Article
Engineering, Environmental
Atiye Ahmadireskety, Bianca F. Da Silva, Nicole M. Robey, Thomas E. Douglas, Joe Aufmuth, Helena M. Solo-Gabriele, Richard A. Yost, Timothy G. Townsend, John A. Bowden
Summary: This study analyzed 117 street sweeping samples for PFAS, with 56 samples collected from Gainesville, Florida. PFCAs were the dominant class of PFAS in Gainesville, and PFOA and PFOSlin were the most frequently detected PFAS. Additionally, this study documented the first-time detection of hexadecafluorosebacic acid and perfluoro-3,6,9-trioxaundecane-1,11-dioic acid within environmental samples.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Environmental
Marzieh Shojaei, Naveen Kumar, Jennifer L. Guelfo
Summary: This study evaluated AFFF and AFFF-impacted soils using two soil extraction methods, TOP assay, and SQ analysis. The results suggest that routine application of an acid extraction step in PFAS-impacted soils does not provide advantages. Suspect screening analysis of post-TOP samples identified eight classes of PFAS, some of which may have persistence in the environment and require more routine monitoring.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Damien Moodie, Timothy Coggan, Kathryn Berry, Adam Kolobaric, Milena Fernandes, Elliot Lee, Suzie Reichman, Dayanthi Nugegoda, Bradley O. Clarke
Summary: Biosolids samples from 19 Australian WWTPs were analyzed for 44 PFAS, with di-substituted phosphate esters being the dominant compound class contributing 45% of total PFAS mass. Higher PFAS concentrations were observed in urban locations, and there was a weak correlation between PFAS mass and percentage industrial waste contribution in WWTPs.
Article
Environmental Sciences
Frank Thomas Lange, Marco Scheurer, Christian Bierreth, Werner Borho, Ann-Kathrin Seeger, Peter Dreher, Thomas Noeltner
Summary: Batch leaching tests are valuable for assessing low PFAS levels in soils. Drying soil samples at ambient temperature or at 40 degrees C before the leaching process leads to higher PFAS leachate levels. The effect is greater for PFCAs than for PFSAs.
Review
Environmental Sciences
Sudarshan Kurwadkar, Jason Dane, Sushil R. Kanel, Mallikarjuna N. Nadagouda, Ryan W. Cawdrey, Balram Ambade, Garrett C. Struckhoff, Richard Wilkin
Summary: Per- and polyfluoroalkyl substances (PFAS), as anthropogenic organic pollutants, are widely distributed in the aquatic environment and have adverse effects on human health and ecology. This review critically evaluates the global occurrence and distribution of PFAS in water and discusses the evolving regulatory responses to mitigate the risks associated with PFAS. The study highlights the need for international cooperation in managing PFAS contamination.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Jennifer P. Pascali, Elena Piva, Maria Paola Bonasoni, Costanza Migliavacca, Anna Seidenari, Paolo Fais
Summary: The placenta plays an important role in transferring nutrients, oxygen, and drugs from the mother to the fetus. This study analyzed the levels of per- and polyfluoroalkyl substances (PFAS) in placenta tissue and found that these compounds were present in all samples, indicating their widespread presence in the population.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Alina Timshina, Juan J. Aristizabal-Henao, Bianca F. Da Silva, John A. Bowden
Summary: The study found PFAS in paper and other plant-based drinking straws, possibly due to the use of PFAS during manufacturing. Twenty-one PFAS were detected in the straws, with a wide range of semi-volatile PFAS concentrations, and approximately two-thirds of the total extractable PFAS leached after being soaked in hot water.
Review
Agricultural Engineering
Zhiming Zhang, Dibyendu Sarkar, Jayanta Kumar Biswas, Rupali Datta
Summary: PFAS are widely used chemicals due to their stability, but their toxicity and persistence in the environment have raised concerns. Research on biodegradation pathways and future directions are important for the removal of PFAS pollutants.
