TGF-β1 accelerates the hepatitis B virus X-induced malignant transformation of hepatic progenitor cells by upregulating miR-199a-3p

JNK signaling in cancer cell survival

(2019) Qinghua Wu et al.   MEDICINAL RESEARCH REVIEWS

Autocrine transforming growth factor-β/activin A-Smad signaling induces hepatic progenitor cells undergoing partial epithelial-mesenchymal transition states

(2018) Yu Wu et al.   BIOCHIMIE

Hepatocellular carcinoma

(2018) Alejandro Forner et al.   LANCET

Liver regeneration accelerates hepatitis B virus-related tumorigenesis of hepatocellular carcinoma

(2018) Chiao-Fang Teng et al.   Molecular Oncology

EMT: Mechanisms and therapeutic implications

(2018) Mohini Singh et al.   PHARMACOLOGY & THERAPEUTICS

Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis

(2017) Daniela Sia et al.   GASTROENTEROLOGY

Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a–LCOR axis

(2017) Toni Celià-Terrassa et al.   NATURE CELL BIOLOGY

Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells

(2017) Krishna S. Tummala et al.   Cell Reports

Cancer Stem cells and their cellular origins in primary liver and biliary tract cancers

(2016) Tsunekazu Oikawa   HEPATOLOGY

TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome

(2016) Jian Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms of HBV-induced hepatocellular carcinoma

(2016) Massimo Levrero et al.   JOURNAL OF HEPATOLOGY

c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun

(2016) X Xie et al.   ONCOGENE

MicroRNA Regulates Hepatocytic Differentiation of Progenitor Cells by Targeting YAP1

(2016) Kwang Hwa Jung et al.   STEM CELLS

Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer

(2016) Kung-Kai Kuo et al.   STEM CELLS

ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation

(2015) Mir Farshid Alemdehy et al.   BLOOD

Liver Stem Cells: Experimental Findings and Implications for Human Liver Disease

(2015) George K. Michalopoulos et al.   GASTROENTEROLOGY

MiR-216b is involved in pathogenesis and progression of hepatocellular carcinoma through HBx-miR-216b-IGF2BP2 signaling pathway

(2015) F-y Liu et al.   Cell Death & Disease

CD44 is a direct target of miR-199a-3p and contributes to aggressive progression in osteosarcoma

(2015) Yan Gao et al.   Scientific Reports

JNK Signaling Mediates EPHA2-Dependent Tumor Cell Proliferation, Motility, and Cancer Stem Cell-like Properties in Non-Small Cell Lung Cancer

(2014) W. Song et al.   CANCER RESEARCH

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

Cancer stem cells in the development of liver cancer

(2013) Taro Yamashita et al.   JOURNAL OF CLINICAL INVESTIGATION

Overexpression of miR-122 promotes the hepatic differentiation and maturation of mouse ESCs through a miR-122/FoxA1/HNF4a-positive feedback loop

(2013) Xiao-Geng Deng et al.   LIVER INTERNATIONAL

Downregulation of miR-200a Induces EMT Phenotypes and CSC-like Signatures through Targeting the β-catenin Pathway in Hepatic Oval Cells

(2013) Jie Liu et al.   PLoS One

TGF-β signalling and its role in cancer progression and metastasis

(2012) Yvette Drabsch et al.   CANCER AND METASTASIS REVIEWS

Convergent Multi-miRNA Targeting of ApoE Drives LRP1/LRP8-Dependent Melanoma Metastasis and Angiogenesis

(2012) Nora Pencheva et al.   CELL

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

(2012) Wenjun Guo et al.   CELL

Hepatic transforming growth factor beta gives rise to tumor-initiating cells and promotes liver cancer development

(2012) Kun Wu et al.   HEPATOLOGY

Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma

(2012) Avijit Majumdar et al.   Nature Reviews Gastroenterology & Hepatology

Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma

(2011) Jin Hou et al.   CANCER CELL

Hepatic oval cell lines generate hepatocellular carcinoma following transfection with HBx gene and treatment with aflatoxin B1 in vivo

(2011) Chang-Hai Li et al.   CANCER LETTERS

Does the Hepatitis B Antigen HBx Promote the Appearance of Liver Cancer Stem Cells?

(2011) A. Arzumanyan et al.   CANCER RESEARCH

Hepatitis B virus X (HBx) induces tumorigenicity of hepatic progenitor cells in 3,5-diethoxycarbonyl-1,4-dihydrocollidine-treated HBx transgenic mice

(2011) Chao Wang et al.   HEPATOLOGY

miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1

(2010) Stephanie Ma et al.   Cell Stem Cell

Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-β signaling from tumor suppression to oncogenesis in early chronic hepatitis B

(2009) Miki Murata et al.   HEPATOLOGY

The etiology of liver damage imparts cytokines transforming growth factor β1 or interleukin-13 as driving forces in fibrogenesis

(2009) Hong-Lei Weng et al.   HEPATOLOGY

Significance of CD90+ Cancer Stem Cells in Human Liver Cancer

(2008) Zhen Fan Yang et al.   CANCER CELL

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY