How evolution builds genes from scratch

Rapid evolution of protein diversity by de novo origination in Oryza

(2019) Li Zhang et al.   Nature Ecology & Evolution

Genome plasticity in Papillomaviruses and de novo emergence of E5 oncogenes

(2019) Anouk Willemsen et al.   Genome Biology and Evolution

De Novo Emergence of Peptides That Confer Antibiotic Resistance

(2019) Michael Knopp et al.   mBio

De Novo Gene Evolution of Antifreeze Glycoproteins in Codfishes Revealed by Whole Genome Sequence Data

(2017) Helle Tessand Baalsrud et al.   MOLECULAR BIOLOGY AND EVOLUTION

Random sequences are an abundant source of bioactive RNAs or peptides

(2017) Rafik Neme et al.   Nature Ecology & Evolution

NCYM, a Cis-Antisense Gene of MYCN, Encodes a De Novo Evolved Protein That Inhibits GSK3β Resulting in the Stabilization of MYCN in Human Neuroblastomas

(2014) Yusuke Suenaga et al.   PLoS Genetics

Proto-genes and de novo gene birth

(2012) Anne-Ruxandra Carvunis et al.   NATURE

De Novo Origin of Human Protein-Coding Genes

(2011) Dong-Dong Wu et al.   PLoS Genetics

A Human-Specific De Novo Protein-Coding Gene Associated with Human Brain Functions

(2010) Chuan-Yun Li et al.   PLoS Computational Biology

Origin of Primate Orphan Genes: A Comparative Genomics Approach

(2008) M. Toll-Riera et al.   MOLECULAR BIOLOGY AND EVOLUTION