Inhibition of cAMP/PKA Pathway Protects Optic Nerve Head Astrocytes against Oxidative Stress by Akt/Bax Phosphorylation-Mediated Mfn1/2 Oligomerization
出版年份 2019 全文链接
标题
Inhibition of cAMP/PKA Pathway Protects Optic Nerve Head Astrocytes against Oxidative Stress by Akt/Bax Phosphorylation-Mediated Mfn1/2 Oligomerization
作者
关键词
-
出版物
Oxidative Medicine and Cellular Longevity
Volume 2019, Issue -, Pages 1-16
出版商
Hindawi Limited
发表日期
2019-11-07
DOI
10.1155/2019/8060962
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mitofusin 2 Exerts a Protective Role in Ischemia Reperfusion Injury Through Increasing Autophagy
- (2018) Cheng Peng et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Structural and Functional Rescue of Chronic Metabolically Stressed Optic Nerves through Respiration
- (2018) Mohammad Harun-Or-Rashid et al. JOURNAL OF NEUROSCIENCE
- Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes
- (2018) Myoung Sup Shim et al. Cell Death & Disease
- Astrocyte remodeling without gliosis precedes optic nerve axonopathy
- (2018) Melissa L. Cooper et al. Acta Neuropathologica Communications
- Optineurin E50K triggers BDNF deficiency-mediated mitochondrial dysfunction in retinal photoreceptor cell line
- (2018) Myoung Sup Shim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Age-related accumulation of phosphorylated mitofusin 2 protein in retinal ganglion cells correlates with glaucoma progression
- (2017) Mary P. Nivison et al. EXPERIMENTAL NEUROLOGY
- Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries
- (2017) Daniel Sun et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Vitamin B 3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice
- (2017) Pete A. Williams et al. SCIENCE
- Pharmacological inhibition of S6K1 increases glucose metabolism and Akt signalling in vitro and in diet-induced obese mice
- (2016) Michael Shum et al. DIABETOLOGIA
- The glial cell modulator ibudilast attenuates neuroinflammation and enhances retinal ganglion cell viability in glaucoma through protein kinase A signaling
- (2016) Jorge L. Cueva Vargas et al. NEUROBIOLOGY OF DISEASE
- Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration
- (2016) Myoung Sup Shim et al. Scientific Reports
- An energy theory of glaucoma
- (2015) Ying Li et al. GLIA
- Mitofusin 2 ameliorates hypoxia-induced apoptosis via mitochondrial function and signaling pathways
- (2015) Cheng Peng et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Mitochondrial Morphology Differences and Mitophagy Deficit in Murine Glaucomatous Optic Nerve
- (2015) L. Coughlin et al. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
- DRP1 inhibition rescues retinal ganglion cells and their axons by preserving mitochondrial integrity in a mouse model of glaucoma
- (2015) K-Y Kim et al. Cell Death & Disease
- Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons
- (2015) L Y Shields et al. Cell Death & Disease
- Increased mitochondrial fission and volume density by blocking glutamate excitotoxicity protect glaucomatous optic nerve head astrocytes
- (2015) Won-Kyu Ju et al. GLIA
- Role of soluble adenylyl cyclase in cell death and growth
- (2014) Yury Ladilov et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The Pathophysiology and Treatment of Glaucoma
- (2014) Robert N. Weinreb et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Soluble Adenylyl Cyclase Is Necessary and Sufficient to Overcome the Block of Axonal Growth by Myelin-Associated Factors
- (2014) J. Martinez et al. JOURNAL OF NEUROSCIENCE
- Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
- (2014) Phillip M. Rappold et al. Nature Communications
- Inhibition of mitochondrial fragmentation diminishes Huntington’s disease–associated neurodegeneration
- (2013) Xing Guo et al. JOURNAL OF CLINICAL INVESTIGATION
- Inhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic function in optic nerve head astrocytes
- (2013) Y H Noh et al. Cell Death & Disease
- Oxidative stress and mitochondrial dysfunction in glaucoma
- (2012) Vicki Chrysostomou et al. CURRENT OPINION IN PHARMACOLOGY
- Soluble Adenylyl Cyclase Activity Is Necessary for Retinal Ganglion Cell Survival and Axon Growth
- (2012) R. G. Corredor et al. JOURNAL OF NEUROSCIENCE
- Structural basis of glaucoma: The fortified astrocytes of the optic nerve head are the target of raised intraocular pressure
- (2011) Chao Dai et al. GLIA
- The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic Complexes
- (2011) Suzanne Hoppins et al. MOLECULAR CELL
- Reduced cAMP, Akt Activation and p65-c-Rel Dimerization: Mechanisms Involved in the Protective Effects of mGluR3 Agonists in Cultured Astrocytes
- (2011) Daniela Durand et al. PLoS One
- Mitochondrial dynamics in cell death and neurodegeneration
- (2010) Dong-Hyung Cho et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Structural Remodeling of Fibrous Astrocytes after Axonal Injury
- (2010) D. Sun et al. JOURNAL OF NEUROSCIENCE
- Friend or Foe? Resolving the Impact of Glial Responses in Glaucoma
- (2009) Elaine C. Johnson et al. JOURNAL OF GLAUCOMA
- Oxidative injury to blood vessels and glia of the pre-laminar optic nerve head in human glaucoma
- (2008) Zac Feilchenfeld et al. EXPERIMENTAL EYE RESEARCH
- Pharmacological PKA Inhibition: All May Not Be What It Seems
- (2008) A. J. Murray Science Signaling
- The Potential Value of Natural Antioxidative Treatment in Glaucoma
- (2008) M. Mozaffarieh et al. SURVEY OF OPHTHALMOLOGY
- Susceptibility to glaucoma: differential comparison of the astrocyte transcriptome from glaucomatous African American and Caucasian American donors
- (2008) Thomas J Lukas et al. GENOME BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now