BIORESOURCE TECHNOLOGY
(2022)
Article
Engineering, Environmental
Yoon Jeong, Khushali Vyas, Joseph Irudayaraj
Summary: This study investigates the toxicity of PFAS on bacteria in a biofilm-like niche provided by hydrogel-based core-shell beads. The findings show that Escherichia coli MG1655 strain confined in hydrogel beads exhibit altered physiological characteristics compared to their susceptible counterpart cultivated under planktonic conditions. The study suggests that soft-hydrogel engineering platforms may protect microorganisms from environmental contaminants.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Review
Environmental Sciences
Ashenafi Berhanu, Ishmael Mutanda, Ji Taolin, Majjid A. Qaria, Bin Yang, Daochen Zhu
Summary: Since the 1950s, large amounts of PFAS have been dumped into the environment, causing significant contamination. PFAS are resistant to degradation and have adverse effects on health and the environment. Traditional physicochemical methods for PFAS treatment have drawbacks, making microbial degradation and enzymatic treatment highly sought after. This review provides an overview of PFAS classification, properties, and interaction with the environment, and discusses recent developments in microbial degradation, transformation routes, and challenges in bioremediation approaches.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Hue T. Nguyen, Michael S. McLachlan, Ben Tscharke, Phong Thai, Jennifer Braeunig, Sarit Kaserzon, Jake W. O'Brien, Jochen F. Mueller
Summary: Wastewater treatment plants in Australia are significant sources of PFAS, as shown in this study which measured PFAS in the influent of 76 municipal WWTPs. The study found that PFOS, PFHxS, and PFHxA were the most common PFAS detected. The per capita background release of Sigma(12) PFAS in Australia was estimated to be 8.1-24 μg/d per person, with contributions from catchment specific point sources.
Article
Food Science & Technology
K. L. Vorst, Neal Saab, Paulo Silva, Greg Curtzwiler, Abby Steketee
Summary: PFAS are synthetic chemicals with a history of use in various products, and high levels of exposure may have adverse health effects. Research gaps exist in understanding human exposure to PFAS from food and food packaging. Key discussions at the symposium focused on analytical methods, exposure routes, and potential health effects of PFAS.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Health Care Sciences & Services
Hao Tian, Christy Gaines, Lori Launi, Ana Pomales, Germaine Vazquez, Amanda Goharian, Bradley Goodnight, Erica Haney, Christopher M. Reh, Rachel D. Rogers
Summary: This study examines how social media is used in the United States to share, disseminate, and engage in public discussions of per- and polyfluoroalkyl substances (PFAS). The findings indicate an increasing interest and awareness of PFAS among social media users, highlighting the perceived urgency of understanding this emerging contaminant and its potential health impacts.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Environmental Sciences
Annelise J. Blomberg, Yu-Hsuan Shih, Carmen Messerlian, Louise Helskov Jorgensen, Pal Weihe, Philippe Grandjean
Summary: This study found that childhood exposure to PFAS may be associated with elevated serum lipid concentrations, with stronger positive associations between PFASs and TC and LDL-C in girls, and stronger positive associations with HDL-C in boys. In repeated measure models, exposure period was a significant modifier of PFAS effects.
ENVIRONMENTAL RESEARCH
(2021)
Article
Environmental Sciences
Huanqiang Wang, Kai Wei, Zhixin Wu, Fucun Liu, Danhua Wang, Xianzheng Peng, Yongyou Liu, Jida Xu, A'pei Jiang, Yan Zhang
Summary: Some PFAS (e.g., PFNA, PFOA) exposures were found to be associated with semen quality, particularly with lower sperm progressive motility. In studies with sample sizes exceeding 200 people, PFNA exposure was related to sperm morphology.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Abdullah Akhdhar, Deia Abd El-Hady, Mohammed Almutairi, Khulood K. Alnabati, Abdullah Alowaifeer, Sultan Alhayyani, Hassan M. Albishri, Abdullah S. Al-Bogami
Summary: The study found that polyethylene laminated disposable paper cups may contain metals and ions in hot water, although the concentrations are below drinking water standards. Specifically, vanadium and fluoride ions may pose health risks after long-term ingestion. Adjustments in cup composition are needed to avoid the release of contaminants.
