, Eduardo Bernabe, Carlos Culquichicon, Jesus Lorenzo Chirinos-Caceres, Rosario Cardenas, Jacqueline Elizabeth Alcalde-Rabanal, Francisco J. Barrera, Beatriz Paulina Ayala Quintanilla, Seyed Afshin Shorofi, Nuwan Darshana Wickramasinghe, Nuno Ferreira, Louay Almidani, Vivek Kumar Gupta, Hanie Karimi, Daniel Shewaye Alayu, Catherine P. Benziger, Takeshi Fukumoto, Ebrahim Mostafavi, Elrashdy Moustafa Mohamed Redwan, Mesfin Gebrehiwot, Khaled Khatab, Ai Koyanagi, Fiorella Krapp, Seung Lee, Maryam Noori, Ibrahim Qattea, Victor Daniel Rosenthal, Joseph W. Sakshaug, Birhanu Wagaye, Iman Zare, Doris V. Ortega-Altamirano, Efren Murillo-Zamora, Dominique Vervoort, Diego Augusto Santos Silva, Abderrahim Oulhaj, Brenda Yuliana Herrera-Serna, Rahul Mehra, Mehrdad Amir-Behghadami, Nasrin Adib, Sandra Cortes, Anh Kim Dang, Binh Thanh Nguyen, Ali H. Mokdad, Simon I. Hay, Christopher J. L. Murray, Rafael Lozano, Patricia J. Garcia
Summary: Using data from the Global Burden of Disease Study (2019), this study assessed mortality and disability trends in Peru from 1990 to 2019. Significant improvements were observed in life expectancy and child survival, but there was an increase in the burden of non-communicable diseases. Peru had one of the highest rates of lower respiratory infections in the Latin American region before the COVID-19 pandemic.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
Alexandra Compagnucci, Man K. Chan, Yacine Saidi, Tim R. Cressey, Alasdair Bamford, Yoann Riault, Alexandra Coelho, Aoife Nolan, Suwalai Chalermpantmetagul, Gabija Morkunaite, Pauline Amuge, Victor Musiime, Avy Violari, Mark Cotton, Adeodata R. Kekitiinwa, Elizabeth Kaudha, Marisa Groenewald, Afaaf A. Liberty, Suparat Kanjanavanit, Alla Volokha, Rosa Bologna, Noris Pavia Ruz, Luis Prieto Tato, Paolo Paioni, Laura Marques, Veronique Reliquet, Tim Niehues, Steven B. Welch, Deborah Ford, Carlo Giaquinto, Diana M. Gibb, Abdel Babiker, Jose Tomas Ramos Amador
Summary: This study compared the efficacy and safety of once-daily integrase inhibitor (INSTI) with boosted darunavir (DRV/r) regimen to standard-of-care (SOC) triple antiretroviral therapy (ART) in virologically-suppressed children living with HIV. The results showed that switching to INSTI + DRV/r was non-inferior in terms of virological suppression and safety, but there were small but significant differences in CD4 count, HDL-cholesterol, weight, and BMI between the two groups at 48 weeks of follow-up. This study provides evidence for a nucleoside reverse transcriptase inhibitor (NRTI)-sparing regimen for children and adolescents.
Article
Public, Environmental & Occupational Health
Paola A. Torres-Slimming, Cesar P. Carcamo, Carlee J. Wright, Guillermo Lancha, Carol Zavaleta-Cortijo, Nia King, James Ford, Sherilee L. Harper, P. J. Garcia
Summary: This study examined the prevalence of childhood diarrhea and access to water and sanitation in 10 Shawi Indigenous communities in the Peruvian Amazon. It found that children living in households with latrines and water treatment methods were more likely to experience diarrhea. These findings highlight the importance of addressing local risk factors and prioritizing Indigenous communities in water, sanitation, and hygiene initiatives.
RURAL AND REMOTE HEALTH
(2023)
Article
Pediatrics
Anna Turkova, Ellen White, Adeodata R. Kekitiinwa, Vivian Mumbiro, Elizabeth Kaudha, Afaaf Liberty, Grace Miriam Ahimbisibwe, Tumelo Moloantoa, Ussanee Srirompotong, Nozibusiso Rejoice Mosia, Thanyawee Puthanakit, Robin Kobbe, Claudia Fortuny, Hajira Kataike, Dickson Bbuye, Sathaporn Na-Rajsima, Alexandra Coelho, Abbas Lugemwa, Mutsa F. Bwakura-Dangarembizi, Nigel Klein, Hilda A. Mujuru, Cissy Kityo, Mark F. Cotton, Rashida A. Ferrand, Carlo Giaquinto, Pablo Rojo, Avy Violari, Diana M. Gibb, ODYSSEY Trial Team
Summary: This study evaluated the neuropsychiatric manifestations in children and adolescents treated with dolutegravir-based treatment compared to alternative antiretroviral therapy. Numerically, more participants in the dolutegravir group reported psychiatric events and suicidal ideation than those in the standard-of-care group, but these differences should be interpreted cautiously in an open-label trial.
