Article
Optics
He Li, Hong-Gang Ye, Rui Cheng, Jiazhuang Guo, Zhi-Bin Liang, Ge Li, Qing Li, Cai-Feng Wang, Su Chen
Summary: The study presents a facile method for preparing red-emissive carbon dots for detecting veterinary drugs, utilizing the dual-emissive photoluminescence property. The carbon dots exhibit fast fluorescence response to several widely abused veterinary drugs and achieved low detection limits.
JOURNAL OF LUMINESCENCE
(2021)
Article
Biochemical Research Methods
Xiping Mei, Dongxiu Wang, Songbai Wang, Junfen Li, Chuan Dong
Summary: In this study, fluorescent carbon dots (CDs) doped with N and S atoms were successfully synthesized, exhibiting dual emission fluorescence at two separate wavelengths. The interaction between Cr (VI) ions and CDs led to a decrease in fluorescence at one wavelength and an increase at the other. This property allowed for the visualization detection of Cr (VI) in water samples. Additionally, the CDs were applied as fluorescent probes for cell imaging with dual emission fluorescence.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Spectroscopy
Xiaoping Chen, Jianwei Lin, Yafeng Zhuang, Siqi Huang, Jinghua Chen, Zhizhong Han
Summary: A new ratiometric fluorescence sensor is developed for the selective detection of chlorotetracycline (CTC) using dual-mode fluorescence method, demonstrating good selectivity and sensitivity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Adryanne Clermont-Paquette, Diego-Andres Mendoza, Amir Sadeghi, Alisa Piekny, Rafik Naccache
Summary: There is a need to develop novel nanosensors for the sensitive and facile detection of glyphosate pesticides in water. This study presents a dual emissive carbon dot system that can optically detect glyphosate at different pH levels. The system utilizes blue and red fluorescence emissions and employs a ratiometric self-referencing assay. The red fluorescence is quenched by glyphosate, while the unaffected blue fluorescence serves as a reference. These carbon dots can be used as cost-effective and simple environmental nanosensors for the detection of other pesticides and contaminants in water.
Article
Chemistry, Multidisciplinary
Jiaqing Guo, Aikun Liu, Yutian Zeng, Haojie Cai, Shuai Ye, Hao Li, Wei Yan, Feifan Zhou, Jun Song, Junle Qu
Summary: The study developed novel dual-emission nitrogen-doped carbon dots (NCDs) for sensitive detection of Cu2+ and ClO-, exhibiting excellent anti-interference ability and selectivity with a linear relationship between fluorescence intensity in different emissions for the two ions. The detection limits for Cu2+ and ClO- were very low, with good recovery rates in water samples, indicating a promising application prospect in real samples.
Article
Chemistry, Analytical
Qinhong Yin, Yijie Wang, Xuerong Li, Dezhi Yang, Yaling Yang, Cheng Yang, Yanqin Zhu
Summary: In this study, a novel nitr[ogen-doped carbon dot (N-CD) fluorescence sensor with a dual emission ratio was developed using microwave-assisted synthesis. The fluorescence of N-CDs at 350 nm was reduced in the presence of morphine (MOR), while the fluorescence at 456 nm increased substantially, due to the fluorescence inner filtration effect (IFE) between MOR and N-CDs. The sensor showed great potential for MOR detection with a linear range of 0.25-25 μg/mL and a detection limit of 71.8 ng/mL, and it successfully measured MOR speciation in various biological samples.
Article
Spectroscopy
Lin Yuan, Lizhen Liu, Zhi Mi, Meng Chen, Yunfeng Bai, Jun Qin, Feng Feng
Summary: In this paper, an innovative method based on intrinsic dual-emissive carbon dots (Y/B-CDs) was used to detect Amaranth (AMA). The method showed ratiometric detection and good linear ranges, and was able to detect AMA in beverages and candy.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Nanoscience & Nanotechnology
Fan Liu, Yuan Jiang, HaiBao Shao, Chunlei Wang, Shuhong Xu, Rong Zhang
Summary: This study reveals that the fluorescence of B/N-doped carbon dots can be precisely tuned by controlling the precursors' pH values and investigates the dual effects of pH on the structure and fluorescence of CDs. pH plays a role in the bonding process of CDs, affecting the formation of N-H and B-N bonds, as well as the crystallinity and defect-state fluorescence of the CDs.
