Fibroblast growth factor 21induction by activating transcription factor 4 is regulated through three amino acid response elements in its promoter region

Selective Regulation of FGF19 and FGF21 Expression by Cellular and Nutritional Stress

(2015) Makoto SHIMIZU et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Fibroblast growth factor 21 participates in adaptation to endoplasmic reticulum stress and attenuates obesity-induced hepatic metabolic stress

(2014) Seong Hun Kim et al.   DIABETOLOGIA

Fibroblast Growth Factor 21 Is Regulated by the IRE1α-XBP1 Branch of the Unfolded Protein Response and Counteracts Endoplasmic Reticulum Stress-induced Hepatic Steatosis

(2014) Shan Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metformin-induced inhibition of the mitochondrial respiratory chain increases FGF21 expression via ATF4 activation

(2013) Kook Hwan Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Effects of LY2405319, an FGF21 Analog, in Obese Human Subjects with Type 2 Diabetes

(2013) Gregory Gaich et al.   Cell Metabolism

PPAR-α as a Key Nutritional and Environmental Sensor for Metabolic Adaptation

(2013) Alejandra V. Contreras et al.   Advances in Nutrition

Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation

(2012) Ana Luísa De Sousa-Coelho et al.   BIOCHEMICAL JOURNAL

FGF19(fibroblast growth factor 19) as a novel target gene for activating transcription factor 4 in response to endoplasmic reticulum stress

(2012) Makoto Shimizu et al.   BIOCHEMICAL JOURNAL

Fibroblast growth factor 21 is induced by endoplasmic reticulum stress

(2012) Frank G. Schaap et al.   BIOCHIMIE

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

(2012) Kook Hwan Kim et al.   NATURE MEDICINE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

(2008) J. Xu et al.   DIABETES