Article
Parasitology
Etienne K. Angora, Alexane Vangraefschepe, Jean-Francois Allienne, Herve Menan, Jean T. Coulibaly, Aboulaye Meite, Giovanna Raso, Mirko S. Winkler, William Yavo, Andre O. Toure, Eliezer K. N'Goran, Jakob Zinsstag, Jurg Utzinger, Oliver Balmer, Jerome Boissier
Summary: This study investigated the population genetics and genetic structure of Schistosoma haematobium in different parts of Cote d'Ivoire, as well as the frequency of S. haematobium x S. bovis hybrids in school-aged children. The results showed significant differences in genetic diversity between different sites and clustering of parasite genotypes within individual children.
Article
Public, Environmental & Occupational Health
Jean T. Coulibaly, Kigbafori D. Silue, Maxim Armstrong, Maria Diaz de Leon Derby, Michael V. D'Ambrosio, Daniel A. Fletcher, Jennifer Keiser, Karla Fisher, Jason R. Andrews, Isaac I. Bogoch
Summary: Schistosomiasis infections have a disproportionate impact on African settings. Mobile phone microscopy showed promising results for schistosomiasis control and elimination efforts, with a sensitivity of 85.7% and a specificity of 93.3% for identifying Schistosoma haematobium compared to conventional light microscopy. It also had a sensitivity of 95% for detecting egg concentrations of five or more per 10 mL of urine.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2023)
Article
Medicine, General & Internal
Beatriz Crego-Vicente, Pedro Fernandez-Soto, Begona Febrer-Sendra, Juan Garcia-Bernalt Diego, Jerome Boissier, Etienne K. Angora, Ana Oleaga, Antonio Muro
Summary: Schistosomiasis is a significant medical and veterinary concern in tropical and subtropical regions, with the emergence of natural hybrids of schistosomes posing a risk of infection to humans and animals. The hybrids have the potential to replace existing species, develop new resistances and pathologies, as well as extend host ranges. The LAMP technology shows promise in detecting pure Schistosoma species and their hybrids, offering potential for field diagnosis and disease surveillance in endemic areas where infections by schistosome hybrids are increasing.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Immunology
Mamadou Ouattara, Fidele K. Bassa, Nana R. Diakite, Jan Hattendorf, Jean T. Coulibaly, Patrick K. Yao, Yves-Nathan T. Tian-Bi, Cyrille K. Konan, Rufin K. Assare, Naferima Kone, Negnorogo Guindo-Coulibaly, Jurg Utzinger, Eliezer K. N'Goran
Summary: This study compared four different intervention strategies to interrupt the transmission of Schistosoma haematobium. The results showed that biannual mass drug administration (MDA) was the most effective in reducing infection prevalence. However, none of the strategies were able to completely interrupt the transmission of the disease within a three-year period.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Eliezer K. N'Goran, Maurice R. Odiere, Ronald Assande Aka, Mamadou Ouattara, N. A. David Aka, Bernhards Ogutu, Fredrick Rawago, Wilhelmina M. Bagchus, Matthias Boedding, Elly Kourany-Lefoll, Aliona Tappert, Xiaoyan Yin, Deon Bezuidenhout, Henk Badenhorst, Eric Huber, Benjamin Daelken, Okba Haj-Ali Saflo
Summary: This study evaluated the efficacy, safety, palatability, and pharmacokinetics of arpraziquantel tablets for treating schistosomiasis in preschool-aged children. The results showed that arpraziquantel tablets demonstrated good efficacy and safety in the treatment of schistosomiasis in preschool-aged children.
LANCET INFECTIOUS DISEASES
(2023)
Article
Infectious Diseases
Felicite Flore Djuikwo Teukeng, Manon Blin, Nicolas Bech, Marta Reguera Gomez, Rima Zein-Eddine, Alain Michel Kouam Simo, Jean-Francois Allienne, Louis Albert Tchuem-Tchuente, Jerome Boissier
Summary: This study investigated the presence of hybrids between Schistosoma haematobium and S. bovis in Cameroonian humans, as well as the genetic diversity and structure of S. haematobium populations. The results showed that hybrids accounted for 11.3% of the miracidia, and their presence correlated with increased genetic diversity in the parasite. Hybridization was found to be a major process shaping the genetic diversity of S. haematobium.
INFECTIOUS DISEASES OF POVERTY
(2022)
Article
Microbiology
Amos Mathias Onyekwere, Olivier Rey, Jean-Francois Allienne, Monday Chukwu Nwanchor, Moses Alo, Clementina Uwa, Jerome Boissier
Summary: This study provides insight into hybridization and population genetic structure of S. haematobium in Nigeria, revealing the common occurrence of hybrids in the country.
Article
Parasitology
Boris A. E. S. Savassi, Gauthier Dobigny, Jonas R. Etougbetche, Thalasse T. Avocegan, Francois T. Quinsou, Philippe Gauthier, Moudachirou Ibikounle, Helene Mone, Gabriel Mouahid
Summary: The study investigates the role of micro-mammals in the transmission of Schistosoma haematobium, S. bovis, and/or S. haematobium x S. bovis in southern Benin. Results suggest that Mastomys natalensis may serve as a new host for the transmission of S. haematobium x S. bovis, based on the presence of adult schistosomes and multi-peak cercarial chronotypes. Molecular analysis reveals the presence of both S. bovis and S. haematobium x S. bovis genotypes in the collected samples.
PARASITOLOGY RESEARCH
(2021)
Article
Microbiology
Duncan J. Berger, Elsa Leger, Geetha Sankaranarayanan, Mariama Sene, Nicolas D. Diouf, Muriel Rabone, Aidan Emery, Fiona Allan, James A. Cotton, Matthew Berriman, Joanne P. Webster
Summary: Hybridization between different species of parasites is a major concern for public and veterinary health. Recent research has shown that viable hybrids and introgressed lineages between Schistosoma spp. are common in Africa and beyond. It is unclear whether these hybrids represent recent or ancient hybridization events.
Article
Parasitology
Agniwo Privat, Boissier Jerome, Sidibe Bakary, Dembele Laurent, Diakite Assitan, Doumbo Safiatou Niare, Akplogan Ahristode, Guindo Hassim, Blin Manon, Dametto Sarah, Ibikounle Moudachirou, Spangenberg Thomas, Dabo Abdoulaye
Summary: This study analyzed the genetic profile of schistosomes in school-aged children in Mali and found a high prevalence of hybrid schistosomes.
PARASITES & VECTORS
(2023)
Article
Multidisciplinary Sciences
Eric L. Agola, Ibrahim N. Mwangi, Geoffrey M. Maina, Joseph M. Kinuthia, Martin W. Mutuku
Summary: The PCR-RFLP method targeting the ITS2 region of the ribosomal DNA was used to accurately identify mammalian schistosome cercariae shed by bulinid snails in freshwater habitats. This method can help determine transmission sites and assess the distribution of parasite species in the study area.
Article
Infectious Diseases
Nana R. Diakite, Mamadou Ouattara, Fidele K. Bassa, Jean T. Coulibaly, Yves-Nathan T. Tian-Bi, Aboulaye Meite, Jan Hattendorf, Juerg Utzinger, Eliezer K. N'Goran
Summary: In a three-year cluster randomized trial in Cote d'Ivoire evaluating different control strategies against Schistosoma haematobium, it was found that one year after the interventions, all study arms showed a significant decrease in prevalence, with arms 3 and 4 performing significantly better than arm 1. This study confirms the potential effectiveness of different intervention strategies in interrupting the seasonal transmission of S. haematobium.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2021)
Article
Parasitology
Vessaly Kallo, Zakaria Keita, Marcel Boka, Mathilde Tetchi, Komissiri Dagnogo, Max Ouattara, Djedou Martin Amalamanj, Sylvain Traore, Felix Gerber, Monique Lechenne, Jan Hattendorf, Katie Hampson
Summary: In Côte d'Ivoire, the underreporting of rabies cases and the financial burden of rabies are highlighted. A study analyzing bite records and household survey data estimated a significantly higher number of deaths and costs associated with rabies compared to official data.
Article
Microbiology
Papa Mouhamadou Gaye, Souleymane Doucoure, Bruno Senghor, Babacar Faye, Ndiaw Goumballa, Mbacke Sembene, Coralie L'Ollivier, Philippe Parola, Stephane Ranque, Doudou Sow, Cheikh Sokhna
Summary: This study describes the spatio-temporal dynamics of Bulinus senegalensis and Bulinus umbilicatus infestation by the Schistosoma haematobium group in Niakhar, Senegal. Molecular identification was performed on a total of 810 snail samples collected during the schistosomiasis transmission season in 2013. The results showed that snail infestations appear early in the rainy season, peak in the middle of the season, and decline towards the end of the season, with a higher prevalence in the northern villages compared to the southern villages.
Article
Infectious Diseases
Antoine Huguenin, Julien Kincaid-Smith, Jerome Depaquit, Jerome Boissier, Hubert Ferte
Summary: MALDI-TOF mass spectrometry was found to be effective in identifying cercariae of Schistosoma, enabling the detection of hybrids and specific species identification. This technique provides a reliable and efficient tool for the high-throughput identification of schistosomiasis cercariae in both human and non-human hosts, and has important implications for field surveys.
PLOS NEGLECTED TROPICAL DISEASES
(2023)
Article
Biochemistry & Molecular Biology
Cyril Hammoud, Stephen Mulero, Bert Van Bocxlaer, Jerome Boissier, Dirk Verschuren, Christian Albrecht, Tine Huyse
Summary: The new workflow developed in this study utilizes high-throughput amplicon sequencing to simultaneously genotype snail hosts and their infecting trematode parasites. After stringent quality control, the workflow can identify snails and trematodes with high sensitivity, successfully detecting co-infections and providing new possibilities for studying parasite-parasite interactions.
MOLECULAR ECOLOGY RESOURCES
(2022)
Article
Environmental Sciences
Delphine Destoumieux-Garzon, Franziska Matthies-Wiesler, Nicolas Bierne, Aurelie Binot, Jerome Boissier, Anais Devouge, Jeanne Garric, Kim Gruetzmacher, Christoph Grunau, Jean-Francois Guegan, Sylvie Hurtrez-Bousses, Anke Huss, Serge Morand, Clare Palmer, Denis Sarigiannis, Roel Vermeulen, Robert Barouki
Summary: The implementation of One Health/EcoHealth/Planetary Health approaches is crucial for addressing the interconnected global crises of pandemics, climate change, and biodiversity loss. Research priorities include understanding the social ecology of infectious diseases, their evolution, factors influencing susceptibility to infections, and human and ecological factors driving disease emergence. Nature-based solutions, ethical considerations, and transformative changes are essential to safeguarding the environment and human health in the face of global environmental change.
ENVIRONMENT INTERNATIONAL
(2022)
Editorial Material
Parasitology
Yohann Le Govic, Jerome Boissier, Nicolas Papon
Summary: Scientists have discovered that the beta-alanyl-tryptamine dipeptide (BATT) emitted by male schistosomes is the key factor inducing sexual maturation and egg-laying in females.
TRENDS IN PARASITOLOGY
(2022)
Article
Infectious Diseases
Felicite Flore Djuikwo Teukeng, Manon Blin, Nicolas Bech, Marta Reguera Gomez, Rima Zein-Eddine, Alain Michel Kouam Simo, Jean-Francois Allienne, Louis Albert Tchuem-Tchuente, Jerome Boissier
Summary: This study investigated the presence of hybrids between Schistosoma haematobium and S. bovis in Cameroonian humans, as well as the genetic diversity and structure of S. haematobium populations. The results showed that hybrids accounted for 11.3% of the miracidia, and their presence correlated with increased genetic diversity in the parasite. Hybridization was found to be a major process shaping the genetic diversity of S. haematobium.
INFECTIOUS DISEASES OF POVERTY
(2022)
Article
Microbiology
Amos Mathias Onyekwere, Olivier Rey, Jean-Francois Allienne, Monday Chukwu Nwanchor, Moses Alo, Clementina Uwa, Jerome Boissier
Summary: This study provides insight into hybridization and population genetic structure of S. haematobium in Nigeria, revealing the common occurrence of hybrids in the country.
Review
Environmental Sciences
Raquel Sanchez-Marques, Santiago Mas-Coma, Joaquin Salas-Coronas, Jerome Boissier, Maria Dolores Bargues
Summary: This study aims to examine the impact of the COVID-19 pandemic on schistosomiasis research, identify the most productive countries and journals, and analyze the association between total publications and socio-economic and demographic factors. The findings suggest that while there was no direct impact on schistosomiasis research, resources have been redirected to COVID-19 research, affecting the activities for the eradication of schistosomiasis.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Microbiology
Amos Mathias Onyekwere, Alejandra De Elias-Escribano, Julien Kincaid-Smith, Sarah Dametto, Jean-Francois Allienne, Anne Rognon, Maria Dolores Bargues, Jerome Boissier
Summary: This experimental study provides new insights into the mating behavior between Schistosoma bovis and S. mansoni in mixed infections in mice. The study shows that the mating between the two species is not random, with S. mansoni exhibiting greater mate recognition. The offspring generated from different mating pairs of the two species can only infect specific mollusks.
