期刊
NATURE STRUCTURAL & MOLECULAR BIOLOGY
卷 26, 期 12, 页码 1085-1086出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41594-019-0333-8
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资金
- NCI NIH HHS [K99 CA241301] Funding Source: Medline
- NIGMS NIH HHS [R01 GM135671] Funding Source: Medline
Chromatin is compartmentalized spatially and temporally at multiple levels, but the precise organization of chromatin and mechanisms underlying its restructuring remain unclear. Two studies published in Cell and Nature now demonstrate the ability of chromatin to undergo liquid-liquid phase separation under physiological conditions and show that this intrinsic physicochemical property of chromatin can be regulated.
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