The Atherosclerosis Risk Variant rs2107595 Mediates Allele-Specific Transcriptional Regulation of HDAC9 via E2F3 and Rb1

Stroke genetics: discovery, biology, and clinical applications

(2019) Martin Dichgans et al.   LANCET NEUROLOGY

HDAC9 promotes brain ischemic injury by provoking IκBα/NF-κB and MAPKs signaling pathways

(2018) Shan Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A genome-wide survey of mutations in the Jurkat cell line

(2018) Louis Gioia et al.   BMC GENOMICS

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

(2018) Rainer Malik et al.   NATURE GENETICS

HDAC9 Polymorphism Alters Blood Gene Expression in Patients with Large Vessel Atherosclerotic Stroke

(2018) Natasha Shroff et al.   Translational Stroke Research

Global, Regional, and Country-Specific Lifetime Risks of Stroke, 1990 and 2016

(2018)   NEW ENGLAND JOURNAL OF MEDICINE

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

(2018) Nora Franceschini et al.   Nature Communications

Emerging Roles of Transcriptional Enhancers In Chromatin Looping And Promoter-Proximal Pausing Of RNA Polymerase II

(2017) Huan Meng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association analyses based on false discovery rate implicate new loci for coronary artery disease

(2017) Christopher P Nelson et al.   NATURE GENETICS

HOCOMOCO: towards a complete collection of transcription factor binding models for human and mouse via large-scale ChIP-Seq analysis

(2017) Ivan V Kulakovskiy et al.   NUCLEIC ACIDS RESEARCH

The Encyclopedia of DNA elements (ENCODE): data portal update

(2017) Carrie A Davis et al.   NUCLEIC ACIDS RESEARCH

Downregulation of HDAC9 inhibits cell proliferation and tumor formation by inducing cell cycle arrest in retinoblastoma

(2016) Yiting Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HDAC9 regulates ox-LDL-induced endothelial cell apoptosis by participating in inflammatory reactions

(2016) Qiang Dong   Frontiers in Bioscience-Landmark

The Coronary Artery Disease-associated Coding Variant in Zinc Finger C3HC-type Containing 1 (ZC3HC1) Affects Cell Cycle Regulation

(2016) Peter D. Jones et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The choice of phorbol 12-myristate 13-acetate differentiation protocol influences the response of THP-1 macrophages to a pro-inflammatory stimulus

(2016) Maria E. Lund et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Low-frequency and common genetic variation in ischemic stroke

(2016) Rainer Malik et al.   NEUROLOGY

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease

(2015) Lucas D. Ward et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Association Study of Peripheral Arterial Disease in a Japanese Population

(2015) Mitsuru Matsukura et al.   PLoS One

Histone Deacetylase 9 Represses Cholesterol Efflux and Alternatively Activated Macrophages in Atherosclerosis Development

(2014) Qiang Cao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Chromatin regulation: How complex does it get?

(2014) Karin Meier et al.   Epigenetics

Activation of mTOR modulates SREBP-2 to induce foam cell formation through increased retinoblastoma protein phosphorylation

(2013) K. L. Ma et al.   CARDIOVASCULAR RESEARCH

Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group

(2013) Mercedes Lobera et al.   Nature Chemical Biology

Evidence HDAC9 Genetic Variant Associated With Ischemic Stroke Increases Risk via Promoting Carotid Atherosclerosis

(2013) Hugh S. Markus et al.   STROKE

Histone Deacetylases 6 and 9 and Sirtuin-1 Control Foxp3+ Regulatory T Cell Function Through Shared and Isoform-Specific Mechanisms

(2012) U. H. Beier et al.   Science Signaling

Proteome-Wide Analysis of Disease-Associated SNPs That Show Allele-Specific Transcription Factor Binding

(2012) Falk Butter et al.   PLoS Genetics

Histone Deacetylase 9 (HDAC9) Regulates the Functions of the ATDC (TRIM29) Protein

(2010) Zhigang Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E2f1–3 Are Critical for Myeloid Development

(2010) Prashant Trikha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Negative regulators in homeostasis of naïve peripheral T cells

(2008) Jaime F. Modiano et al.   IMMUNOLOGIC RESEARCH