ENVIRONMENTAL CHEMISTRY LETTERS
(2022)
Article
Environmental Sciences
A. M. Salama, R. M. A. Abedin, K. Z. Elwakeel
Summary: The study evaluated the role of greenly prepared magnetic iron oxide nanoparticles (Fe3O4 NPs) on bioremediation of dairy effluent, finding that Fe3O4 NPs enhance bacterial growth, with an optimum concentration of around 40 mg L-1. Cultures incorporating Fe3O4 NPs showed significant improvement in bioremediation compared to pure cultures.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2022)
Article
Environmental Sciences
Mohammed F. Hamza, Yuezhou Wei, Mahmoud S. Khalafalla, Neveen S. Abed, Amr Fouda, Khalid Z. Elwakeel, Eric Guibal, Nora A. Hamad
Summary: Urea and thiourea have been deposited on the surface of silica beads for the recovery of U(VI) and Th(IV). The sorbents exhibit fast uptake kinetics and high sorption capacities. They also show excellent stability and preferential adsorption of U(VI) and Th(IV) over other metals.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Chemistry, Multidisciplinary
Ahmed M. Elgarahy, M. G. Eloffy, Ahmed Hammad, Ayman N. Saber, Dina M. El-Sherif, Ahmed Mohsen, Mohamed Abouzid, Khalid Z. Elwakeel
Summary: This article reviews various methods of dihydrogen production from wastewater and their applications, highlighting the need for cleaner and sustainable production methods.
ENVIRONMENTAL CHEMISTRY LETTERS
(2022)
Article
Environmental Sciences
Ahmed M. Elgarahy, Bandar A. Al-Mur, Abdullah Akhdhar, Hamdy A. El-Sadik, Mohamed Azab El-Liethy, Khalid Z. Elwakeel, Abeer M. Salama
Summary: This study successfully isolated three bacterial species with potential as multifunctional biosorbents from low-level liquid radioactive wastes. These bacteria exhibited high loading capacities for cerium and cobalt metal ions, making them promising for the removal of toxic heavy metals from liquid waste effluents.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Environmental Sciences
Ahmed M. Elgarahy, M. G. Eloffy, Ahmed Alengebawy, Dina M. El-Sherif, Mohamed S. Gaballah, Khalid Z. Elwakeel, Mohamed El-Qelish
Summary: Food waste contains various nutrients that can be reused to produce value-added products or converted into green energy sources, such as biogas, biohydrogen, and biodiesel, as an alternative to nonrenewable fuels. Laboratory studies have shown that biochemical production using food waste is as effective as using pure carbon sources. This review article aims to provide a global perspective on the approaches used to turn food waste into usable products and green energy sources. It discusses the sources, types, impacts, characteristics, pre-treatment strategies, and potential management of food waste for value-added product generation. The reviewed articles also highlight the feasibility of energy recovery from food waste through various transformation processes, as well as the socioeconomic, environmental, and engineering aspects related to food waste management.
ENVIRONMENTAL RESEARCH
(2023)
Article
Engineering, Environmental
Bridger J. Ruyle, Lara Schultes, Denise M. Akob, Cassandra R. Harris, Michelle M. Lorah, Simon Vojta, Jitka Becanova, Shelley McCann, Heidi M. Pickard, Ann Pearson, Rainer Lohmann, Chad D. Vecitis, Elsie M. Sunderland
Summary: Drinking water supplies in the US have been contaminated by PFAS in AFFF used in firefighting and fire-training activities. The C6 precursors in 3M AFFF can be transformed into PFHxS through microbial oxidation. This study provides evidence of the biotransformation of C6 sulfonamido precursors in representative microcosms, highlighting the role of ammonia-oxidizing archaea and nitrite-oxidizing bacteria. Understanding the interrelationship between precursor biotransformation and nitrogen cycling can inform site remediation efforts.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Review
Engineering, Chemical
Ahmed M. Elgarahy, M. G. Eloffy, Eric Guibal, Huda M. Alghamdi, Khalid Z. Elwakeel
Summary: Polymeric materials have thrived globally due to their versatility and durability, but the reliance on petroleum-based polymers has led to environmental issues. Natural biopolymers from biomass offer a promising solution to replace petroleum-based polymers, with advantages of low cost, environmental friendliness, and user-friendliness. The use of biopolymers is crucial in promoting a circular bioeconomy, and future environmental management and planning.
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2023)
Article
Environmental Sciences
Jilda Sofiana Buhani, Jilda Sofiana Dewi, Nadya Syarifatul Fajriyah, Mita Z. Rilyanti, Suharso, Sumadi, Khalid Elwakeel
Summary: This study modified carbon derived from rubber fruit shells, resulting in nAC-RFs-S through the use of a silane agent called 3-Aminopropyl-Triethoxysilane (APTES). The adsorbent was characterized using Infrared Spectrometer (IR) and Scanning Electron Microscopy-Energy Dispersive-X-ray (SEM-EDX). Batch adsorption experiments showed that nAC-RFs-S had optimal conditions for adsorbing Coomassie Brilliant Blue (CBB) and Methylene Blue (MB) dyes. The nAC-RFs-S adsorbent demonstrated remarkable effectiveness in adsorbing CBB and MB in solution, with the ability to be reused for multiple cycles.
WATER AIR AND SOIL POLLUTION
(2023)
Article
Environmental Sciences
Mita Buhani, Franciska Devi Rindi Suharso, Mita Rilyanti, Franciska Devi Rindi Antika, Laili Puji Z. Lestari, Sumadi, Muslim Ansori, Khalid Elwakeel
Summary: In this research, activated carbon obtained from rubber fruit shells (ACRPs) was modified with magnetite coating and silanization with triethoxyiphenylsilane (TEPS) to produce a new magnetic adsorbent (ACRPs-MS). The adsorption capacity and kinetics of the ACRPs-MS adsorbent were evaluated for methylene blue (MB) and crystal violet (CV) dyes in mono-component and bi-component solutions. The results showed that ACRPs-MS exhibited strong affinity towards both dyes and followed pseudo-second-order kinetics. The adsorbent could be reused multiple times and desorption was successfully achieved using 0.05 M HCl solution.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Environmental
Bridger J. Ruyle, Lara Schultes, Denise M. Akob, Cassandra R. Harris, Michelle M. Lorah, Simon Vojta, Jitka Becanova, Shelley McCann, Heidi M. Pickard, Ann Pearson, Rainer Lohmann, Chad D. Vecitis, Elsie M. Sunderland
Summary: Drinking water supplies in the US have been contaminated with PFAS from firefighting foams produced by 3M, which consist of C6 precursors. These precursors can be transformed through nitrification into PFHxS, a compound of regulatory concern. The study demonstrates the slow biotransformation of C6 precursors into PFHxS in microcosms, with the involvement of ammonia-oxidizing archaea and nitrite-oxidizing bacteria. Further understanding of the relationship between precursor biotransformation and nitrogen cycling would aid in site remediation efforts.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Buhani, Istikomah, Suharso, Sumadi, Sutarto, Huda M. Alghamdi, Khalid Z. Elwakeel
Summary: The modification of Tetraselmis sp. algae material with surfactant CTAB resulted in an effective adsorbent for the removal of anionic dyes from wastewater. The adsorption process followed pseudo-second-order kinetics and Freundlich adsorption isotherms. The reuse of the adsorbent showed high adsorption capacity even after multiple cycles.
Article
Engineering, Environmental
Bridger J. Ruyle, Heidi M. Pickard, Lara Schultes, Felicia Fredriksson, Amy L. Heffernan, Detlef R. U. Knappe, Heather L. Lord, Pingping Meng, Marc A. Mills, Kuria Ndungu, Philipp Roesch, Jan Thomas Rundberget, Daniel R. Tettenhorst, Jean Van Buren, Christian Vogel, Danielle C. Westerman, Leo W. Y. Yeung, Elsie M. Sunderland
Summary: Research on per- and polyfluoroalkyl substances frequently includes organofluorine measurements, but standardized methods are currently lacking. This study conducted an interlaboratory comparison and found that the measurements of extractable organofluorine (EOF) in groundwater and eel were consistent among most laboratories, while instrumental operation and potential uncertainties from blank contamination and incomplete inorganic fluorine removal were identified as major sources of measurement uncertainty. To accurately determine unknown organofluorine, analysts should carefully consider methodological uncertainties and differences in precision between measurements.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Environmental
M. G. Eloffy, Ahmed M. Elgarahy, Ayman N. Saber, Ahmed Hammad, Dina M. El-Sherif, Moustafa Shehata, Ahmed Mohsen, Khalid Z. Elwakeel
Summary: This review article summarizes patented approaches for hydrogen production from biomass, discusses the optimization of different prominent parameters to achieve the easiest way for hydrogen production, and briefly addresses operational parameters, technical challenges, and scalable improvement of each pathway.
CHEMICAL ENGINEERING JOURNAL ADVANCES
(2022)
Review
Materials Science, Multidisciplinary
Raed A. Mashabi, Ziya A. Khan, Khalid Z. Elwakeel
Summary: This study summarizes the use of chitosan (CS) or glycidyl methacrylate (GMA) as dye adsorbents and their modifications using different functional materials. It is found that CS and GMA derivatives have good water-purification properties and can effectively clean wastewater. Thorough knowledge of their adsorption capabilities is required for understanding how CS and GMA remove organic dyes from wastewater.
MATERIALS ADVANCES
(2022)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).