LANCET CHILD & ADOLESCENT HEALTH
(2023)
Article
Immunology
Kelsey M. Sumner, Lindsey M. Duca, Carmen Sofia Arriola, Joan Neyra, Giselle Soto, Candice Romero, Yeny Tinoco, Francisco Nogareda, Eduardo Matos, Victor Chavez, Maria Castillo, Eduar Bravo, Juan Castro, Mark Thompson, Eduardo Azziz-Baumgartner
Summary: Despite government subsidies, the influenza vaccination uptake is low among healthcare personnel in Peru. A study was conducted to explore the knowledge, attitudes, and practices of healthcare personnel regarding influenza illness and its impact on vaccination frequency.
Letter
Medicine, General & Internal
Barbara Stocking, Lawrence Gostin, Jane Halton, Jorge Saavedra, Patricia Garcia, Ricardo Baptiste Leite, Jemilah Mahmood, Winnie Mpanju, Angel Gurria, Elil Renganathan
Review
Health Care Sciences & Services
Jesus Medina-Ranilla, Laura Angelica Espinoza, Agustina Mazzoni, Javier Roberti, Ezequiel Garcia-Elorrio, Hannah Hogan Leslie, Patricia Jannet Garcia
Summary: This study conducted a systematic review on the measurement of healthcare quality in Latin America and the Caribbean (LAC) and found that the current measurement methods are inconsistent. Satisfaction is the most commonly measured quality domain, but its use in accountability and quality improvement is limited. It is necessary to establish a more systematic, regular, and comprehensive healthcare quality assessment system, led collaboratively by researchers, governments, and policymakers.
HEALTH POLICY AND PLANNING
(2023)
Article
Immunology
Carmen S. Arriola, Giselle Soto, Matthew Westercamp, Susan Bollinger, Angelica Espinoza, Max Grogl, Alejandro Llanos-Cuentas, Eduardo Matos, Candice Romero, Maria Silva, Rachel Smith, Natalie Olson, Michael Prouty, Eduardo Azziz-Baumgartner, Fernanda C. Lessa
Summary: This study evaluated the vaccine effectiveness among healthcare personnel in two hospitals in Lima, Peru after receiving COVID-19 vaccination. The results showed an effectiveness of 95% among fully vaccinated participants and 100% among partially vaccinated participants. These findings can provide valuable information for vaccination efforts in the region.
EMERGING INFECTIOUS DISEASES
(2022)
Article
Immunology
Pauline Amuge, Abbas Lugemwa, Ben Wynne, Hilda A. Mujuru, Avy Violari, Cissy M. Kityo, Moherndran Archary, Ebrahim Variava, Ellen White, Rebecca M. Turner, Clare Shakeshaft, Shabinah Ali, Kusum J. Nathoo, Lorna Atwine, Afaaf Liberty, Dickson Bbuye, Elizabeth Kaudha, Rosie Mngqibisa, Modehei Mosala, Vivian Mumbiro, Annet Nanduudu, Rogers Ankunda, Lindiwe Maseko, Adeodata R. Kekitiinwa, Carlo Giaquinto, Pablo Rojo, Diana M. Gibb, Anna Turkova, Deborah Ford
Summary: This study aimed to assess the efficacy of dolutegravir-based antiretroviral therapy (ART) in young children living with HIV. The results showed that dolutegravir-based ART was superior to standard care in terms of treatment failure and safety. The findings of this study provide better treatment options for young children and support the alignment of adult and pediatric treatment.
Article
Health Care Sciences & Services
Michelle B. Shin, Patricia J. Garcia, Enrique M. Saldarriaga, Jose L. Fiestas, Kristjana H. Asbjornsdottir, Sarah J. Iribarren, Ruanne Barnabas, Sarah Gimbel
Summary: This study estimated the total and unit costs associated with a community-based HPV self-sampling program in Peru. The findings suggest that the implementation of this program has competitive prices and is likely to be feasible in Peru.
LANCET REGIONAL HEALTH-AMERICAS
(2022)
Review
Health Care Sciences & Services
Felicia Marie Knaul, Hector Arreola-Ornelas, Beverley M. Essue, Renu Sara Nargund, Patricia Garcia, Uriel Salvador Acevedo Gomez, Roopa Dhatt, Alheli Calderon-Villarreal, Pooja Yerramilli, Ana Langer
Summary: This viewpoint discusses the lack of gender diversity in medical leadership and the dearth of evidence on the gender dimensions of the health workforce in Latin America. Despite significant changes in the gender composition of the medical field in Latin America, there are entrenched gender inequities in the health sector employment pipeline, leading to under-representation of women in medical leadership. The article proposes recommendations to disrupt the status quo, value women in decision-making roles for health, and advocates for the measurement of equity in medical leadership as a national, regional, and global priority.
LANCET REGIONAL HEALTH-AMERICAS
(2022)