Genome editing retraces the evolution of toxin resistance in the monarch butterfly

Multidrug transporters and organic anion transporting polypeptides protect insects against the toxic effects of cardenolides

(2017) Simon C. Groen et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

TraitRateProp: a web server for the detection of trait-dependent evolutionary rate shifts in sequence sites

(2017) Eli Levy Karin et al.   NUCLEIC ACIDS RESEARCH

Interacting amino acid replacements allow poison frogs to evolve epibatidine resistance

(2017) Rebecca D. Tarvin et al.   SCIENCE

Experimental test and refutation of a classic case of molecular adaptation in Drosophila melanogaster

(2017) Mohammad A. Siddiq et al.   Nature Ecology & Evolution

Gene duplications circumvent trade-offs in enzyme function: Insect adaptation to toxic host plants

(2016) Safaa Dalla et al.   EVOLUTION

Causes of molecular convergence and parallelism in protein evolution

(2016) Jay F. Storz   NATURE REVIEWS GENETICS

W-IQ-TREE: a fast online phylogenetic tool for maximum likelihood analysis

(2016) Jana Trifinopoulos et al.   NUCLEIC ACIDS RESEARCH

Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees

(2016) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

Inversions and adaptation to the plant toxin ouabain shape DNA sequence variation within and between chromosomal inversions of Drosophila subobscura.

(2016) Cinta Pegueroles et al.   Scientific Reports

Isolation, crystallization and crystal structure determination of bovine kidney Na+,K+-ATPase

(2016) Jonas Lindholt Gregersen et al.   Acta Crystallographica Section F-Structural Biology Communications

Milkweed butterfly resistance to plant toxins is linked to sequestration, not coping with a toxic diet

(2015) Georg Petschenka et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair inDrosophila

(2014) Scott J. Gratz et al.   GENETICS

The genetics of monarch butterfly migration and warning colouration

(2014) Shuai Zhan et al.   NATURE

Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila

(2014) F. Port et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STEPWISE EVOLUTION OF RESISTANCE TO TOXIC CARDENOLIDES VIA GENETIC SUBSTITUTIONS IN THE NA+/K+-ATPASE OF MILKWEED BUTTERFLIES (LEPIDOPTERA: DANAINI)

(2013) Georg Petschenka et al.   EVOLUTION

The genetic causes of convergent evolution

(2013) David L. Stern   NATURE REVIEWS GENETICS

Crystal structure of the high-affinity Na+,K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site

(2013) M. Laursen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional evidence for physiological mechanisms to circumvent neurotoxicity of cardenolides in an adapted and a non-adapted hawk-moth species

(2013) G. Petschenka et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Genomic analysis of a key innovation in an experimental Escherichia coli population

(2012) Zachary D. Blount et al.   NATURE

Insects converge on resistance

(2012) Noah K. Whiteman et al.   NATURE

Toxic cardenolides: chemical ecology and coevolution of specialized plant-herbivore interactions

(2012) Anurag A. Agrawal et al.   NEW PHYTOLOGIST

Community-wide convergent evolution in insect adaptation to toxic cardenolides by substitutions in the Na,K-ATPase

(2012) S. Dobler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parallel Molecular Evolution in an Herbivore Community

(2012) Y. Zhen et al.   SCIENCE

Evaluation of potential reference genes for reverse transcription-qPCR studies of physiological responses in Drosophila melanogaster

(2011) Fleur Ponton et al.   JOURNAL OF INSECT PHYSIOLOGY

Evolutionary paths to antibiotic resistance under dynamically sustained drug selection

(2011) Erdal Toprak et al.   NATURE GENETICS

Molecular spandrels: tests of adaptation at the genetic level

(2011) Rowan D. H. Barrett et al.   NATURE REVIEWS GENETICS

Target-site sensitivity in a specialized herbivore towards major toxic compounds of its host plant: the Na+K+-ATPase of the oleander hawk moth (Daphnis nerii) is highly susceptible to cardenolides

(2009) Georg Petschenka et al.   CHEMOECOLOGY

Novel mutations affecting the Na, K ATPase alpha model complex neurological diseases and implicate the sodium pump in increased longevity

(2009) Lesley J. Ashmore et al.   HUMAN GENETICS

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY