The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21

A TRIM71 binding long noncoding RNA Trincr1 represses FGF/ERK signaling in embryonic stem cells

(2019) Ya-Pu Li et al.   Nature Communications

De Novo Mutation in Genes Regulating Neural Stem Cell Fate in Human Congenital Hydrocephalus

(2018) Charuta Gavankar Furey et al.   NEURON

Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition

(2018) Pooja Kumari et al.   Nature Communications

LIN41 Post-transcriptionally Silences mRNAs by Two Distinct and Position-Dependent Mechanisms

(2017) Florian Aeschimann et al.   MOLECULAR CELL

A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis

(2017) Thomas Treiber et al.   MOLECULAR CELL

Control of gene expression through the nonsense-mediated RNA decay pathway

(2017) Andrew Nickless et al.   Cell and Bioscience

Nonsense-mediated decay regulates key components of homologous recombination

(2016) Ryan Janke et al.   NUCLEIC ACIDS RESEARCH

Mechanism and regulation of the nonsense-mediated decay pathway

(2016) Nele Hug et al.   NUCLEIC ACIDS RESEARCH

SMG7 is a critical regulator of p53 stability and function in DNA damage stress response

(2016) Hongwei Luo et al.   Cell Discovery

Argonaute 2 promotes angiogenesis via the PTEN/VEGF signaling pathway in human hepatocellular carcinoma

(2015) Zhen-long Ye et al.   ACTA PHARMACOLOGICA SINICA

Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story

(2015) Feng He et al.   Annual Review of Genetics

The unfolded protein response is shaped by the NMD pathway

(2015) R. Karam et al.   EMBO REPORTS

Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes

(2015) Søren Lykke-Andersen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of elements in human long 3′ UTRs that inhibit nonsense-mediated decay

(2015) Kalodiah G. Toma et al.   RNA

Co-existence of intact stemness and priming of neural differentiation programs in mES cells lacking Trim71

(2015) Sibylle Mitschka et al.   Scientific Reports

The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation

(2015) Inga Loedige et al.   Cell Reports

Identification of a gene expression driven progression pathway in myxoid liposarcoma

(2015) Loris De Cecco et al.   Oncotarget

Linkage and Allostery in snRNP Protein/RNA Complexes

(2014) Sandra G. Williams et al.   BIOCHEMISTRY

The ubiquitin ligase human TRIM71 regulates let-7 microRNA biogenesis via modulation of Lin28B protein

(2014) Seo Hyun Lee et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation

(2014) I. Loedige et al.   GENES & DEVELOPMENT

The let-7/LIN-41 Pathway Regulates Reprogramming to Human Induced Pluripotent Stem Cells by Controlling Expression of Prodifferentiation Genes

(2013) Kathleen A. Worringer et al.   Cell Stem Cell

LIN-41/TRIM71: emancipation of a miRNA target

(2013) M. Ecsedi et al.   GENES & DEVELOPMENT

The RNA-binding protein repertoire of embryonic stem cells

(2013) S Chul Kwon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Familial aggregation of congenital hydrocephalus in a nationwide cohort

(2012) Tina Noergaard Munch et al.   BRAIN

The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling

(2012) J. Chen et al.   GENES & DEVELOPMENT

Argonaute2 promotes tumor metastasis by way of up-regulating focal adhesion kinase expression in hepatocellular carcinoma

(2012) Na Cheng et al.   HEPATOLOGY

The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing

(2012) Yu-Ling Chen et al.   JOURNAL OF PATHOLOGY

Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G

(2012) Nozhat Safaee et al.   MOLECULAR CELL

NMD: a multifaceted response to premature translational termination

(2012) Stephanie Kervestin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function

(2012) Inga Loedige et al.   NUCLEIC ACIDS RESEARCH

Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation

(2012) Hao-Ming Chang et al.   Nature Communications

The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure

(2011) Betsy R. Maller Schulman et al.   CELL CYCLE

Identification of a MicroRNA that Activates Gene Expression by Repressing Nonsense-Mediated RNA Decay

(2011) Ivone G. Bruno et al.   MOLECULAR CELL

Global Regulation on microRNA in Hepatitis B Virus-Associated Hepatocellular Carcinoma

(2011) Angela M. Liu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Autoregulation of the nonsense-mediated mRNA decay pathway in human cells

(2011) H. Yepiskoposyan et al.   RNA

On track with P-bodies

(2010) Meeta Kulkarni et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Upf1 Senses 3′UTR Length to Potentiate mRNA Decay

(2010) J. Robert Hogg et al.   CELL

The human cytoplasmic RNA terminal U-transferase ZCCHC11 targets histone mRNAs for degradation

(2010) M.-J. Schmidt et al.   RNA

TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation

(2009) Inha Heo et al.   CELL

The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2

(2009) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

The NHL-domain protein Wech is crucial for the integrin–cytoskeleton link

(2008) Birgit Löer et al.   NATURE CELL BIOLOGY

A Competition between Stimulators and Antagonists of Upf Complex Recruitment Governs Human Nonsense-Mediated mRNA Decay

(2008) Guramrit Singh et al.   PLOS BIOLOGY

Posttranscriptional Gene Regulation by Spatial Rearrangement of the 3′ Untranslated Region

(2008) Andrea B Eberle et al.   PLOS BIOLOGY