Article
Chemistry, Analytical
Xiaorui Dong, Lihong Shi, Wei Zhou, Shaomin Shuang
Summary: Dual-emission carbon dots (D-CDs) were developed for ratiometric recognition of Co2+ and EDTA, displaying continuous color changes and visual quantification. The D-CDs exhibited dual emissions at 562 nm and 610 nm under 450 nm excitation. The fluorescence of D-CDs can be quenched by Co2+ and recovered by EDTA, enabling visual quantification of Co2+ and EDTA using a smartphone app.
MICROCHEMICAL JOURNAL
(2023)
Article
Biochemical Research Methods
Liying Jin, Xiaosong Wang, Xinyi Liu, Yuliang Jiang, Jian Shen
Summary: In this study, nitrogen-doped carbon quantum dots were synthesized as a fluorescent probe for the simultaneous detection of ferric ions and pyrophosphate anions. The developed probe has great significance in the field of life sciences and can have a positive impact on the health of the environment and organisms.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Bin Wang, Xiao-Qin Zhou, Jun-Ming Lin, Shu-Yu Liu, Cong-Hua Lu, Li-Juan Liu, Yu Chen, Li-Ping Yu
Summary: The study synthesized HPEI-CDs with concentration-modulated dual-excitation fluorescence property and successfully detected Fe3+ using them as a ratiometric sensor, demonstrating a wide linear response concentration range and low detection limit. The sensor showed good selectivity and anti-interference capacity due to the high concentration of HPEI-CDs.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Xiaoping Chen, Yafeng Zhuang, Jing Chen, Jianwei Lin, Jinghua Chen, Zhizhong Han
Summary: Novel norepinephrine modified carbon dots (NECDs) were prepared and showed improved fluorescence properties compared to unmodified carbon dots (CDs). A dual-mode sensing platform based on NECDs was developed for the detection of Cu2+ and biothiols, which exhibited high sensitivity and selectivity through fluorescence resonance energy transfer and absorption changes.
MICROCHEMICAL JOURNAL
(2022)
Article
Spectroscopy
Yecang Tang, Xuemei Dong, Minhui Wang, Beibei Guo
Summary: Novel dual-emission fluorescent nitrogen-doped carbon dots (N-CDs) were synthesized and used as a ratiometric fluorescent and colorimetric dual-signal probe for indigo carmine (IC) detection with high selectivity and sensitivity. The N-CDs showed dual-emitting peaks at 435 nm and 578 nm under a single excitation and the fluorescence at 578 nm was effectively quenched by IC. The addition of IC caused a linear increase in the ratiometric fluorescent value and a linear colorimetric response.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Spectroscopy
Lizhen Liu, Meng Chen, Lin Yuan, Zhi Mi, Caiqing Li, Zhixiong Liu, Zezhong Chen, Ligang Wang, Feng Feng, Luqi Wu
Summary: A novel ratiometric fluorescent probe based on dual-emission carbon dots was developed for sensitive detection of salicylic acid. The probe showed a good linear relationship and low detection limits, and demonstrated satisfactory performance in actual samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Xiufen Liao, Congjin Chen, Jielun Yang, Ruxia Zhou, Lulu Si, Quanlong Huang, Zuqiang Huang, Chunqiu Lv
Summary: N-doped carbon dots (N-CDs) were synthesized by hydrothermal treatment of cellobiose and urea, and a novel anti-false-positive mechanism for phosalone identification was achieved. The constructed sensor showed comparable accuracy and precision to the standard gas chromatographic (GC) method, with excellent recovery rates and low relative standard deviations (RSD).
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)