Oral administration of hydroxylated-graphene quantum dots induces intestinal injury accompanying the loss of intestinal stem cells and proliferative progenitor cells

Nitrogen-doped graphene quantum dots (N-GQDs) perturb redox-sensitive system via the selective inhibition of antioxidant enzyme activities in zebrafish

(2019) Shun Deng et al.   BIOMATERIALS

Hydroxylated-Graphene Quantum Dots Induce DNA Damage and Disrupt Microtubule Structure in Human Esophageal Epithelial Cells

(2018) Ming Li et al.   TOXICOLOGICAL SCIENCES

Acute Oral Administration of Single-Walled Carbon Nanotubes Increases Intestinal Permeability and Inflammatory Responses: Association with the Changes in Gut Microbiota in Mice

(2018) Hanqing Chen et al.   Advanced Healthcare Materials

Oral Nanoparticles Exhibit Specific High-Efficiency Intestinal Uptake and Lymphatic Transport

(2018) Kyoung Sub Kim et al.   ACS Nano

Cytotoxicity and autophagy induction by graphene quantum dots with different functional groups

(2018) Yichun Xie et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Biocompatibility and toxicity of graphene quantum dots for potential application in photodynamic therapy

(2018) Tanveer A Tabish et al.   Nanomedicine

Toxicity of Organic Fluorophores Used in Molecular Imaging: Literature Review

(2018) Raphael Alford et al.   Molecular Imaging

Intestinal organoids: A new paradigm for engineering intestinal epithelium in vitro

(2018) Sara Rahmani et al.   BIOMATERIALS

Graphene quantum dots for cancer targeted drug delivery

(2017) Daniela Iannazzo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Interplay between metabolic identities in the intestinal crypt supports stem cell function

(2017) Maria J. Rodríguez-Colman et al.   NATURE

Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca2+ signaling in the Drosophila midgut

(2017) Chiwei Xu et al.   eLife

Hydroxylated-graphene quantum dots induce cells senescence in both p53-dependent and -independent manner

(2016) Xin Tian et al.   Toxicology Research

Intrinsic peroxidase-like catalytic activity of nitrogen-doped graphene quantum dots and their application in the colorimetric detection of H2O2 and glucose

(2015) Liping Lin et al.   ANALYTICA CHIMICA ACTA

Can graphene quantum dots cause DNA damage in cells?

(2015) Dan Wang et al.   Nanoscale

Graphene quantum dots induce apoptosis, autophagy, and inflammatory response via p38 mitogen-activated protein kinase and nuclear factor-κB mediated signaling pathways in activated THP-1 macrophages

(2015) Yiru Qin et al.   TOXICOLOGY

The in vitro and in vivo toxicity of graphene quantum dots

(2014) Yu Chong et al.   BIOMATERIALS

Stem cells and the impact of ROS signaling

(2014) C. L. Bigarella et al.   DEVELOPMENT

Mechanisms of nanotoxicity: Generation of reactive oxygen species

(2014) Peter P. Fu et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Hydroxylation of multi-walled carbon nanotubes reduces their cytotoxicity by limiting the activation of mitochondrial mediated apoptotic pathway

(2014) Zhenbao Liu et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

A universal fluorescence sensing strategy based on biocompatible graphene quantum dots and graphene oxide for the detection of DNA

(2014) Z. S. Qian et al.   Nanoscale

Effects of subchronic exposure of silver nanoparticles on intestinal microbiota and gut-associated immune responses in the ileum of Sprague-Dawley rats

(2014) Katherine Williams et al.   Nanotoxicology

Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy

(2014) T Grabinger et al.   Cell Death & Disease

A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation

(2014) Jiechao Ge et al.   Nature Communications

Cellular distribution and cytotoxicity of graphene quantum dots with different functional groups

(2014) Xiaochan Yuan et al.   Nanoscale Research Letters

Graphene Quantum-Dot-Doped Polypyrrole Counter Electrode for High-Performance Dye-Sensitized Solar Cells

(2013) Lijia Chen et al.   ACS Applied Materials & Interfaces

In Vivo Biodistribution and Toxicology of Carboxylated Graphene Quantum Dots

(2013) Md Nurunnabi et al.   ACS Nano

Paneth Cells: Maestros of the Small Intestinal Crypts

(2013) Hans C. Clevers et al.   Annual Review of Physiology

Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration

(2013) Ciara Metcalfe et al.   Cell Stem Cell

γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies

(2013) Vanessa Valdiglesias et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Focusing on luminescent graphene quantum dots: current status and future perspectives

(2013) Lingling Li et al.   Nanoscale

Intestinal label-retaining cells are secretory precursors expressing Lgr5

(2013) Simon J. A. Buczacki et al.   NATURE

Broad-Spectrum Antibacterial Activity of Carbon Nanotubes to Human Gut Bacteria

(2013) Hanqing Chen et al.   Small

Enhancing Cell Nucleus Accumulation and DNA Cleavage Activity of Anti-Cancer Drug via Graphene Quantum Dots

(2013) Chong Wang et al.   Scientific Reports

Insight into the Cellular Internalization and Cytotoxicity of Graphene Quantum Dots

(2013) Congyu Wu et al.   Advanced Healthcare Materials

The p53 network: cellular and systemic DNA damage responses in aging and cancer

(2012) H. Christian Reinhardt et al.   TRENDS IN GENETICS

Redox Regulation by Keap1 and Nrf2 Controls Intestinal Stem Cell Proliferation in Drosophila

(2011) Christine E. Hochmuth et al.   Cell Stem Cell

Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair

(2011) Lisa Woodbine et al.   NUCLEIC ACIDS RESEARCH

Models for oral uptake of nanoparticles in consumer products

(2011) Eleonore Fröhlich et al.   TOXICOLOGY

An Electrochemical Avenue to Green-Luminescent Graphene Quantum Dots as Potential Electron-Acceptors for Photovoltaics

(2010) Yan Li et al.   ADVANCED MATERIALS

Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs

(2009) Wolfgang G. Kreyling et al.   INHALATION TOXICOLOGY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE