Role of Surface RGD Patterns on Protein Nanocages in Tumor Targeting Revealed Using Precise Discrete Models

Engineering of Bioinspired, Size-Controllable, Self-Degradable Cancer-Targeting DNA Nanoflowers via the Incorporation of an Artificial Sandwich Base

(2019) Lili Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Perspectives on the past, present, and future of cancer nanomedicine

(2018) Yu Seok Youn et al.   ADVANCED DRUG DELIVERY REVIEWS

Bioengineered cellular and cell membrane-derived vehicles for actively targeted drug delivery: So near and yet so far

(2018) Thanuja M.Y. et al.   ADVANCED DRUG DELIVERY REVIEWS

The effects of ligand valency and density on the targeting ability of multivalent nanoparticles based on negatively charged chitosan nanoparticles

(2018) Jing Cao et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Progress and challenges towards targeted delivery of cancer therapeutics

(2018) Daniel Rosenblum et al.   Nature Communications

A ribonucleoprotein octamer for targeted siRNA delivery

(2018) Wanyi Tai et al.   Nature Biomedical Engineering

Multivalent Ligand Binding to Cell Membrane Antigens: Defining the Interplay of Affinity, Valency, and Expression Density

(2018) Clifford M. Csizmar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting carbon nanotubes based on IGF-1R for photothermal therapy of orthotopic pancreatic cancer guided by optical imaging

(2018) Guan-Hua Lu et al.   BIOMATERIALS

Dual-Ratiometric Target-Triggered Fluorescent Probe for Simultaneous Quantitative Visualization of Tumor Microenvironment Protease Activity and pH in Vivo

(2017) Tiancong Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA-imprinted polymer nanoparticles with monodispersity and prescribed DNA-strand patterns

(2017) Tuan Trinh et al.   Nature Chemistry

Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression

(2017) Fengmei Pi et al.   Nature Nanotechnology

cRGD-functionalized reduction-sensitive shell-sheddable biodegradable micelles mediate enhanced doxorubicin delivery to human glioma xenografts in vivo

(2016) Yaqin Zhu et al.   JOURNAL OF CONTROLLED RELEASE

Site-Specific Surface Functionalization of Gold Nanorods Using DNA Origami Clamps

(2016) Chenqi Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transfer of molecular recognition information from DNA nanostructures to gold nanoparticles

(2016) Thomas G. W. Edwardson et al.   Nature Chemistry

Tumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies

(2016) Miriam Colombo et al.   Nature Communications

Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin αvβ3

(2016) Haojun Chen et al.   Theranostics

Controlled Self-Assembly of Proteins into Discrete Nanoarchitectures Templated by Gold Nanoparticles via Monovalent Interfacial Engineering

(2015) Lingzhi Ma et al.   ACS Applied Materials & Interfaces

Drug-Induced Self-Assembly of Modified Albumins as Nano-theranostics for Tumor-Targeted Combination Therapy

(2015) Qian Chen et al.   ACS Nano

Physical Chemistry of Nanomedicine: Understanding the Complex Behaviors of Nanoparticles in Vivo

(2015) Lucas A. Lane et al.   Annual Review of Physical Chemistry

Ferritin: A Versatile Building Block for Bionanotechnology

(2015) Günther Jutz et al.   CHEMICAL REVIEWS

Targeted PRINT Hydrogels: The Role of Nanoparticle Size and Ligand Density on Cell Association, Biodistribution, and Tumor Accumulation

(2015) Kevin G. Reuter et al.   NANO LETTERS

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Influence of ligand distribution on uptake efficiency

(2015) Veronika Schubertová et al.   Soft Matter

Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force

(2015) Cheng-han Yu et al.   Nature Communications

Investigating the Impact of Nanoparticle Size on Active and Passive Tumor Targeting Efficiency

(2014) Edward A. Sykes et al.   ACS Nano

Targeting efficiency of RGD-modified nanocarriers with different ligand intervals in response to integrin αvβ3 clustering

(2014) Zhaoming Guo et al.   BIOMATERIALS

Orientation-Controlled Conjugation of Haloalkane Dehalogenase Fused Homing Peptides to Multifunctional Nanoparticles for the Specific Recognition of Cancer Cells

(2013) Serena Mazzucchelli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals

(2013) Yiguang Wang et al.   NATURE MATERIALS

Particle shape enhances specificity of antibody-displaying nanoparticles

(2013) Sutapa Barua et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biotechnological approaches toward nanoparticle biofunctionalization

(2013) Svetlana Avvakumova et al.   TRENDS IN BIOTECHNOLOGY

In Vivo Targeting and Imaging of Tumor Vasculature with Radiolabeled, Antibody-Conjugated Nanographene

(2012) Hao Hong et al.   ACS Nano

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Designed Diblock Oligonucleotide for the Synthesis of Spatially Isolated and Highly Hybridizable Functionalization of DNA–Gold Nanoparticle Nanoconjugates

(2012) Hao Pei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of ligand density, receptor density, and nanoparticle size on cell targeting

(2012) Drew R. Elias et al.   Nanomedicine-Nanotechnology Biology and Medicine

Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities

(2012) Z. Cheng et al.   SCIENCE

Encapsulation of Gold Nanoparticles in a DNA Origami Cage

(2011) Zhao Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA origami: a quantum leap for self-assembly of complex structures

(2011) Thomas Tørring et al.   CHEMICAL SOCIETY REVIEWS

Monofunctionalization of Protein Nanocages

(2011) Feng Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Reexamination of Active and Passive Tumor Targeting by Using Rod-Shaped Gold Nanocrystals and Covalently Conjugated Peptide Ligands

(2010) Xiaohua Huang et al.   ACS Nano

Ligand-Clustered “Patchy” Nanoparticles for Modulated Cellular Uptake and In Vivo Tumor Targeting

(2010) Zhiyong Poon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery

(2010) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Endocytosis of nanomedicines

(2010) Gaurav Sahay et al.   JOURNAL OF CONTROLLED RELEASE

Frontiers in cancer nanomedicine: directing mass transport through biological barriers

(2010) Mauro Ferrari   TRENDS IN BIOTECHNOLOGY

Translocation and Endocytosis for Cell-penetrating Peptide Internalization

(2009) Chen-Yu Jiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A modeling analysis of the effects of molecular size and binding affinity on tumor targeting

(2009) M. M. Schmidt et al.   MOLECULAR CANCER THERAPEUTICS

Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticles

(2009) C. H. J. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient Site-Specific Labeling of Proteins via Cysteines

(2008) Younggyu Kim et al.   BIOCONJUGATE CHEMISTRY

Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers

(2008) F. Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Does a targeting ligand influence nanoparticle tumor localization or uptake?

(2008) Kathleen F. Pirollo et al.   TRENDS IN BIOTECHNOLOGY