Review
Biology
Ryan Schacht, Steven R. Beissinger, Claus Wedekind, Michael D. Jennions, Benjamin Geffroy, Andras Liker, Peter M. Kappeler, Franz J. Weissing, Karen L. Kramer, Therese Hesketh, Jerome Boissier, Caroline Uggla, Mike Hollingshaus, Tamas Szekely
Summary: The adult sex ratio is found to be a fundamental determinant of behavior, involving competition, mate choice, social interactions, demographic variables, social evolution, and biodiversity conservation.
COMMUNICATIONS BIOLOGY
(2022)
Article
Dermatology
Kassi Kondo Fulgence, Kiki-Barro Pulcherie Christiane Marie, Valerie Bedia-Tanoh Akoua, Kone Estelle Gnanyo Massafoma, Angora Kpongbo Etienne, Konate-Toure Abibatou, Vanga-Bosson Abo Henriette, Miezan Assohoun Jean Sebastien, Djohan Vincent, Yavo William, Menan Eby Ignace Herve
Summary: This study investigated primary school students in rural and urban areas of southern and central Cote d'Ivoire and found significant associations between tinea capitis and factors such as age, sex, pets at home, bathing frequency, sharing of sponges, combs and towels, and hair length. In addition to tinea capitis, other superficial fungal infections were also identified among these children. Tinea capitis is common among young boys in rural areas of Cote d'Ivoire.
Article
Parasitology
Manon Blin, Bruno Senghor, Jerome Boissier, Stephen Mulero, Olivier Rey, Julien Portela
Summary: This study aimed to develop a simple molecular method using LAMP to detect environmental DNA of Bulinus truncatus, the vector of Schistosoma haematobium. The results showed that this new method can effectively detect the environmental DNA of Bulinus truncatus and even detect a fourth of positive samples that were not detectable by other methods.
PARASITES & VECTORS
(2023)
Article
Infectious Diseases
Antoine Huguenin, Julien Kincaid-Smith, Jerome Depaquit, Jerome Boissier, Hubert Ferte
Summary: MALDI-TOF mass spectrometry was found to be effective in identifying cercariae of Schistosoma, enabling the detection of hybrids and specific species identification. This technique provides a reliable and efficient tool for the high-throughput identification of schistosomiasis cercariae in both human and non-human hosts, and has important implications for field surveys.
PLOS NEGLECTED TROPICAL DISEASES
(2023)
Article
Infectious Diseases
Marta Reguera-Gomez, Maria Adela Valero, Patricio Artigas, Alejandra De Elias-Escribano, Maria Cecilia Fantozzi, Maria Pilar Luzon-Garcia, Joaquin Salas-Coronas, Jerome Boissier, Santiago Mas-Coma, Maria Dolores Bargues
Summary: This study examines the morphological variations of Schistosoma haematobium eggs from migrants in Spain, finding differences based on the geographical origin of the parasite.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Public, Environmental & Occupational Health
A. M. Onyekwere, O. Rey, M. C. Nwanchor, M. Alo, E. K. Angora, J. F. Allienne, J. Boissier
Summary: Urogenital schistosomiasis remains a public health problem in rural areas of Nigeria, especially among school-age children. Factors such as frequent contact with freshwater bodies (rivers/steams), bathing/swimming, fishing, primary education of fathers, and age are significantly associated with S. haematobium infection.
PARASITE EPIDEMIOLOGY AND CONTROL
(2022)
Article
Parasitology
Etienne K. Angora, Alexane Vangraefschepe, Jean-Francois Allienne, Herve Menan, Jean T. Coulibaly, Aboulaye Meite, Giovanna Raso, Mirko S. Winkler, William Yavo, Andre O. Toure, Eliezer K. N'Goran, Jakob Zinsstag, Jurg Utzinger, Oliver Balmer, Jerome Boissier
Summary: This study investigated the population genetics and genetic structure of Schistosoma haematobium in different parts of Cote d'Ivoire, as well as the frequency of S. haematobium x S. bovis hybrids in school-aged children. The results showed significant differences in genetic diversity between different sites and clustering of parasite genotypes within individual children.