Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis

Host and parasite responses in human diffuse cutaneous leishmaniasis caused by L. amazonensis

(2019) Stephen M. Christensen et al.   PLoS Neglected Tropical Diseases

The Elderly Respond to Antimony Therapy for Cutaneous Leishmaniasis Similarly to Young Patients but Have Severe Adverse Reactions

(2018) Alexsandro Souza do Lago et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Association of Treatment of American Cutaneous Leishmaniasis Prior to Ulcer Development with High Rate of Failure in Northeastern Brazil

(2018) Alon Unger et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

The value of transcriptomics in advancing knowledge of the immune response and diagnosis in tuberculosis

(2018) Akul Singhania et al.   NATURE IMMUNOLOGY

Early Cutaneous Leishmaniasis Patients Infected With Leishmania braziliensis Express Increased Inflammatory Responses After Antimony Therapy

(2017) Rúbia S Costa et al.   JOURNAL OF INFECTIOUS DISEASES

plotROC: A Tool for Plotting ROC Curves

(2017) Michael C. Sachs   Journal of Statistical Software

Host blood RNA signatures predict the outcome of tuberculosis treatment

(2017) Ethan G. Thompson et al.   TUBERCULOSIS

CombiROC: an interactive web tool for selecting accurate marker combinations of omics data

(2017) Saveria Mazzara et al.   Scientific Reports

Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

(2017) Alicia Ponte-Sucre et al.   PLoS Neglected Tropical Diseases

CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production

(2017) Fernanda O. Novais et al.   PLoS Pathogens

Analytical Performance of Four Polymerase Chain Reaction (PCR) and Real Time PCR (qPCR) Assays for the Detection of Six Leishmania Species DNA in Colombia

(2017) Cielo M. León et al.   Frontiers in Microbiology

ImmQuant: a user-friendly tool for inferring immune cell-type composition from gene-expression data

(2016) Amit Frishberg et al.   BIOINFORMATICS

The Nlrp3 inflammasome, IL-1β, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice

(2016) Melanie Charmoy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A blood RNA signature for tuberculosis disease risk: a prospective cohort study

(2016) Daniel E Zak et al.   LANCET

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

(2016) Stephen M. Christensen et al.   PLoS Neglected Tropical Diseases

Lymphocytic Choriomeningitis Virus Expands a Population of NKG2D+CD8+T Cells That Exacerbates Disease in Mice Coinfected withLeishmania major

(2015) Erika J. Crosby et al.   JOURNAL OF IMMUNOLOGY

Genomic Profiling of Human Leishmania braziliensis Lesions Identifies Transcriptional Modules Associated with Cutaneous Immunopathology

(2015) Fernanda O. Novais et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Orchestrating high-throughput genomic analysis with Bioconductor

(2015) Wolfgang Huber et al.   NATURE METHODS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Protective and Pathological Functions of CD8+T Cells in Leishmania braziliensis Infection

(2014) Thiago Marconi Cardoso et al.   INFECTION AND IMMUNITY

Sensitive diagnosis of cutaneous leishmaniasis by lesion swab sampling coupled to qPCR

(2014) EMILY R. ADAMS et al.   PARASITOLOGY

Engagement of NKG2D on Bystander Memory CD8 T Cells Promotes Increased Immunopathology following Leishmania major Infection

(2014) Erika J. Crosby et al.   PLoS Pathogens

CD8+ Granzyme B+–Mediated Tissue Injury vs. CD4+IFNγ+–Mediated Parasite Killing in Human Cutaneous Leishmaniasis

(2013) Claire da Silva Santos et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-17 Mediates Immunopathology in the Absence of IL-10 Following Leishmania major Infection

(2013) Claudia Gonzalez-Lombana et al.   PLoS Pathogens

Cytotoxic T Cells Mediate Pathology and Metastasis in Cutaneous Leishmaniasis

(2013) Fernanda O. Novais et al.   PLoS Pathogens

PIP2-dependent regulation of Munc13-4 endocytic recycling: impact on the cytolytic secretory pathway

(2012) C. Capuano et al.   BLOOD

Disease Severity in Patients Infected with Leishmania mexicana Relates to IL-1β

(2012) Edith A. Fernández-Figueroa et al.   PLoS Neglected Tropical Diseases

CD8+ T-Cells Expressing Interferon Gamma or Perforin Play Antagonistic Roles in Heart Injury in Experimental Trypanosoma Cruzi-Elicited Cardiomyopathy

(2012) Jaline Coutinho Silverio et al.   PLoS Pathogens

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

(2011) Noa Novershtern et al.   CELL

Granzyme B Expression by CD8+ T Cells Is Required for the Development of Experimental Cerebral Malaria

(2011) A. Haque et al.   JOURNAL OF IMMUNOLOGY

A Role for Leukocyte-Derived IL-1RA in DC Homeostasis Revealed by Increased Susceptibility of IL-1RA-Deficient Mice to Cutaneous Leishmaniasis

(2011) Kordula Kautz-Neu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-1 signalling is dispensable for protective immunity in Leishmania-resistant mice

(2010) Kordula Kautz-Neu et al.   EXPERIMENTAL DERMATOLOGY

IL-1-induced inflammation promotes development of leishmaniasis in susceptible BALB/c mice

(2010) E. Voronov et al.   INTERNATIONAL IMMUNOLOGY

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells

(2009) Nicoletta Casartelli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Recruitment of CD8+T cells expressing granzyme A is associated with lesion progression in human cutaneous leishmaniasis

(2009) D. R. FARIA et al.   PARASITE IMMUNOLOGY