IL-4Rα expression by airway epithelium and smooth muscle accounts for nearly all airway hyperresponsiveness in murine allergic airway disease

Psoriasis induced by dupilumab therapy

(2019) G. Safa et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma

(2018) Klaus F. Rabe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma

(2018) Mario Castro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dupilumab-Induced Follicular Conjunctivitis

(2018) Elizabeth Shen et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

The vascular endothelial specific IL-4 receptor alpha–ABL1 kinase signaling axis regulates the severity of IgE-mediated anaphylactic reactions

(2017) Amnah Yamani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NKT cells contribute to basal IL-4 production but are not required to induce experimental asthma

(2017) Christopher G. McKnight et al.   PLoS One

CXCR3 Requirement for the Interleukin-13–Mediated Up-Regulation of Interleukin-13Rα2 in Pulmonary Fibroblasts

(2015) Jennifer C. Barnes et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mechanisms of airway hyper-responsiveness in asthma: the past, present and yet to come

(2015) D. G. Chapman et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Mast cell production and response to IL-4 and IL-13

(2015) Jamie J.A. McLeod et al.   CYTOKINE

Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice

(2015) Inuk Zandvakili et al.   PLoS One

IL-4R  Expression by Bone Marrow-Derived Cells Is Necessary and Sufficient for Host Protection against Acute Schistosomiasis

(2014) D. R. Herbert et al.   JOURNAL OF IMMUNOLOGY

IL-4 blocks TH1-polarizing/inflammatory cytokine gene expression during monocyte-derived dendritic cell differentiation through histone hypoacetylation

(2013) María López-Bravo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dupilumab in Persistent Asthma with Elevated Eosinophil Levels

(2013) Sally Wenzel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice

(2011) Charles Perkins et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Evolution of Th2 Immunity: A Rapid Repair Response to Tissue Destructive Pathogens

(2011) Judith E. Allen et al.   PLoS Pathogens

Expression of IL-4 receptor α on smooth muscle cells is not necessary for development of experimental allergic asthma

(2010) Frank Kirstein et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Usefulness and optimization of mouse models of allergic airway disease

(2008) Fred D. Finkelman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Efficient colonic mucosal wound repair requires Trem2 signaling

(2008) H. Seno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA