Dynamic control of plant water use using designed ABA receptor agonists

Defining and Exploiting Hypersensitivity Hotspots to Facilitate Abscisic Acid Agonist Optimization

(2019) Dezi Elzinga et al.   ACS Chemical Biology

Potent Analogues of Abscisic Acid - Identifying Cyano-Cyclopropyl Moieties as Promising Replacements for the Cyclohexenone Headgroup

(2018) Jens Frackenpohl et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Insights into the in Vitro and in Vivo SAR of Abscisic Acid - Exploring Unprecedented Variations of the Side Chain via Cross-Coupling-Mediated Syntheses

(2018) Jens Frackenpohl et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Identification and Characterization of Compounds that Affect Stomatal Movements

(2018) Shigeo Toh et al.   PLANT AND CELL PHYSIOLOGY

Small Molecule Probes Of ABA Biosynthesis And Signaling

(2018) Wim Dejonghe et al.   PLANT AND CELL PHYSIOLOGY

Where are the drought tolerant crops? An assessment of more than two decades of plant biotechnology effort in crop improvement

(2018) Michael L. Nuccio et al.   PLANT SCIENCE

The Maize ABA Receptors ZmPYL8, 9, and 12 Facilitate Plant Drought Resistance

(2018) Zhenghua He et al.   Frontiers in Plant Science

A femtomolar-range suicide germination stimulant for the parasitic plant Striga hermonthica

(2018) Daisuke Uraguchi et al.   SCIENCE

Gene duplication can impart fragility, not robustness, in the yeast protein interaction network

(2017) Guillaume Diss et al.   SCIENCE

A scaffold merging approach to Hsp90 C-terminal inhibition: synthesis and evaluation of a chimeric library

(2017) Rachel E. Davis et al.   MedChemComm

Combining chemical and genetic approaches to increase drought resistance in plants

(2017) Min-Jie Cao et al.   Nature Communications

Chemical manipulation of plant water use

(2016) Jonathan D.M. Helander et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Leveraging abscisic acid receptors for efficient water use inArabidopsis

(2016) Zhenyu Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving Winter Wheat Performance by Foliar Spray of ABA and FA Under Water Deficit Conditions

(2015) Xiaoyu Zhang et al.   JOURNAL OF PLANT GROWTH REGULATION

Dose-Response Analysis Using R

(2015) Christian Ritz et al.   PLoS One

Discovery and Characterization of Novel Selective Inhibitors of Carbonic Anhydrase IX

(2014) Virginija Dudutienė et al.   JOURNAL OF MEDICINAL CHEMISTRY

Designed abscisic acid analogs as antagonists of PYL-PP2C receptor interactions

(2014) Jun Takeuchi et al.   Nature Chemical Biology

An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants

(2013) Minjie Cao et al.   CELL RESEARCH

Terrestrial water fluxes dominated by transpiration

(2013) Scott Jasechko et al.   NATURE

ABA application to maize hybrids contrasting for drought tolerance: changes in water parameters and in antioxidant enzyme activity

(2013) Thiago Corrêa de Souza et al.   PLANT GROWTH REGULATION

Methanol fixation of plant tissue for Scanning Electron Microscopy improves preservation of tissue morphology and dimensions

(2013) Mark J Talbot et al.   Plant Methods

Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance

(2013) M. Okamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and function of abscisic acid receptors

(2012) Takuya Miyakawa et al.   TRENDS IN PLANT SCIENCE

Evolution of Abscisic Acid Synthesis and Signaling Mechanisms

(2011) Felix Hauser et al.   CURRENT BIOLOGY

Action of Natural Abscisic Acid Precursors and Catabolites on Abscisic Acid Receptor Complexes

(2011) M. Kepka et al.   PLANT PHYSIOLOGY

Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation

(2011) A. Mosquna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural and functional insights into core ABA signaling

(2010) Joshua J Weiner et al.   CURRENT OPINION IN PLANT BIOLOGY

Functional Mechanism of the Abscisic Acid Agonist Pyrabactin

(2010) Qi Hao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Towards the comprehensive, rapid, and accurate prediction of the favorable tautomeric states of drug-like molecules in aqueous solution

(2010) Jeremy R. Greenwood et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Exogenous ABA Increases Yield in Field-Grown Wheat with Moderate Water Restriction

(2010) Claudia Travaglia et al.   JOURNAL OF PLANT GROWTH REGULATION

Boolean modeling of transcriptome data reveals novel modes of heterotrimeric G-protein action

(2010) Sona Pandey et al.   Molecular Systems Biology

Structural basis for selective activation of ABA receptors

(2010) Francis C Peterson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification and mechanism of ABA receptor antagonism

(2010) Karsten Melcher et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ABA perception and signalling

(2010) Agepati S. Raghavendra et al.   TRENDS IN PLANT SCIENCE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural basis of abscisic acid signalling

(2009) Ken-ichi Miyazono et al.   NATURE

A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors

(2009) Karsten Melcher et al.   NATURE

Adding calorimetric data to decision making in lead discovery: a hot tip

(2009) John E. Ladbury et al.   NATURE REVIEWS DRUG DISCOVERY

Structural insights into the mechanism of abscisic acid signaling by PYL proteins

(2009) Ping Yin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Modulation of drought resistance by the abscisic acid receptor PYL5 through inhibition of clade A PP2Cs

(2009) Julia Santiago et al.   PLANT JOURNAL

Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins

(2009) S.-Y. Park et al.   SCIENCE

Do enthalpy and entropy distinguish first in class from best in class?

(2008) E FREIRE   DRUG DISCOVERY TODAY

Isolation of a strong Arabidopsis guard cell promoter and its potential as a research tool

(2008) Yingzhen Yang et al.   Plant Methods