Association of Hepatic Global DNA Methylation and Serum One‐Carbon Metabolites with Histological Severity in Patients with NAFLD

Evaluating the therapeutic potential of one-carbon donors in nonalcoholic fatty liver disease

(2019) Marwa B. Bakir et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Plasma cell-free DNA methylation: a liquid biomarker of hepatic fibrosis

(2018) Buket Yiğit et al.   GUT

Sex differences in the methylome and transcriptome of the human liver and circulating HDL-cholesterol levels

(2018) Sonia García-Calzón et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Aging and nutrition induce tissue-specific changes on global DNA methylation status in rats

(2018) Francesco Guarasci et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Epigenetics in non-alcoholic fatty liver disease

(2017) Jooho Lee et al.   MOLECULAR ASPECTS OF MEDICINE

Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease

(2016) Timothy Hardy et al.   GUT

Association of homocysteine level with biopsy-proven non-alcoholic fatty liver disease: a meta-analysis

(2016) Yining Dai et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Hepatic stellate cell transdifferentiation involves genome-wide remodeling of the DNA methylation landscape

(2016) Agata Page et al.   JOURNAL OF HEPATOLOGY

Fructose consumption induces hypomethylation of hepatic mitochondrial DNA in rats

(2016) Mirai Yamazaki et al.   LIFE SCIENCES

Associations of gut-flora-dependent metabolite trimethylamine-N-oxide, betaine and choline with non-alcoholic fatty liver disease in adults

(2016) Yu-ming Chen et al.   Scientific Reports

Global methylation, oxidative stress and relative telomere length in biliary atresia patients

(2016) Wanvisa Udomsinprasert et al.   Scientific Reports

Global DNA methylation and hydroxymethylation differ in hepatocellular carcinoma and cholangiocarcinoma and relate to survival rate

(2015) Silvia Udali et al.   HEPATOLOGY

Association of nonalcoholic fatty liver disease (NAFLD) with hepatocellular carcinoma (HCC) in the United States from 2004 to 2009

(2015) Zobair M. Younossi et al.   HEPATOLOGY

Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease

(2015) Tommy Pacana et al.   PLoS One

Serum homocysteine levels, oxidative stress and cardiovascular risk in non-alcoholic steatohepatitis

(2014) Nicoleta V. Leach et al.   European Journal of Internal Medicine

Plasma Levels of Homocysteine and Cysteine Increased in Pediatric NAFLD and Strongly Correlated with Severity of Liver Damage

(2014) Anna Pastore et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Higher serum concentrations of betaine rather than choline is associated with better profiles of DXA-derived body fat and fat distribution in Chinese adults

(2014) Y-m Chen et al.   INTERNATIONAL JOURNAL OF OBESITY

Higher Dietary Choline Intake Is Associated with Lower Risk of Nonalcoholic Fatty Liver in Normal-Weight Chinese Women

(2014) Danxia Yu et al.   JOURNAL OF NUTRITION

Methylenetetrahydrofolate Reductase Gene Polymorphism and Serum Homocysteine Levels in Nonalcoholic Fatty Liver Disease

(2013) Maria José Franco Brochado et al.   ANNALS OF NUTRITION AND METABOLISM

DNA Methylation Analysis in Nonalcoholic Fatty Liver Disease Suggests Distinct Disease-Specific and Remodeling Signatures after Bariatric Surgery

(2013) Markus Ahrens et al.   Cell Metabolism

Impact of folic acid fortification on global DNA methylation and one-carbon biomarkers in the Women's Health Initiative Observational Study cohort

(2013) Sajin Bae et al.   Epigenetics

Relationship Between Methylome and Transcriptome in Patients With Nonalcoholic Fatty Liver Disease

(2013) Susan K. Murphy et al.   GASTROENTEROLOGY

Betaine attenuates hepatic steatosis by reducing methylation of the MTTP promoter and elevating genomic methylation in mice fed a high-fat diet

(2013) Li-jun Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

NAFLD in Asia—as common and important as in the West

(2013) Geoffrey C. Farrell et al.   Nature Reviews Gastroenterology & Hepatology

Plasmatic higher levels of homocysteine in Non-alcoholic fatty liver disease (NAFLD)

(2013) Sylene Coutinho Rampche de Carvalho et al.   Nutrition Journal

Hepatic Methionine Homeostasis Is Conserved in C57BL/6N Mice on High-Fat Diet Despite Major Changes in Hepatic One-Carbon Metabolism

(2013) Christoph Dahlhoff et al.   PLoS One

Global DNA methylation levels in white blood cells as a biomarker for hepatocellular carcinoma risk: a nested case-control study

(2012) H.-C. Wu et al.   CARCINOGENESIS

Wilson's disease: Changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease

(2012) Valentina Medici et al.   HEPATOLOGY

Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine

(2011) Satish C. Kalhan et al.   CLINICAL SCIENCE

High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway

(2011) Elena Bravo et al.   Lipids in Health and Disease

Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: Impact of liver methylation of the peroxisome proliferator-activated receptor γ coactivator 1α promoter

(2010) Silvia Sookoian et al.   HEPATOLOGY

Plasma levels of asymmetric dimethylarginine in patients with biopsy-proven nonalcoholic fatty liver disease

(2010) Takhar Kasumov et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Coupling global methylation and gene expression profiles reveal key pathophysiological events in liver injury induced by a methyl-deficient diet

(2010) Volodymyr P. Tryndyak et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

(2009) Igor P. Pogribny et al.   JOURNAL OF HEPATOLOGY